Biomedical subjects

Malik Hellal

Publications and source records attributed to Malik Hellal.

2 recordsLinked to original sources

PubMed2006

Microwave-assisted cyclic amidine synthesis using TiCl4.

Microwave-assisted treatment of various heterocyclic amides (benzodiazepinone, phthalazone) with TiCl(4) in the presence of primary or secondary amines provides the corresponding amidines. In addition to the interest of the microwaves for this reaction, our study highlights the higher reactivity of the cyclic acetamide moiety compared to the cyclic benzamide moiety towards this TiCl(4)-mediated reaction.

Amidines↗

PubMed2005

Synthesis of a photoactivatable probe of the anandamide re-uptake.

To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anandamide transport process.

Arachidonic Acids↗