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Biomedical subjects

M Steinhardt

Publications and source records attributed to M Steinhardt.

At least 91 records · Page 5Linked to original sources

[Hemoglobin, hematocrit, lactates and glucose in blood of fattening pigs in the course of slaughering and snout loop fixation].

Blood was sampled from fattening pigs fixed with the snout loop in the pen as well as during slaughter after control or container transport. Assays were made of haemoglobin (Hb), haematocrit (Hk), glucose concentration (PG), and lactic acid (MS) in the plasma. The mean values and standard deviations of Hb and Hk were 13.97 +/- 1.14 g/100 ml, 48.36 +/- 3.67 per cent, 15.24 +/- 1.12 g/100 ml, 49.83 +/- 4.04 per cent, 15.32 +/- 1.23 g of 100 ml, and 51.08 +/- 3.73 per cent. The means values of PG were between 51 and 101 mg of 100 ml and those of MS between 8 and 16 mMol/l.

Abattoirs↗

[Influence of blood volume drain on some factors of circulation in rabbit].

Blood volume were drained from 20 female rabbits, all White New Zealanders, 2.5 kg in average body weight. Several factors of their circulation were determined twice, prior to and after the blood volume withdrawals. Included in the tests were haematocrit, haemoglobin, plasma volume by means of Evans blue dye dilution technique, and blood volume. The amounts of blood volume, BV0, drained ten, 20, 40, 60, and 70 minutes after beginning of the experiment were 4.4, 6.7, 8.9, 11.2, and 13.4 per cent. The ambient temperature was 15 degrees C and the relative humidity 60 per cent. The haematocrit value dropped to 91.2 per cent of the original figure over the whole experimental period and haemoglobin to 87.5 per cent, but decline of the latter was of minor importance along with blood volume loss from 8.9 per cent to 11.2 per cent BV0. Blood volume drain of 8.9 per cent BV0 was accompanied by 102.04 per cent plasma volume, PV0, and 100.4 per cent BV0. Erythrocyte volume and total haemoglobin exhibited similar behaviour in connection with the above amount of blood drain and did not return to their original values. Rabbit response to blood loss (re-absorption of fluid and splenic depletion) is discussed.

Animals↗

[Reactions of European wild boars (Sus scrofa scrofa L.) to running stress. 1. Behavior of respiratory and heart rate as well as the rectal temperature in standard tests of varying intensity and duration].

Eight wild boars, aged between twelve and six months and weighing between 81 kg and 39 kg, all kept on floor surfaces and diets used also for domestic pigs, were exposed on a horizontally operated belt to three locomotor stresses which differed by intensity and duration. The speeds were 78 m/min in tests A and C and 138 m/min in test B. The time was limited to ten minutes in test A and 40 minutes in test C, whereas in test B the animals were kept running their rectal temperature had gone up to 41.5 degrees C. Rectal temperature, heart rate, respiratory frequency, as well as the electric diastole-systole quotient were measured in each of the tests. Described are the effects of both intensity and duration in terms of disturbance of the physiological equilibrium. The response produced by wild boar were compared with those recorded from domestic swine and yielded only slight superiority in physical fitness of wild boar.

Animals↗

[Reactions of European wild boars (Sus scrofa scrofa L.) to running stress. 2. Circulation values, blood glucose and lactates and blood acid-base status].

Four female and four male wild boars, 63.8 +/- 4.43 kg in live weight, were exposed to locomotor stress on a horizontally operated belt set to a speed of 2.5 m/s for ten minutes. The ambient temperatures were between 12 degrees C and 18 degrees C and the relative humidities between 55 and 75%. The following parameters were measured prior to, during, and after the stress tests: rectal temperature, haemoglobin level, haematocrit, plasma and blood volumes, total haemoglobin levels, lactic acid and glucose levels in blood plasma, pH, pCO2, and excess base. Rectal temperatures went up continuously. Haemoglobin levels, blood volumes, haematocrit values, and total heamoglobin were increased due to the mobilisation of erythrocytes from the spleen. The plasma volume remained constant. Lactic acid went up at the beginning of the stress run and declined during running. Respiratory alkalosis occurred in the context of the acid-base state prior to, towards the end, and even more after stressing.

