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Biomedical subjects

M Steinhardt

Publications and source records attributed to M Steinhardt.

At least 73 records · Page 4Linked to original sources

[The reference values of the hemoglobin content, the hematocrit and the mean concentration of corpuscular hemoglobin of calves reared without iron substitution. 1. Dependence on the rearing period].

A total of 1.088 blood samples (1 to 6 per animal) were taken from 491 rearing calves in the colostral period, the milk feeding period and the weaning period (at the age of 4, 22, 51, 79, 105, 122 and 145 days); the hemoglobin content (Hb), the hematocrit (Hc) resp. the mean corpuscular hemoglobin concentration (MCHC) were determined resp. calculated. Hb, Hc and MCHC were drawn in diagrams in dependence on the rearing period as arithmetic means with standard deviations, as quartiles and as frequency distributions on an interval scale. During the rearing periods with milk feeding the anaemic frequency was considerable. Anaemia resp. hypochromia frequency had an inverse relation to the developing increase of concentrated feed and roughage consumption and thus makes it probable that the cause of anaemia is the intake and/or absorption of iron insufficient for the weight gain performance achieved. The consumption of solid feed by the hematologically examined calves developed more quickly than in other GDR rearing farms due to the early ad libitum supply with this feed component and the composition of fluid feed with milk. Reference is made that the frequency of hypoferric anaemia can also be considerable during the milk feeding period in the intensive rearing of lambs and kids if an effective iron intervention is not made.

Anemia↗

[Normal values for the hemoglobin content, hematocrit and the average corpuscular hemoglobin concentration in calves for rearing: fall study, 1976].

Raised calves were analysed for their frequency distributions of haemoglobin, haematocrit, and mean corpuscular haemoglobin concentration, depending on phases of keeping, in two cross-section (n = 146 and 196) and one longitudinal section studies (the latter on three dates, n = 149, 144, and 141). Race, birth weight, age, and live weight of the calves and their fathers as well as lactation age of their mothers were used for reference. All animal groups exhibited at any time of testing significant deviations from Gauss' distribution in all tests undertaken to verify the normality of frequency distributions of the above haematological variables. Those frequency distributions exhibited clearly visible variations, depending on phases of keeping. A concept to meet such conditions is proposed for evaluation of all variables of the red blood count.

Aging↗

[Hematological studies of boars during testing for breeding suitability].

Studies were conducted into haemoglobin and haematocrit levels as well as into mean corpuscular haemoglobin concentrations (MCHC) of venous blood samples which had been collected from 600 boars, aged between 180 and 200 days and weighing between 90 kg and 100 kg. The following values, per 100 millilitres of erythrocytes, were obtained: 13.36 +/- 1.06 g of haemoglobin, 42.16 +/- 3.3 per cent of haematocrit, and 31.74 +/- l.6 g of MCHC. Seven random samples were investigated, and the following values were beyond normal limits: 34.91 per cent of haemoglobin (22.22-44.91 per cent), 23.96 per cent of haematocrit (12.28-46.16 per cent), and 61.89 per cent of MCHC (35.08-78.94 per cent). The above results were compared with those which had been obtained from the same animals, when aged between 105 and 110 days and weighing between 40 kg and 45 kg. Due consideration was given also to the origin of the animals which had come from four different farms as well as to the extent to which deficit situations had developed and to disorders in haematopoiesis.

Age Factors↗

[Investigations of anemia of male rearing calves. 1. Reference conditions and anemia frequency].

In a longitudinal investigation (3 points of time n = 214, 206 resp. 202) the hemoglobin quota (Hb), the hematocrit (Hct) resp. the average corpuscular hemoglobin concentration (MCHC) were analysed at male calves receiving semi-liquid feed in the transitional period from pre-ruminal to ruminal digestion (56d). Breed, live weight development, consumption of milk, concentrated feed resp. dried forage, diseases of the calves as well as the father and the milk yield resp. the lactation age of the mother were registered as reference conditions. The percentage of calves with an Hb less than 10.5 g/dl was at the three points of time 50.00%, 86.41% resp. 41.58%, of calves with an Hct less than 33,5% it was 43.46%, 66.02% resp. 31.68% and of calves with an MCHC less than 30.5 g Hg/dl erythrocytes 51.87%, 76,21 resp. 47,03%. 21.50%, 33.50% resp. 4.46% of all test animals even had an Hb of less than 8.5 g/dl.

Anemia↗

[Anemia of male rearing calves. 2. Duration of anemia].

From 203 male rearing calves in a longitudinal study during the first rearing period in a rearing farm the time could be determined in which the hemoglobin quota, the hematocrit resp. the average corpuscular hemoglobin concentration were lower than 10,5 g/dl, 33% resp. 30.5 g Hb/dl erythrocytes. The average duration of anaemia was 45, 29.5 resp. 44 days of the total of 56 keeping days in this rearing range (80.4%, 52.7% resp. 78.6% of the keeping period). During this rearing period 89.2%, 71.4% resp. 90.6% of all animals were anaemic for a shorter or longer time. With 29.8%, 26.2% resp. 29.9% of the anaemic calves the anaemic phase exceeded 56 days.

Anemia↗

[Anemia of male rearing calves. Connections between anemia and feed consumption, development of the live weight and disease development].

