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Biomedical subjects

M T Aznabaev

Publications and source records attributed to M T Aznabaev.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Use of instenon in complex treatment of patients with optic nerve atrophy caused by craniocerebral trauma].

Instenon, a combined nootropic agent, was used on the step-type basis within a complex treatment of optic nerve atrophy caused by craniocerebral trauma. Our study revealed that instenon, when used within a complex treatment of a partial optic nerve atrophy caused by craniocerebral trauma, improved the visual acuity in 85.7% of patients and it expanded the total visual field in 76.2% of patients, whereas the routine therapy ensured the related improvements in 58.9% and 61.5% of patients, respectively. Besides, the drug provided for a better retinal electric sensitivity and for a better optic nerve conduction in 73.8% of cases versus 64.1% of cases with basic therapy. Increased velocity parameters in the ocular-artery blood flow were registered in 77.1%, of patients who received instenon, by duplex scanning.

Adolescent↗
PubMedDate not supplied

[Changing electrophysiological parameters in the eye in children with insulin-dependent diabetes mellitus].

Fifty-eight (58) children with insulin-dependent diabetes mellitus (IDDM) were examined and shared between 6 groups: Group 1--primarily diagnosed diabetes mellitus (DM); Group 2--DM with an up to 5-year history; Group 3--DM with a an up to 10-year history; Group 4--children with non-proliferative diabetic retinopathy; Group 5--children with diabetic cataract. Forty-five healthy children were in the control group. According to the pattern registration of visual induced potentials (RVIP), a reliable prolongation of latency P100 was detected in children of Groups 1 and 4. The results of the general electroretinography (ERG) showed a reliably decreased amplitude of the basic wave b- in Groups 1-4 and an increased amplitude of wave a- in Groups 4 and 5. According to photopic ERG, a reliably decreased amplitude of wave a- was detected in Groups 1-5 and a decreased amplitude of wave b- was registered in all groups except for Group 2. Scotopic ERG showed, in Group 5, an increased amplitude of wave a- (p < 0.05) at the normal values of wave b-, and, in Groups 1-4,--a significantly inhibited amplitude of wave b-. Finally, rhythmic ERG showed a reliably inhibited amplitude in all groups.

Adolescent↗
PubMedDate not supplied

[Experimental implantation of the "Ufalens" artificial lens in primary surgical treatment].

Described in the paper is the response of eye tissues in extraction of traumatic cataract with IOL implantation observed in primary surgical treatment of penetrating corneal wounds. Experiments were made on 60 rabbits (120 eyes). 5 mm-long penetrating corneal wounds located in the optic zone with damaged lens were modeled in the experimental group (30 rabbits, 60 eyes). The wound was surgically treated in 24 hours: traumatic cataract was extracted and posterior-chamber IOL was implanted ("Ufalens-1" manufactured at the UFA Research institute of eye diseases). Thirty rabbits (60 eyes) were in the control group: transparent lens was extracted in them and IOL (same model) was implanted. The animals were taken out of the experiment by air embolism on days 3 and 7 and in 1, 3 and 7 months. Tinting with hematoxylin or eosin was used to ensure plain histological examination. The stages of histological treatment of tissues were carried out according to the standard method. A conclusion was made on the basis of research results that the implantation of "Ufalens-1" in primary surgical treatment of eyeball wounds with damaged lens does not have any essential clinical or morphological impact on the severity of the postoperative period and can be recommended as a method of medical rehabilitation of victims for use at specialized ophthalmologic clinics.

Animals↗
PubMedDate not supplied

[Results of primary IOL implantation after extraction of congenital cataract in two-year babies].

The results of aspiration of congenital cataract and those of IOL implantation were analyzed for 15 children (17 eyes) aged 2 years or less. The specificity of the postoperative clinical course after implantation of different IOL types and of changes of refraction as well as peculiarities of the growth of the aphakic eye in unilateral cataract versus its match were analyzed. Exudative reaction, stages I-II, is the main problem encountered in the early postoperative period irrespective of a type of the implanted IOL. Implantation of rigid IOLs is associated with a higher risk of development of secondary cataract in the late postoperative period. The postoperative changes of refraction do not depend on an IOL type. The artiphakic eye becomes myopic as the anatomic-optic parameters of the growing eye change. There are no reliable differences between the growth indices in the anterior-posterior axis of the artiphakic and growing eyes.

Cataract↗
PubMedDate not supplied

[Diagnosis and treatment of children with acute inflammatory diseases of the orbit].

