Biomedical subjects
Publications and source records attributed to N E Lebedeva.
Studies have been made on peculiarities of defensive reaction in Phoxinus phoxinus to external metabolites produced by the pike Esox lucius and excreted into the basin. It was shown that the skin and mucose of the pike contain low molecular weight substances (m. w. about 1300) which being introduced into the basin serve as a chemical signal of danger to Phoxinus phoxinus.
Protein spectra of the hypophyses of fishes from various taxonomic groups obtained by disc electrophoresis in polyacrylamide gel exhibit high species specificity. By means of biological testing on the loach Misgurnus fossilis, zones of gonadotropic activity were obtained which differ in various species by the electrophoretic mobility. The mammalian gonadotropins obtained reveal lower electrophoretic mobility. The gonadotropins investigated significantly differ in their biological effect.
Polyacrylamide gel electrophoresis reveals differences in the isoenzymic spectra of non-specific esterases from various tissues of H. molitrix. Hypophyseal injections result in changes of the isoenzymic spectra of all the tissues studied. The pattern of changes depends on the tissue examined. Some of the isoenzymes are resistant to hypophyseal injections, whereas the other ones undergo changes which depend on the dose of the hormone.