[Local radiation damage: the characteristics of its pathogenesis, diagnosis and treatment].
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Biomedical subjects
Publications and source records attributed to M S Bardychev.
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Two patients who received combined chemo- and radiotherapy for Hodgkin's disease developed secondary tumors in irradiated fields by 15 and 24 years, respectively. All the necessary criteria for the diagnosis of radiation-induced sarcoma have been found.
The article deals with the results of ultrasonic examination (USE) of 39 patients with secondary edema of the lower extremities. The authors developed a USE method which yields objective data characterizing changes of the structure, thickness, boundaries, and firmness of the soft tissues in lymphedema of the lower extremities of various severity. It was established that lymphostasis produced a characteristic ultrasonic pattern, which, as claimed by the author, may be used in differential diagnosis of lymphatic and venous edema of the extremities.
The paper presents the results of diagnosis and treatment of 155 patients with intrapelvic radiation fibrosis (IRF). IRF mainly manifests itself as a disorder of the urinary function. The use of presacral disorders in complex treatment increases the efficacy of therapeutic measures.
In 6 patients with sarcomas of the bones of the crus at different periods following radiotherapy the authors have revealed pathologic reconstruction of the structure of the tibia. A roentgenologic picture of the changes in the course of the dynamic observation of the patients and their treatment is presented. It has been demonstrated that the conservative treatment effective.
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Acupuncture was carried out in 141 sufferers from late-onset radiation injuries to skin and soft tissues. 122 patients (86%) revealed clinical manifestations of edema of varying gravity in arms and legs, while 19 (14%) suffered radiation-induced neuritis or plexitis unaccompanied by edema. Radionuclide and rheographic studies as well as evaluation of hemostatic function showed acupuncture to be an effective treatment for edema and pain. It also improved lymph flow, rheovasographic indexes and normalized hemostasis. The best results were obtained in cases of stage I-II edema.
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The author has summed up the results of therapy and a clinical course of radiation injuries developing mostly after radiotherapy of different tumors in 3870 patients.
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An experience with examination and treatment of 314 cases of late-onset intestinal lesions which developed following radiotherapy of abdominal and pelvic cavity tumors are discussed.
The paper is concerned with the results of examination and treatment of 140 patients with late radiation injuries of the lungs developing in a late period after combined treatment (operation + radiotherapy) of breast cancer. The sooner the treatment was initiated, the more effective it was.
The authors presented the results of laser stimulation of reparation processes in 25 patients with late radiation skin ulcers. Short-term therapeutic results turned out to be favorable in 18 (72%) patients, a complete cicatrization of ulcers was observed in 9 patients, significant improvement in 9.