PubMed Health⌕ Search

PubMed · 15515556

[Auditory neuropathy].

Abstract

OBJECTIVE: To explore the clinical and auditory functional feature of auditory neuropathy(AN). METHOD: The clinic signs, audiometric test and electrophysiology were analyzed on 54 cases of AN. RESULT: 70 ears had low frequency pure tone hearing loss. 24 ears had cover basic hearing threshold. 6 ears had flat hearing threshold. 4 ears showed high frequency hearing loss. The average low-frequency, median-frequency and high-frequency hearing threshold were 67.63 +/- 15.30, 43.61 +/- 16.28 and 32.25 +/- 14.80 dB HL respectively. The tympanograms are normal. 77 ears lost acoustic reflex. 31 ears increased acoustic reflex threshold. All of them induced no ABR and had normal DPOAE with 26 cases' contralateral acoustic suppression uninfluenced. 16 cases had controversial pure tone threshold compared with speech discrimination. 23 had normal temporal bone CT image or MRI. 10 cases accompanied with peripheral neuropathy. CONCLUSION: Abnormal ABR, normal DPOAE, unparallel pure tone threshold to speech audiometry, loss of stapedial acoustic reflex and OAE contralateral acoustic suppression, loss of the pure tone threshold primarily in low-frequency SNHL are the important features of AN, which shows that the lesioned site may lie at the intracochlear acoustic nerve. It is necessary to differentiate it from the common SNHL and central nerve hearing loss.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Jinling Wang, Lei Gao, Fei Xue, Meijuan Meng, Dingjun Zha, Yaozhu Deng. 2002. [Auditory neuropathy].. https://pubmed.ncbi.nlm.nih.gov/15515556/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Behavioral audiometry: validity of audiometric measurements obtained using the "Delaroche protocol" in babies aged 4--18 months suffering from bilateral sensorineural hearing loss.

OBJECTIVE: Evaluation of the validity of the audiometric measurements obtained in babies aged from 4 to 18 months suffering from bilateral sensorineural hearing loss (SNHL) using an original behavioral audiometry (BA) protocol called the "Delaroche protocol" [IJPORL 68 (2004) 1233-1243]. METHODS: (1) We compared the auditory brainstem (ABR) threshold in the better ear with the mean of the BA thresholds obtained, bilaterally, at 2000 and 4000 Hz, both measurements being performed in the diagnostic phase. (2) We compared the BA thresholds obtained prior to the age of 18 months, bilaterally, at the frequencies of 500,1000, 2000 and 4000 Hz, with the thresholds of the better ear obtained at the same frequencies at the age of 3--4 years by BA. RESULTS: (1) Cross- sectional study (78 children). When there was no ABR at 100 db, there was no BA response at 100 dB in 84.2% of cases, resulting in a kappa coefficient of 0.72. When there were ABR, the difference between the ABR and the BA thresholds was equal to or less than 10 dB in 67% of cases and equal to or less than 20 dB in 95% of cases. (2) Longitudinal study (50 children). The difference between the behavioral thresholds obtained within 4 and 18 months (median age=12 months) and those obtained at 3 or 4 years old in the same children (median age=39 months) was equal to or less than 10 dB in 94% of cases at the frequencies of 1000, 2000 and 4000 Hz and in 78% of cases at 500 Hz. CONCLUSION: The two analysis evidence the validity of the behavioral measurements obtained at an early age using the protocol described.

Acoustic Impedance Tests↗

Changes in otoacoustic emissions and high-frequency hearing thresholds in children and adolescents.

With the aim of characterizing the loss of high frequency hearing sensitivity in children, hearing thresholds and otoacoustic emissions were measured in a group of 126 normal hearing children and adolescents aged from 6 to 25 years. The subjects were divided into four 5-year age groups. Hearing thresholds over a range of 125 Hz-12.5 kHz were similar in all age groups, the average hearing threshold at 16 kHz was significantly elevated in the oldest age group. The response values of transiently evoked otoacoustic emissions (TEOAEs) significantly declined with age; the decline was negatively correlated with the hearing loss at 16 kHz. Significantly larger TEOAE responses and average distortion-product otoacoustic emission (DPOAE) values at 6.3 kHz were present in the youngest group in comparison with the other three older groups. Spontaneous otoacoustic emissions (SOAEs) were present in 70.8% of the children (in either one or both ears) with the greatest prevalence in the 11-20-year-old subjects. In the 21-25-year-old group, the hearing loss at 16 kHz was significantly smaller in ears with SOAEs than in ears without SOAEs. The results demonstrate that the increase in the high frequency hearing threshold at 16 kHz, which starts at ages over 20 years, is correlated with a decrease in the TEOAE responses at middle frequencies.

Acoustic Impedance Tests↗

Relationship between transducer type and low-frequency hearing loss for patients with ventilation tubes.

OBJECTIVE: To determine the relationship between the type of transducer used to perform pure-tone audiometry and the appearance of low-frequency hearing loss at 250Hz and 500Hz for patients with ventilation tubes. METHODS: Air conduction thresholds at 250Hz and 500Hz were measured using Telephonics TDH-49 supra-aural headphones and EARTONE 3-A insert earphones for patients with normal ears (N=16) and patients with ventilation tubes (N=114). Tympanometry was performed on each patient prior to audiometric testing. Audiometric test results obtained in normal ears were compared to results for patients with ventilation tubes. For analysis, the ventilation tube patients were separated into two groups, representative of ventilation tube type. RESULTS: Audiometric results obtained using the two transducer types at 250Hz and 500Hz revealed significant differences in threshold for patients with ventilation tubes. Thresholds obtained using insert earphones were generally worse than thresholds obtained using supra-aural headphones for this group. On average, difference in threshold was 14.15dB worse with insert earphones at 250Hz and 9.75dB worse with insert earphones at 500Hz for patients with Sheehy tubes. Average difference in threshold for patients with Donaldson tubes was 13.93dB worse with insert earphones at 250Hz and 8.93dB worse with insert earphones at 500Hz. In addition, thresholds were more variable for patients with ventilation tubes than normal ears at 500Hz. There were no significant differences in threshold for normal ears using both transducers. CONCLUSIONS: When performing pure-tone audiometry, choice of transducer can influence the accurate identification of a low-frequency hearing loss in patients with ventilation tubes. Low-frequency thresholds were generally worse using insert-style earphones to test subjects with tubes, resulting in the apparent identification of a hearing loss. However, with supra-aural headphones, no low-frequency hearing loss existed. There were no significant differences in threshold values using either transducer in normal ears.

Acoustic Impedance Tests↗