Biomedical subjects

Michael G Kendrach

Publications and source records attributed to Michael G Kendrach.

3 recordsLinked to original sources

PubMed2004

Approximate equivalent rosuvastatin doses for temporary statin interchange programs.

OBJECTIVE: To estimate approximate doses of rosuvastatin equivalent to the other hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) for a temporary substitution program. DATA SOURCES: A literature search was conducted to locate clinical trials directly comparing rosuvastatin with other statins that evaluated the magnitude of cholesterol lowering. DATA SYNTHESIS: The mean low-density lipoprotein and total cholesterol values from the clinical trials were assessed. Study results indicate that rosuvastatin is not equivalent to other statins on a milligram-to-milligram basis. CONCLUSIONS: Rosuvastatin appears to be at least 2 and 4 times as potent as atorvastatin and simvastatin, respectively, and at least 8 times as potent as pravastatin and lovastatin.

Cholesterol↗

PubMed2004

Accuracy of abstracts for original research articles in pharmacy journals.

BACKGROUND: Accuracy of abstracts representing original research articles is imperative since these are readily available and biomedical literature readers may not have access to the full-text article. Furthermore, previous reports document discrepancies in published original research abstracts compared with the full-text article. OBJECTIVE: To determine the accuracy of abstracts for original research articles published in nationally represented, widely circulated pharmacy-specific journals (American Journal of Health-System Pharmacy, The Annals of Pharmacotherapy, The Consultant Pharmacist, Hospital Pharmacy, Journal of the American Pharmacists Association, Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy) from June 2001 through May 2002. METHODS: Outcome measures included an omission, defined as data in the abstract not located in the article. In addition, abstracts were considered deficient if these included an omission, inaccurate factual (i.e., qualitative and quantitative) information presented in the abstract that differed from information contained within the text, an inconsistency in following the "Instructions for Authors" for the respective journal, or a discrepancy between the placement of text in the manuscript and a structured abstract. RESULTS: A total of 243 abstracts for original research articles were published in selected journal issues. Evaluation of these abstracts identified 60 (24.7%) abstracts containing omissions; 81 (33.3%) abstracts contained either an omission or inaccuracy. A total of 147 (60.5%) abstracts were classified as deficient. CONCLUSIONS: Results of this analysis demonstrate that improvements are needed within abstracts for original research articles published in pharmacy-specific journals. Authors and peer reviewers should analyze the abstract contents closely to ensure that the abstract accurately represents the full-text article.

Abstracting and Indexing↗

PubMed2003

Bioterrorism web sites for pharmacists.

OBJECTIVE: To identify Internet Web sites for ease of accessibility to bioterrorism-related information, comprehensive provision of bioterrorism-related information, and provision of bioterrorism information that specifically pertains to the pharmacy profession. DATA SOURCES: Web sites of national pharmacy organizations, US government agencies, and medical organizations, as well as Web sites related to bioterrorism. DATA SYNTHESIS: Pharmacists need access to relevant bioterrorism information in a timely manner. An evaluation of Web sites was performed to identify those that include a discussion of the potential infectious microorganisms and prevention and treatment methods, as well as unique features for pharmacy practice. RESULTS: The American Society of Health-System Pharmacists and American Pharmaceutical Association Web sites provide pharmacy-specific recommendations. The Centers for Disease Control and Prevention provides biological agent information and health department contact numbers. Additional agent-specific data are provided by the American Medical Association, The Johns Hopkins University, and the Food and Drug Administration (FDA) Web sites. Information addressing food safety is provided by the FDA. CONCLUSIONS: Pharmacy-specific bioterrorism information is available only at selected national pharmacy organization Internet Web sites. However, other Web sites provide comprehensive bioterrorism information useful for pharmacists.

Bioterrorism↗