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Biomedical subjects

N I Bubnova

Publications and source records attributed to N I Bubnova.

34 records · Page 2Linked to original sources
PubMed1978

[Hyaline membrane disease (idiopathic respiratory distress syndrome of newborn infants)].

A review of literature on the morphology and pathogenesis of the disease of hyaline membranes (DHM) in children is presented. The role of predisposing factors in the development of the disease such as inheritance, perinatal asphyxia, prematurity of newborns, diabetes in the mother, Cesarian section, is analyzed. The results of electron microscopic, immunohistochemical and dynamic histological examinations of the lungs in DHM are presented. The current concepts on the association of this disease with a defficiency of a surfactant, alpha1-antitrypsin, hypoperfusion and reduction of fibrinolytic activity of the lung tissue, and with the condition of the vegetative nervous system are discussed.

Cesarean Section↗
PubMedDate not supplied

[The antioxidative defense system in the liver of rat fetuses upon antenatal exposure to lead].

The activity of Zn, Cu-containing superoxide dismutase was studied in the liver of 20-day old fetuses of female rats exposed to different concentrations of lead in different periods and during pregnancy. There were significant changes in the enzyme activity depended on a used dose of lead and on the duration of exposure to this compound. Activation of free radical processes and impairment of the antioxidative defense system are likely to be one of the basic mechanisms responsible for hepatic damage during prolonged antenatal lead intoxication.

Animals↗
PubMedDate not supplied

[Morphological changes in the primordia of the deciduous teeth during an exacerbated course of the antenatal period].

Histologic examination of 380 rudimentary deciduous teeth of 91 stillborn babies or corpses of newborns dead within 16 days after birth and comparison of the results with clinical data brought the authors to a conclusion that the diagnosis of enamel hypoplasia is erroneous because all dental tissues are involved during this condition. Pathohistologic changes in the enamel, dentin, and tissues adjacent to dental rudiment are described in detail, all these tissues developing under unfavorable conditions of antenatal odontogenesis.

Amelogenesis↗
PubMedDate not supplied

[The importance of the cytological study of the tracheobronchial aspirate in newborn infants with the respiratory distress syndrome who are on artificial pulmonary ventilation].

Cytological and pH-metrical investigations of the tracheobronchial aspirate were performed in 43 children with a respiratory distress syndrome (RDS) on artificial pulmonary ventilation. The content over 40% in the cytogram of polymorphonuclear leukocytes (PNL) indicated infectious genesis and below 10%--noninfectious genesis of RDS. The content of PNL in the range of 11-39% requires additional clinical data which would help to establish RDS cause.

Bronchoalveolar Lavage↗