Acid-Base Equilibrium↗

The radiologic diagnosis of malignant tumors of the larynx.

A variety of radiologic examinations are used to assess malignant tumors of the larynx. The primary role of radiographic examination is the pretreatment classification of laryngeal cancer, necessary to select the appropriate modality of treatment. The major radiologic modalities comprise conventional lateral radiography, anterior-posterior tomography, laryngography, xeroradiography, and high KV selective filtration radiography. Advanced radiologic modalities such as CT scanning and transverse B-mode gray scale ultrasound may also prove useful. It is the purpose of this presentation to define the role of these modalities in pretreatment definition of laryngeal cancer. Additionally, some comment is made as to the role of radiology in the diagnosis of post-radiation therapy recurrence of laryngeal cancer.

Adult↗

[Effect of anemia on various reactions of the domestic swine due to physical exertion. I. Initial values and characteristics of anemia].

In six anaemic and six healthy pigs at rest the following values were determined:--rectal temperature, heart rate, respiratory rate, haemoglobin (Hb), haematocrit (Hk), total haemoglobin (THb), plasma volume, blood volume, plasma osmolarity, lactic acid and glucose content of plasma, blood pH, carbon dioxide tension and base excess. There were significant differences between anaemic and normal pigs in Hb, THb, relative THb, Hk, mean cell haemoglobin concentration, lactic acid content; in the ECG there were differences in QT and ST intervals and the ratio of diastole to systole.

Anemia↗

[Effect of anemia on various reactions of the domestic swine due to physical exertion. 2. Components of cardiovascular function and body temperature].

The following measurements were made in six anaemic and six healthy pigs during and after physical exertion on a belt moving at 70 m/min for 10 minutes at environmental temperature of 22-24 degrees C and relative humidity of 55-65%:--rectal temperature (RT), heart rate, total haemoglobin, plasma volume (PV), blood volume (BV) and plasma osmolarity (PO). The increase: in RT and PO, heart rate during exercise, respiratory rate after exercise, and the fall in PV and BV during exercise as well as changes in erythrocytes were all more pronounced in anaemic pigs than in healthy pigs.

Anemia↗

[Effect of anemia on various reactions of the domestic swine due to physical exertion. 3. Changes in plasma glucose and lactic acid concentrations].

Six anaemic and six healthy pigs were exercised for ten minutes on a belt moving at 78 m/min. Initial blood glucose values in healthy pigs averaged 71.2 mg/100 ml, and they changed very little during and after exercise. Initial values were similar in anaemic pigs (70.7 mg/100 ml), but they increased continuously, during exercise, reaching a peak of 157.4 mg/100 ml one minute after the end of exercise. Blood lactic acid increased from 1152 to 2463 mmol/litre in healthy pigs during the first minute of exercise, and then fell gradually. In anaemic pigs it increased from 1652 to 8478 mmol/l during the ten minutes of exercise, and then fell gradually. Correlations between lactic acid and haemoglobin content, between rectal temperature and Hb, and between lactic acid and changes in rectal temperature were discussed.

Anemia↗

[Effect of anemia on various reactions of domestic swine due to physical exertion. 4. Changes of serum acid-base equilibrium].

Carbon dioxide tension, pH and the excess of base were determined in blood samples obtained from the posterior vena cava of six healthy and six anaemic pigs subjected to ten minutes of exercise on a belt moving at 78 m/min at 22-24 degrees C and relative humidity of 55-65%. The fall in these values during physical exertion was greater in anaemic than in healthy pigs. The roles of buffering capacity and rise in body temperature, and the relationship between blood lactic acid and base excess were discussed.

