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Biomedical subjects

M Spaczyński

Publications and source records attributed to M Spaczyński.

At least 37 records · Page 2Linked to original sources

[The clinical value of DNA ploidy in ovarian cancer].

The aim of this study was to correlate the DNA ploidy with clinical parametres in ovarian cancer. For assessment of DNA cellular abnormalities it was used a new method-flow cytometry. Diploidy was stated in 24 cases (55.8%) and aneuploidy in 19 cases (44.2%). In comparing to FIGO staging the frequency of aneuploidy increased from I to IV stage and it was statistic significant. In comparing to vaginal ultrasound examination the difference was not so significant, but the most often aneuploidy was observed in solid tumors. The results of this study show the usefulness of flow cytometry in diagnosis of ovarian cancer.

Adult↗

[The evaluation of ovarian tumor vascularization using color Doppler transvaginal ultrasonography].

The aim of this study was the evaluation of blood flow factors prognostical value in differentiation of malignancy among ovarian tumors--sensitivity of this method was 81.8--90.9%, specificity was 88.5%, positive predict value 75.0--76.9% and negative predict value 92.0--95.8%. It was stated that Dopplers method is very usefull in diagnosis of malignant ovarian neoplasms. Moreover it was shown that pulsation index (PI) is more suitable than resistance index (RI), particularly in preoperative diagnostics.

Female↗

[Evaluation of blood flow in uterine arteries in patients with cancer of the cervix uteri using transvaginal color doppler ultrasonography].

The purpose of the study was to estimate blood flow in uterine arteries in patients with uterus cervix invasive carcinoma. In the study the colour Doppler ultrasonography was used. It was found out that in the group of patients with uterus cervix carcinoma pulsation index (PI)--1.82 +/- 1.44 as well as resistance index (RI)--0.72 +/- 0.12 are statistically significantly lower than adequate indices in the control group (PI)--3.36 +/- 1.04 and (RI)--0.81 +/- 0.17 (p < 0.05).

Adult↗

[Uterine papillary serous carcinoma].

Two cases of uterine papillary serous carcinoma are presented. Attention to propensity for deep myometrial invasion, upper abdominal spread and high relapse rate are paid. Patients require combined treatment.

Aged↗

[Evaluation of qualitative values of blood flow indices in uterine and arcuate arteries during the third trimester of normal pregnancy].

We presented in our study obtained values of qualitative indices of blood flow in uteroplacental circulation in the third trimester of normal pregnancy. We performed examinations in 154 pregnant women with pregnancy age of 32-42 wk. We evaluated blood flow velocity in uterine and arcuate arteries by means of qualitative analysis of blood flow waveforms. We proved that in the third trimester of normal pregnancy qualitative parameters of blood flow decrease slightly what may suggest that there is systematic placental perfusion increase.

Adolescent↗

[Evaluation of the influence of placental localization on qualitative estimation of waveforms of blood flow velocity in uterine and arcuate arteries in third trimester physiologic pregnancy].

We presented in our study methods and results of blood flow measurements with Doppler ultrasound in uterine and arcuate arteries in relation to localization of placenta in physiological pregnancy. We performed examinations in 154 pregnant women with pregnancy age of 32-42 wk. On the basis of qualitative analysis of blood flow waveforms we discovered the difference in the blood flow in utero-placental compartment in relation to placental localization and we proved that this change takes place in uterine as well an in arcuate arteries.

Adult↗

[Doppler evaluation of blood flow in the umbilical artery when confronted with morphologic changes in human placenta of pregnancy complicated by diabetes].

Doppler ultrasound velocimetry in umbilical artery was performed in 23 pregnant women in different classes of the diabetes. Results obtained were compared with the afterbirths' morphology. Strict correlation was found between arteries obliteration in the placenta and vascular resistance in higher classes of the diabetes. Normal structure of the villi with signs of their morphological maturity has basic influence on proper umbilical artery flow maintenance.

Adult↗

[Evaluation of the clinical value in doing complex analysis of blood flow velocity parameters of the umbilical artery for determining prognosis of fetal status].

Complex analysis of the clinical value of the doppler flow indices was undertaken. A/B, RI and PI were compared separately and in different combinations with fetal status and neonate's condition. Statistical analysis revealed that complex and detailed analysis of few quality indices is of greater clinical value and increases sensitivity, specificity and positive predictive value of the doppler technique in the sense of prognosis of fetal distress and neonate's condition.

Adult↗

[Usefulness of transvaginal ultrasound and hysteroscopy in diagnosing endometrial hyperplasia and endometrial carcinoma].

Modern methods enabling evaluation of endometrium in all phases of the menstrual cycle were presented. Transvaginal ultrasound does not give characteristic pictures. The most frequently observed sonographic features in endometrial hyperplasia and endometrial carcinoma were compared. Most frequently, in 29% we observed the thickening of the endometrium. The enlargement of the uterine body was detected in 27%. The dominant feature in endometrial carcinoma was distortion or lack of medium-focus echo-90%. Different echogenicity was observed in 69% of all cases. Application of hysteroscopy enables us to visualize changed endometrium and also to sample focal lesions for histopathological examination. Endometrial carcinoma was detected in all analyzed cases with application of hysteroscopy and ultrasound. Pathological endometrial hyperplasia was diagnosed by ultrasound only in 44% and with application of hysteroscopy in 84% of all material.

Adult↗

[Uterine endoscopy. I. Role of hysteroscopy in gynecologic oncology].

The historical sketch of development of hysteroscopy is presented. At the present time instrumentation consists of the set of precision lenses system, with "cold light" source and the light conveying glass fibre. In order to obtain good visibility and ability to perform surgeries one uses various media for distention of the uterine walls. For diagnostic hysteroscopy the most commonly used medium is carbon dioxide. The most advantageous substances when performing intrauterine procedures are liquid media such as: HYSKON, MANNITOL and GLUCOSE SOLUTION. Indications for hysteroscopy are numerous and they divide into diagnostic and surgical. Hysteroscopy is a very useful procedure in diagnosis and therapy of sterility and diagnosis and therapy of hyperplastic changes of the endometrium. Introduction of resection of the endometrium to hysteroscopy allows us, in certain situations to limit the number of laparatomies. Complications after hysteroscopy do not differ from complications following other gynecological surgeries.

Endometrial Hyperplasia↗

[Diagnostic and therapeutic procedures in preinvasive disease of the cervix and cervical cancer in pregnancy].

154 pregnant women with dysplasia and cervical carcinoma of the uterus treated in the Institute in years 1953-1990 underwent investigation. We notice that only 50 pathologies were diagnosed in I trimester of pregnancy and 85% constituted precancerous and early forms of carcinoma of the uterine cervix. Authors presented the model of management and care of pregnancy, labour and puerperium in these patients. Due to this procedure we obtained 90% compatibility of preliminary and final diagnosis.

Female↗

[Ultrasonic diagnosis in gynecologic oncology].

The author presents possibilities provided by ultrasonographic examinations in the diagnostics of neoplasms in female genital organs. Characteristic pictures of genital organs and neoplasms in uterus and ovaries have been described. The author emphasises the usefulness of the method in differentiating the character, source of a neoplasm and its extent.

Diagnosis, Differential↗