Influence of the abdominal vagi and gastric antrum on humoral control of gastric acid secretion.
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Biomedical subjects
Publications and source records attributed to N Komi.
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Yotsuyanagi's theory is often quoted in the discussion of the etiology of congenital dilatation of the biliary duct (CDBD), but there has been no established etiology as yet. With particular reference to the relationship between anomalous arrangement of the pancreaticobiliary ducts and CDBD, Babbit collected 19 cases of CDBD. The authors also observed the anomalous arrangement in 10 of 24 cases of CDBD (42 percent). Analysis of 570 CDBD cases collected in Japan disclosed that the anomalous arrangement was present in 183 of them (33 percent), dilation of the intraheptic bile ducts in 236 (42 percent), and narrowing and malformation of the bile duct in the hepatic hilum in 58 (10 percent). The authors have proposed a new classification, including these morphologic anomalies of the whole pancreaticobiliary ductal system. This classification provides useful indices in selecting the surgical procedures. The effect of the anomalous arrangement was pathophysiologically studied on dogs. The static internal pressure of the dog pancreatic duct was 14.6 + or - 5.5 cm H2O, and that of the dog bile duct, 8.9 + or - 3.4 cm H2O. Puppies were then operated on by shunting the pancreaticobiliary ducts. As the result, the biliary tract was devastated by pancreatic juice, giving rise to similar pathologic changes to those clinically observed.
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For the long term observation of the electrical activity of the canine alimentary tract, a bipolar silver electrode was devised in our laboratory. The electrode has been demonstrated to be satisfactory in sensing the electrical activity of the alimentary tract. The electromyogram of the esophagus was consisted of very fast spike burst lasting for about 3 to 5 seconds in swallowing actions. The stomach showed a cyclically recurring basic electrical rhythm (BER), which was propagated caudally, and spike burst which was related to the contractile activity of the gastric smooth muscle. The duodenum and small bowel also showed both BER and spike burst in their electrical activity. Thus the electromyograms obtained by our electrode have shown their similarity to those by monopolar electrodes. Furthermore, our electrode has proved its durability, functioning for more than 5 months. Details of the construction of our electrode were described.
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