Biomedical subjects

Meijuan Meng

Publications and source records attributed to Meijuan Meng.

4 recordsLinked to original sources

PubMed2003

[HRCT imaging characterized of congenital abnormalities of the inner ear in 45 cases].

OBJECTIVE: To explore the high resolution CT (HRCT) image characterized of congenital abnormalities of the inner ear(CAIE), and its value in the diagnosis and treatment of CAIE. METHOD: The clinic data and axial HRCT scans of CAIE in 45 cases were analyzed. RESULT: In 45 CAIE patients, most of them were frequently associated with slowly progressive sensorineural hearing loss in childhood, 15 ears were fluctuating hearing loss. Seventeen ears were unilateral semicircular canal paralysis. HRCT showed that Michel type 3 cases(4 ears), Mondini type 25 cases(39 ears). Large vestibular aqueduct malformation not associated with anomalies of inner ears 13 cases(23 ears), anomalies of internal auditory canal 4 cases (5 ears). Thirteen ears were associated with outer and middle ear malformation. CONCLUSION: HRCT image has the important value in the diagnosis and treatment of CAIE, especially for the excerpt of indication of cochlear implantation.

Adolescent↗

PubMed2003

[The influence of botulinum toxin type A on vasomotor rhinitis and morphological study].

OBJECTIVE: To investigate the effect and mechanisms of botulinum toxin type A(BTA) on vasomotor rhinitis. METHOD: A retrospective study of 32 patients with vasomotor rhinitis who received BTA injection at 4 points in bilateral nasal cavities with 2.5 units at each point had been done. The state of rhinorrhea, nasal obstruction, sneeze and nasal mucosa edema of each patient were recorded and scored before and after the application of BTA respectively with follow-ups of 6-30 months. Twelve guinea pigs were randomly divided into 2 groups: BTA group and control group. Merocel sponge soaked with 10 units (0.2 ml) BTA was put into left nasal cavity under general anesthesia for one hour in BTA group. Saline replaced BTA in control group. The inferior turbinate mucosa of guinea pig ware harvested under general anesthesia at 7, 14, 28 days after BTA treatment and was observed with HE staining and electron microscope. RESULT: Rhinorrhea improved significantly in all 32 patients while sneeze, nasal obstruction and mucosa edema reduced partly. The reducing of rhinorrhea lasted averagely 6 weeks. Twelve patients had an episode of nasal dryness or increased rhinorrhea at the day of injection. No other complications were found. Seven, fourteen days after local BTA application, the degenerations of glandular epithelium and canal epithelium were observed in nasal mucosa of guinea pigs. Most of the glandular cells showed normal at 28 days after BTA treatment. CONCLUSION: BTA can induce the degeneration of glandular cells in nasal mucosa and thus obviously relieve over rhinorrhea of patients with vasomotor rhinitis.

Adult↗

PubMed2002

[Dyspnea analyse and treatment to adult acute epiglottitis].

OBJECTIVE: To discuss the estimation and treatment of adult acute epiglottitis dyspnea. METHOD: 126 adult with acute epiglottitis patients were analyzed. RESULT: None of 30 patients undergone epiglotiotomy had asphyxia, inflammation diffuse or serious hemorrhage. 8 patients undergone tracheotomy, one patient undergone thyroericotomy but died. One of 87 patients with conservative treatment died. CONCLUSION: Gaspping, salivating and dyslogia are symbols of severe larynx obstruction. Fibrous laryngoscope is the best way of examine. Keeping respiratory path open and eliminating epiglottis swelling is the key of treatment.

Acute Disease↗

PubMed2002

[Auditory neuropathy].

OBJECTIVE: To explore the clinical and auditory functional feature of auditory neuropathy(AN). METHOD: The clinic signs, audiometric test and electrophysiology were analyzed on 54 cases of AN. RESULT: 70 ears had low frequency pure tone hearing loss. 24 ears had cover basic hearing threshold. 6 ears had flat hearing threshold. 4 ears showed high frequency hearing loss. The average low-frequency, median-frequency and high-frequency hearing threshold were 67.63 +/- 15.30, 43.61 +/- 16.28 and 32.25 +/- 14.80 dB HL respectively. The tympanograms are normal. 77 ears lost acoustic reflex. 31 ears increased acoustic reflex threshold. All of them induced no ABR and had normal DPOAE with 26 cases' contralateral acoustic suppression uninfluenced. 16 cases had controversial pure tone threshold compared with speech discrimination. 23 had normal temporal bone CT image or MRI. 10 cases accompanied with peripheral neuropathy. CONCLUSION: Abnormal ABR, normal DPOAE, unparallel pure tone threshold to speech audiometry, loss of stapedial acoustic reflex and OAE contralateral acoustic suppression, loss of the pure tone threshold primarily in low-frequency SNHL are the important features of AN, which shows that the lesioned site may lie at the intracochlear acoustic nerve. It is necessary to differentiate it from the common SNHL and central nerve hearing loss.

Acoustic Impedance Tests↗