[Moments in the history of Romanian epidemiology].
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Biomedical subjects
Publications and source records attributed to M Sabău.
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The higher incidence of HB8Ag/ayw (71%) in sera collected from acute viral hepatitis cases, as well as from patients with chronic active hepatitis, healthy carriers and blood donors of 20 Romanian counties emphasizes the local prevalence of the ayw determinant in our country.
250 HBsAg-positive sera from apparently healthy blood donors were tested for HBeAg and anti-HBe by immunodiffusion(ID) and counterelectrophoresis(CEP). HBeAg was identified in 2.4% and anti-HBe in 34% of the sera. After serum concentration a larger rate of both HBeAg and anti-HBe could be detected by ID. There was no difference in sensitivity between ID and CEP techniques in the detection of the e-system. There was no correlation between HBeAg or anti-HBe and HBsAg subtypes. Generally sera containing HBeAg showed higher titers of HBsAg in complement fixation.