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Biomedical subjects

M Vandendris

Publications and source records attributed to M Vandendris.

At least 19 recordsLinked to original sources

[Multilocular cystic nephroma in adults. Unusual presentation and review of the literature].

The authors report a case of a multilocular cystic nephroma in an unusual site, extensively invading the pelvis and causing atypical symptoms of acute lumbar pain. The authors discuss the confusing terminology, the unusual presentation of this cystic tumour and the difficulty of establishing a definitive diagnosis of its benign nature before the operation in the light of a brief review of the literature.

Female↗

Radiologic investigation of renal colic: unenhanced helical CT compared with excretory urography.

OBJECTIVE: Our aim was to compare unenhanced helical CT and excretory urography in the assessment of patients with renal colic. SUBJECTS AND METHODS: Fifty-three of 70 consecutive patients with acute signs of renal colic were prospectively examined with unenhanced helical CT, which was followed immediately by excretory urography. Two radiologists who were unaware of the findings independently interpreted these examinations to determine the presence or absence of ureteral obstruction. On all CT scans that had positive findings for ureteral stones or obstruction, we looked for secondary signs of obstruction (perinephric or periureteral fat stranding, ureteral wall edema, ureteral dilatation, and blurring of renal sinus fat). RESULTS: A stone was recovered in 45 of the 53 patients, nine before and 36 after imaging. The latter 36 patients had their stones identified on CT, whereas only 24 patients had their stones identified on excretory urography. Eight patients without stone disease had normal ureters on both CT and excretory urography. Of the 45 patients who had stone disease, 26 had ureteral dilatation on both CT and excretory urography, and 36 patients who recovered a stone after CT had secondary signs of obstruction. Of the nine patients who recovered a stone before CT, three had secondary signs of obstruction. Two patients had periureteral fat stranding, ureteral wall edema, and renal sinus fat blurring. One patient had only ureteral wall edema. CONCLUSION: Compared with excretory urography, unenhanced helical CT is better for identifying ureteral stones in patients with acute ureterolithiasis. Secondary CT signs of obstruction, including renal sinus fat blurring, were frequently present even when the stone was eliminated before imaging.

Acute Disease↗

[Comparison of spiral computed tomography without contrast media and intravenous urography in the diagnosis of renal colic].

OBJECTIVES: This prospective study was designed to determine the reliability of noncontrast spiral CT scan, compared to that of intravenous urography (IVU), in the diagnostic assessment of acute renal colic. MATERIAL AND METHODS: 53 patients, admitted with an empirical diagnosis of renal colic after initial assessment, were included and underwent spiral CT scan without contrast agent injection, immediately followed by IVU. These examinations were performed according to a blind protocol by two different radiologists. We initially looked for the presence of stones and/or urinary tract obstruction. Patients with a stone and/or obstruction (urinary tract dilatation) visible on CT scan were then examined for the presence of CT signs associated with stone disease (infiltration of the perirenal and periureteric fat, oedema of the ureteric wall and loss of sinus fat). We calculated the statistical correlation between the presence or absence of obstruction and these accessory signs. RESULTS: 45 stones were recovered (in 36 cases before the two examinations). 36 stones were identified on CT versus only 24 on urography. Urinary tract dilatation was demonstrated in 26 out of 53 cases by both urography and CT. The frequency of accessory signs visible on CT in the presence of stones (n = 36) was 66% for infiltration of periureteric fat, 36% for infiltration of perirenal fat and 75% for oedema of the ureteric wall. In the presence of urinary tract dilatation, these frequencies were 92%, 84% and 60% respectively. CONCLUSION: Noncontrast spiral CT is a reliable and rapid diagnostic modality for the detection of urinary stones, providing a morphological study equivalent to that of IVU and able to guide appropriate treatment. It should replace IVU in the diagnostic assessment of renal colic.

Acute Disease↗

Megalourethra and abnormalities of the cavernous bodies: cause of erectile dysfunction.

Megalourethra is a nonobstructive urethral dilatation associated with poor embryogenic development of the corpus spongiosum and occasionally with maldevelopment of the cavernous bodies. The two entities are distinguished arbitrarily: the scaphoid and the fusiform type. Although megalourethra may be an isolated entity, the association with concomitant upper urinary tract abnormalities is rather frequent. Appropriate investigation of the urinary tract is indicated in all patients presenting this urethral anomaly. We describe the case of a 24-old man complaining of erectile dysfunction due to enlarged corpora cavernosa associated with megalourethra. The penile circumference upon erection made vaginal intromission complicated. Surgical correction based on the Nesbitt technique was performed. The postoperative result is satisfactory and normal sexual life is reported.