The role of computer tomography within the differential diagnosis of acute inflammatory lesions of orbit tissues as well as an appropriate tactics of treatment were evaluated. Computer tomography, "Somafom AR-T", 512 x 512 pix matrix, Siemens (Germany), was made in the axial and coronary projections to delineate the inflammatory zone. The findings of computer tomography denoted explicitly the spatial features of pathology within the orbit with anatomic structures. In periostitis and reactive edema in retrobulbar fat of the orbit, the treatment of patients was conservative made jointly with otolaryngologist. Orbitotomy with drainage or with lancing of affected sinuses was made in abscess and phlegmon of the orbit. There was a complete recovery in a majority of patients with acute diseases of the orbit; they preserved their functions of the organ of vision and of its appendages. Therefore, computer tomography is a valuable and highly effective examination tool within the differential diagnosis of acute inflammatory diseases of the orbit. The diagnosis and treatment of such diseases call for a board of doctors including ophthalmologist, otolaryngologist and oral surgeon.

Abscess↗
PubMedDate not supplied

[Results of surgical treatment for cataract with implantation of intraocular lenses in children with insulin-dependent diabetes mellitus].

Primary implantation of intraocular lenses (IOLs) was made in 9 children (16 eyes) after removal of cataract; secondary implantation was performed in 2 children (4 eyes) 3 and 4 years after diabetic cataract aspiration. After surgery, 4, 4, and 3 children were followed up 1, 2, and 3 years, respectively. Thirteen cases of secondary cataract were observed after primary implantation (16 eyes); secondary cataract was recorded in 100% of cases after implantation of polymethyl methaacrylate IOLs and hydrophilic "Centrflex" lenses and only in 57.1% after implantation of hydrophobic "Acrysof" lenses. The visual acuity was 0.48 +/- 0.14 after removal of secondary cataract and 0.88 +/- 0.11 after laser discission. Laser invention did not lead to the progression or occurrence of diabetic retinopathy (DR) in the late periods of a follow-up. Cataract removal with IOL implantation in children with insulin-dependent diabetes (IDD) yields high functional results. The postoperative follow-up did not demonstrate a significant increase in the severity and incidence of DR, which seems to be associated both with a good postoperative IDD compensation and preventive treatment. The use of the hydrophobic flexible lenses is more optimal to prevent the development of secondary cataract.

Adolescent↗
PubMedDate not supplied

[Comprehensive ultrasound diagnosis of orbital tumors and preudotumors].

A comprehensive ultrasound examination was made in 37 patients with orbital tumors and pseudotumors. The basic differential diagnostic sonographic and Doppler signs were defined in capillary hemangioma, vasculitis at the stage of infiltration and malignancies of the orbit.

Diagnosis, Differential↗
PubMedDate not supplied

[Experimental determination of a safe dose of the enzyme collagenase agent for subconjunctival and retrobulbar administration].

The authors carried out two series of experiments using 32 eyes of 16 rabbits. The enzyme collagenase agent was daily injected, by increasing doses up to 25, 50, 75, and 100 units for subconjunctival ocular (Series 1) and retrobulbar (Series 2) injections. The control groups included 3 rabbits in both series (6 eyes). They were injected 0.5 ml of isotonic sodium chloride solution. It has been concluded that the safest doses of collagemase are 25-50 units for subconjunctival and retrobulbar injection.

Animals↗
PubMedDate not supplied

[Changes in parameters of the eyeball during the 1st year of life].

The authors have examined the eyes in a group of healthy full-term infants during the first year of life. Anatomic and optic parameters of the eyes of newborns aged 2 hrs to 7 days and 1-year-old infants were under study. The data are important for ophthalmic surgery of infants of this age group.

Adult↗
PubMedDate not supplied

[The role of early contact lens correction in the rehabilitation of nursing infants with aphakia].

The authors analyze the results of early (on days 5-8 postoperation) contact correction with soft contact lenses (SCL), carried out in 126 infants (206 eyes), operated on for congenital cataract extraction at the age of 2-12 mos. Soviet IOZM, Czechoslovak Spofa-lens, and American Bausch and Lomb lenses have been applied for 18-14 hrs daily, in parallel with the treatment for amblyopia (direct occlusion, a total exposure of the retina), carried out at home. A thorough adaptation, observance of the hygiene and schedule of the lens use have been a guarantee of the absence of ocular complications. SCLs considerably improve the vision acuity and are recommended for early correction of aphakia after congenital cataract extraction, carried out during the first months of infant life.

Aphakia, Postcataract↗
PubMedDate not supplied

[Effect of early surgery in treating congenital cataracts on the growth of the eyeball in nursing children].

Echobiometry of 24 eyes operated on for congenital cataracts has been carried out. The infants' ages varied from 4 to 6 months. 23 children (43 eyes) have made up the peference group. The measurements have been carried out in 6-7, 10-12, and 24-26 months after surgery. The results evidence no relationship between early cataract extraction and the growth of the anteroposterion axis of the eye in infants.

Cataract↗