PubMed Health⌕ Search

Biomedical subjects

M Shinoda

Publications and source records attributed to M Shinoda.

At least 271 records · Page 15Linked to original sources
PubMed1979

Purification of leukocytosis-promoting substance from bovine parotid gland extract.

A leukocytosis-promoting substance was purified from a crude bovine parotid gland extract. The purified substance was proved to be a single component by polyacrylamide gel disc electrophoresis. It stimulates an increase of peripheral leukocyte numbers in rabbits. The molecular weight of the physiologically active component was estimated to be 4.5 . 10(4), and the component was found by sodium dodecyl sulfate polyacrylamide gel electrophoresis to be dissociated into two subcomponents.

Animals↗
PubMed1979

An experimental study of the preparation of a substitute stomach following total gastrectomy in the rat.

In 38 rats, a substitute stomach was prepared through transplantation of the ileocaecal intestinal portion following total gastrectomy. 47% of rats tolerated the operation. The survival rate of the tolerated rats for 360 days after the surgery was 16%. Their body weight corresponded to 77% of that in the untreated control rats on the 360th day after the operation. Compared to other conventional methods of total gastrectomy and reconstruction, this method is quite outstanding. From this experimental fact, the preparation of a substitute stomach through transplantation of the ileocaecal intestinal segment seems possible to supplement a part of the defects in the agastric syndrome accompanying total gastrectomy for a prolonged period.

Animals↗
PubMed1979

Convulsions from excessive dosage of nalidixic acid: a case report.

A 4-year-old girl who developed convulsions after an accidental ingestion of excessive dosage (50 mg/kg) of nalidixic acid, while treated with the drug (50 mg/kg/day) over 30 days for a urinary tract infection, was reported. Thirty minutes after ingestion, vomiting, tonic-clonic seizures, and abnormal movements were supervened. After ninety minutes, the serum levels of nalidixic acid and hydroxynalidixic acid were 146.1 and 48.9 microgram/ml, respectively. In controls, the mean levels of nalidixic acid and hydroxynalidixic acid were 7.8 +/- 6.8 (SD) and 3.02 +/- 2.6 microgram/ml, respectively.

Child, Preschool↗
PubMed1978

An analysis of the fatty acid composition of total lipids from mycoplasmas.

The fatty acid composition of the total lipids obtained from 9 species (22 strains) of Mycoplasma and 3 species (7 strains) of Acholeplasma was determined by gas-liquid chromatography (GLC). The major fatty acids of the Mycoplasma species were palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1), and linoleic acid (C18:2). Lauric acid (C12:0) and myristic acid (C14:0) were present in small amounts in this genus. For the Mycoplasma species, the most prevalent fatty acid was C16:0 or C14:0, and other leading fatty acids were C12:0, C18:0, C18:1 and C18:2. A substantial amount of C12:0 and C14:0 was found in the Acholeplasma species. It was confirmed that C12:0 and C14:0 were synthesized de novo, based on the fact that 14C-acetate was incorporated into these acids. The total percentage of C16 fatty acid was less than that of C18 fatty acids in all the strains of Mycoplasma and Acholeplasma except 4 strains. This may be related to osmo-regulation of the L-forms of Streptococci as mentioned in other reports.

Acholeplasma↗