Cimetidine in gastric ulcer: a note of caution.
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Biomedical subjects
Publications and source records attributed to N Ananthakrishnan.
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Most adult hernias have a defect in the posterior wall of the inguinal canal even though the initial defect, in an indirect hernia, is the presence of a sac at the internal ring. It is imperative to strengthen the posterior wall without disturbing the normal shutter mechanism of the inguinal canal. A technique is described which achieves this by applying the keel principle to the repair. Data regarding 215 such repairs done during the last five years is presented. The follow-up available however does not satisfy the standard critical criteria and as such this is presented only as a preliminary report and a rational idea.
A series of 17 cases of parotid fistulas seen at one hospital over a 10-year period is presented with detailed analysis of aetiological factors, clinical presentation and therapy. Distinctions between glandular and ductal fistulas have been enumerated and the poorer prognosis of the ductal fistulas, especially of the proximal part, is emphasized. Two-thirds of the fistulas were iatrogenic. Malignancy and oral leucoplakia were unusual causes. Direct duct suture is rarely successful. Ablative surgery carries a significant risk of facial nerve injury. A wide choice of treatment exists for glandular and distal duct fistulas, while for the proximal duct injuries excision is usually necessary. A new alternative operation of vein grafting for such cases is described. Successful closure is obtained in only 50 per cent of patients with long standing fistulas with any method of treatment.
Mastectomy is the commonest operative procedure in the pectoral region. Other procedures include raising of deltopectoral or pectoralis major myocutaneous flaps. Proper postoperative positioning allowing the least tension on the wound and a primary closure without a skin graft is desirable. An attempt was made to mathematically quantify the effect of various arm positions on skin tensions over the axilla, the chest wall and the cervico-thoracic region. It was found that the position of 90 degrees flexion at the shoulder with 90 degrees flexion of the elbow with the hand pointing across or cephalically, on alternate days, was the most suitable. This position does not compromise movements at the shoulder.
Large, advanced, fungating breast tumours are a special problem in developing countries. The surgical treatment is often confined to rescue and relief and primary closure of the excisional defect is highly desirable. Split-skin grafts are often unsatisfactory for many reasons. Full thickness local flaps, cut as thickly as possible, give the best results and the "sheet anchor" in skin cover is the medially based deltopectoral flap. Myocutaneous flaps can be useful in treating low inner quadrant growths and lesions which leave no room for a deltopectoral flap.
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A review of the literature has revealed only 24 cases of retroperitoneal non-functional paraganglioma recorded up to the present date. This report presents three additional cases, in two of which metastasis had occurred at the time of surgery. The clinical presentation and the biological behaviour of these tumours are reviewed in detail, as also are recommendations regarding therapy.
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A case of giant ureteric calculus 12 cm in length is reported. Only 11 cases of such calculi measuring 12 cm or more have been previously reported in the literature. The relevant features of giant ureteric calculus are discussed.
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