Adult↗

Belgian multicenter clinical study of alfuzosin, a selective alpha 1-blocker, in the treatment of benign prostatic hyperplasia. The Alfuzosin Belgian Group.

The effects of alfuzosin, a potent alpha 1-blocker, were assessed in patients with benign prostatic hyperplasia, in a double-blind, multicenter, placebo-controlled, cross-over study. Treatment duration was 4 weeks for both alfuzosin and placebo. A significant beneficial effect of alfuzosin (7.5 to 10 mg a day) on clinical subjective and objective criteria was observed as compared to placebo: total Boyarsky score decreased by 1.63 points, peak urinary flow improved by 2.03 ml/sec. Alfuzosin was well tolerated, the observed adverse events corresponded to the pharmacological properties of this compound, and resolved rapidly.

Adrenergic alpha-Antagonists↗

Surgical approach of venous leakage.

Venous leakage is a cause of impotence easily demonstrated by dynamic cavernosography. It revealed dorsal venous leakage in 41 patients, perineal leakage in 15 patients and dorsal plus perineal leakage in 42 patients. Dorsal vein ligation was performed in 38 cases. Fourteen patients underwent ligation of crura penis. Combined procedure was done in 36 patients. Immediate results of the surgical approach are quite encouraging, but finally, they are satisfactory in only 20% of the cases. Nevertheless, surgical treatment of venous leakage can further be taken into consideration to reduce blood outflow and strengthen vasoactive drug effects.

Adult↗

Treatment of pharmacological priapism with phenylephrine.

Pharmacological prolonged erections or priapism due to anesthesia were treated in 36 patients with intracorporeal injections of phenylephrine. Detumescence was obtained rapidly in every case and no marked side effect was reported. Considering the possible toxicity of other adrenergic agents, phenylephrine is strongly recommended in the treatment of priapism.

Adult↗

[The effects of mepartricin on the symptomatology of prostatic hypertrophy--double-blind controlled trial].

Seventy one patients were treated with mepartricin or placebo in three urological centres for a mean duration of 102 days (extremes: 60 and 142 days). An analysis of the results was carried out for 34 patients in the placebo group and 36 patients in the mepartricin group. The results indicate a significant improvement in both the placebo group and the mepartricin group. The irritative and obstructive symptoms are improved in the active treatment group with a response rate of the order of 70%, compared to approx. 45% in the placebo group. An improvement of the values on the flow meter, though not statistically significant, is observed following treatment with mepartricin, compared to the placebo group. There were no significant differences in the evolution of the prostate gland volume, determined by ultrasound in the placebo group and the active treatment group. Side-effects were minor and only one patient reported epigastric pain.

Aged↗

[The treatment of prolonged erections using phenylephrine].

Phenylephrine was used intracavernously to treat prolonged erections in 38 cases. A rapid detumescence was obtained in every case. Phenylephrine seems to be superior to all other adrenergic drugs in reason of its rapid action and its lack of side effects.

Adult↗

[Acute urinary retention secondary to cavernous metastases from a prostatic tumor].

Prostatic carcinoma metastatic to the penis is a rare phenomenon. We report two cases of acute urinary retention due to penile metastases from a prostatic carcinoma. Patients may have a penile mass or diffuse swelling of the penis. Some patients develop priapism and urinary retention can be rarely observed. The most effective treatment seems to be local excision with wide resection and, if necessary, total penectomy. The prognosis remains poor regardless of the type of therapy employed.

Adenocarcinoma↗

Giant leiomyoma of the kidney.

A rare case of giant renal leiomyoma presenting as a suprarenal mass is reported. This type of tumor seldom gives rise to other clinical symptoms. The angiographic appearance has no characteristic features. The treatment of choice is nephrectomy since it is impossible to make a correct preoperative diagnosis.

Adult↗

Abscess of corpus cavernosum.

A rare case of abscess of the corpus cavernosum is described. The patient was treated successfully by surgical drainage and antibiotic therapy. A right penile deviation and a relatively poor erection were reported by the patient 6 weeks postoperatively but he did not require further surgery. The possible causes, diagnosis and treatment of this rare disease are discussed.

Abscess↗

Treatment of impotence due to perineal venous leakage by ligation of crura penis.

Perineal venous leakage is a cause of impotence that is demonstrated easily by dynamic cavernosography. Perineal ligation of the crura penis was done in 13 patients with this type of impotence. Nine patients achieved satisfactory intercourse and 3 had sufficient erection after intracavernous self-injections of papaverine. Implantation of a penile prosthesis was required in only 1 patient. Ligation of the crura penis is a simple operation that seems to be efficient in the treatment of impotence owing to perineal venous leakage.

Adult↗