PubMed Health⌕ Search

Biomedical subjects

N Léger

Publications and source records attributed to N Léger.

52 records · Page 3Linked to original sources
PubMedDate not supplied

Isoenzyme characterization of Leishmania from man, dog and sandflies in the Maltese islands.

As a part of a general survey on leishmaniases and sandflies of the Maltese islands, 22 Leishmania stocks were isolated from human visceral (1) and cutaneous (1) cases, dogs (16) and sandflies (4). They were characterized by the analysis of 15 enzymes. The commonest Mediterranean L. infantum zymodeme, MON 1, was found to cause human and canine visceral leishmaniasis; L. infantum MON 78, which has so far been isolated only in Malta, was the agent of human cutaneous leishmaniasis. Both zymodemes were isolated from the same sandfly species, Phlebotomus perniciosus.

Animals↗
PubMedDate not supplied

Numerical taxonomy of Old World Phlebotominae (Diptera: Psychodidae). 1. Considerations of morphological characters in the genus Phlebotomus Rondani & Berté 1840.

Numerical analyses (correspondence analysis, ascending hierarchical classification, cladistic approach) were applied to the morphological characters of the adults of the genus Phlebotomus Rondani & Berté 1840. They confirm the reliability of the classic classifications, and also redefine the taxonomic and phylogenetic position of certain taxa. Thus, Spelaeophlebotomus Theodor 1948. Idiophlebotomus Quate & Fairchild 1961 and Australophlebotomus Theodor 1948 deserve generic rank. Among the vectors of leishmaniasis, the subgenus Phlebotomus Rondani & Berté 1840 is probably ancient. The results attribute an intermediate taxonomic and phylogenetic position to the taxa Euphlebotomus Theodor 1948 and Anaphlebotomus Theodor 1948, and reveal the probable artificial nature of the latter. The comparatively large numbers of species of subgenera Paraphlebotomus Theodor 1948, Synphlebotomus Theodor 1948 and, above all, Larroussius Nitzulescu 1931 and Adlerius Nitzulescu 1931, suggest that they are relatively recent. The development of adult morphological characters, the validity of their use in taxonomy and proposals for further studies are discussed.

Animals↗
PubMedDate not supplied

Numerical taxonomy of Old World Phlebotominae (Diptera: Psychodidae). 2. Restatement of classification upon subgeneric morphological characters.

Numerical analyses (correspondence analysis, ascending hierarchical classification, and cladistics) were done with morphological characters of adult phlebotomine sand flies. The resulting classification largely confirms that of classical taxonomy for supra-specific groups from the Old World, though the positions of some groups are adjusted. The taxa Spelaeophlebotomus Theodor 1948, Idiophlebotomus Quate & Fairchild 1961, Australophlebotomus Theodor 1948 and Chinius Leng 1987 are notably distinct from other Old World groups, particularly from the genus Phlebotomus Rondani & Berté 1840. Spelaeomyia Theodor 1948 and, in particular, Parvidens Theodor & Mesghali 1964 are clearly separate from Sergentomyia França & Parrot 1920.

Animals↗
PubMedDate not supplied

[French Guiana and bilharziasis].

The authors discuss about the lack of bilharziasis in French Guyana and report the experimental infestation of Biomphalaria glabrata coming from Cayenne with a porto-rican strain of Schistosoma mansoni.

Biomphalaria↗
PubMedDate not supplied

[Efficacy of schistosomicide derivatives, appreciation with electronic microscopy experimental model (author's transl)].

The activity of some schistosomicidal drugs have been studied by electron microscopy on the tegument of Schistosoma mansoni. Results are different and depend of the compound which is tested. Two new compounds: RO 11 3128 and RO 13 3978 are specially active and act in different ways on the tegument. On of them, a benzodiazepine, have been tested in association with an "antibenzodiazepine" compound in order to avoid the sedative action without decrease of the schistosomicidal activity.

Animals↗