Acid-Base Equilibrium↗

[Evaluation of blood glucose concentration during exertion. 6. Effect of anemia on the glucose regulation capacity of domestic swine in standardized running exercise].

Individual mean blood glucose values and the scatter of individual values were determined in six healthy and six anaemic pigs before, during and after ten minutes of exercise on a belt moving at 78 m/min (environmental temperature 22-24 degrees C, relative humidity 55-65%). The glucose regulatory capacity of anaemic pigs was inferior to that of healthy pigs. Blood glucose regulation was related to haemoglobin content and to the increase in rectal temperature during exercise.

Anemia↗

[Lactic acid content of blood plasma in domestic swine of various breeds during physical exertion].

Lactic acid was determined by an enzymic method in plasma samples taken from 20 pigs of the German Edelschwein, German Landrace, German Saddleback and Edelschwein/Landrace crosses before, during and after being made to run on a band moving at 1.3 metres/second for ten minutes, at 10 degrees C and relative humidity of 65-75%. A special method was used to assess the degree of exertion. The lactic acid curve showed that Edelschwein and German Saddlebacks had a low regulatory capacity while German Landrace and the crossbred pigs had a large capacity. For assessing differences attributable to individuals or to breeds, the occurrence of the maximum lactic acid concentration during or after exercise was of special significance.

Animals↗

[ Glucose concentration in blood during exertion. 5. Use of the total distribution of blood glucose values during physical exercise or the estimation of response to exertion in various breeds of swine].

Blood glucose was determined by an enzymic method in 56 pigs of the German Edelschwein, German Landrace, German Saddleback breeds and Edelschwein/Landrace crosses before, during and after exercise on a belt moving at 1.3 metres/second for ten minutes, at 10 degrees C (winter) or 22-34 degrees C (summer) and relative humidity of 65-75%. Total plasma glucose was calculated from the plasma volume. Total scatter of values for blood glucose concentration and total plasma glucose was greater in Edelschwein and Saddlebacks than in Landrace and the crossbred pigs. There was a close and significant relationship between individual regulatory capacity and breed. The total scatter of blood glucose values was greater in winter than in summer.

Animals↗

[Effect of the type of management and training on heart rate, rectal temperature and respiration rate of domestic swine during physical exertion].

29 pigs (meat type of German Landrace) were kept in groups in a confined space (0.48 m2 a head; group E), in a normal area (1.2 m2 a head; group N) or in a normal area plus daily exercise (group L). After having been kept under these conditions for specified periods, the pigs were made to run on a band moving at 1.1 metres a second for 2 km. During exercise the heart rate increased to 275 beats a minute in group E and only 180 in group L. In group L the recovery pulse rate was greater and the absolute and relative heart weight smaller than in group L; rectal temperature after exercise was also higher than in group L. Values for group N lay between those of groups E and L. The relationship of respiration rate to rectal temperature after exercise was greater in group L than in groups E and N. Physical fitness of groups E and N was inferior to that of group L.

Animal Husbandry↗

[Evaluation of the ability to regulate blood volume under standardized motoric stress].

Sixteen German Landrace pigs of the meat type were kept in individual cages (0.47 m2 floor area each) or in two pens of four pigs providing 1.05 m2 per animal, under otherwise identical conditions for 45 days, commending at a body weight of 45 kg. Plasma volume and plasma glucose were determined before, during and after the pigs made to run on a band moving at 1 m/s for 20 minutes at 24 degrees C. Changes in plasma volume were studied from the total scatter of values (total area covered by the curve of values). This made it possible to quantify individual regulatory capacity and the influence of management. Close confinement in an individual cage reduced the regulatory capacity of the plasma volume by 3.5 to 4 times. There were significant qualitative and quantitative relationships between intravascular fluid volume and intravascular glucose or glucose concentration.

Animals↗