Calves in a longitudinal investigation over the first rearing period in a rearing farm were grouped according to their anaemic status under consideration of the degree of severity and the duration on the basis of the hemoglobin contents resp. the hematocrit values on the 3rd, 28th and 56th rearing day. There were significant differences between the groups of calves with differing anaemia status concerning the absolute and relative feed consumption (milk, concentrated feed, hay resp. iron), the development of the live weight as well as the frequency of the treatment against pneumonia and/or diarrhoea.

Anemia↗

[Blood acid-base status in fattening pigs in exhausting physical stress of high intensity].

Reported in this paper are changes in the acid-base state and lactic concentration of blood and muscle samples taken from 28 pigs prior to, during, and after high-intensity exhausting stress applied at ambient temperatures between 17 degrees C and 21 degrees C and at 35 degrees C. Close correlations were found to exist between acid-base states, on the one hand, and lactic acid concentrations, on the other. The lactic acid concentrations reached in blood plasma were between 30 and 40 mHol/1, pH being below 7.0 and BE values being smaller than -22 mHol/1. Close relationships were established between the lactic acid concentration of venous blood plasma, blood pH, and the pH of the musculus longissimus dorsi. Respiratory compensation was of minor importance with ambient temperatures between 17 degrees C and 21 degrees C, but it was of considerable effectiveness at 35 degrees C.

Acid-Base Equilibrium↗

Massive lower gastrointestinal bleeding: an unusual complication of Crohn's disease.

Massive rectal bleeding may complicate Crohn's disease at any stage and tends to be persistent. Limited experience gained with this complication supports the use of selective agiography followed by conservative resection as the management of choice. Results of experimental studies suggest that selective infusion of vasopressors may be safely attempted when hemorrhage complicates Crohn's disease in its early stages but is probably too hazardous in cases in which the disease is more advanced.

Adult↗

[Meat quality in swine. 5. Relationships between blood parameters and meat quality].

The responses of haemoglobin, haematocrit, glucose, and lactate to natural strain and their relationships to pork quality were studied in several experiments with 155 animals. Stress associated with blood-taking following snout-loop fixation, evacuation, transport, and stunning led to excessive excitation which, in turn, caused deflection of the above parameters. Their correlations with criteria of pork quality are unimportant. Assessment of individual strainability of the neuromuscular system on the basis of the above stresses and blood parameters, therefore, does not seem to be promising at all. This result has been confirmed by repeated testing of the above criteria between evacuation and bleeding. The animals tested responded quite variably. Their pork qualities were both "normal" and "impaired".

Acidosis↗

[Reactions of the domestic pig to exhausting motor stress of middle intensity].

The VO 2max value was established from twelve pigs, followed by checks of their responses to endurance stress (walk 0.7 m/sec, ambient temperatures between 22 degress C and 24 degrees C, relative humidities between 67 and 78 per cent). Also measured were the rectal temperature, heart rate, respiratory rate, haemoglobin level of the blood, haematocrit, mean corpuscular haemoglobin concentration, plasma volume, blood volume, total haemoglobin, plasma glucose concentration and plasma lactid acid concentration. A differentiation could be made between one group weighing between 53.3 +/- 2.47 kg and enduring 97 +/- 9 minutes and another weighing 60.0 +/- 1.38 kg and enduring 36 +/- 6 minutes. The two groups differed from one another for their plasma and blood volumes, their values being 42.6 +/- 3.8 ml/kg and 67.5 +/- 7.5 ml/kg or 33.5 +/- 3.4 ml/kg and 52.2 +/- 5.9 ml/kg. The groups produced quantitatively different responses to endurance stress. The demands implied in endurance were widely met by the circulatory system, while the energy transfer was characterised primarily by aerobic energy collection.

Animals↗

[Acid-base status in the blood of domestic pigs during exhausting locomotor stress of small and medium intensity].

Twenty-two fattening pigs were stressed until their rectal temperatures had reached 42 degrees C. The means of stress included walking on moving conveyor belt at ambient temperatures between 22 degrees C and 27 degrees C and relative humidities between 69 and 98%, belt speeds of 0.7 m/s, 1.3 m/s or 0.7 m/s, and stimulation by means of a forcing rod. Rectal temperature, respiratory frequency, lactic acid level in blood plasma, pH, as well as pCO2 and base excess in the blood were measured prior to, during, and after stressing. Gasping was strongly pronounced due to severe alkalisis, but it was somewhat mitigated on running on the belt with exposure to additional stress on account of lactic acid accumulation in the plasma.

Acid-Base Equilibrium↗

[Muscle meat quality in swine. 4: Response of fattening pigs to removal from pigsty and transport to slaughterhouse].

Blood was sampled through indwelling catheters from pigs taken to places for slaughter by various means of transport. Sampling took place at different measuring points between removal from pig pens and actual slaughter. The blood was tested for haemoglobin, haematocrit, glucose, and lactate. The following results were obtained: Removal and transport led to strong Hb and medium Hk rises. The levels, however, returned to normal after one-and-a-half to two hours rest. Stresses caused prior to and during anaestheria led to considerable rise of Hk and Hb as well as to maximum lactate deflection. The latter excitations superimposed all the preceding reactions of the organism. The increased of Hb, Hk, and lactate recorded from animals slaughtered as little as 20 minutes after arrival were higher than those established from animals that had been allowed some rest in between. Transport losses were reduced when the animals were moved in containers due to less motoric stress. However, no mitigation of pork quality setback can be expected as long as strong excitation continues to be caused in the animals before slaughter.

Abattoirs↗