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Biomedical subjects

N Pavlov

Publications and source records attributed to N Pavlov.

At least 37 records · Page 2Linked to original sources
PubMed1976

[Pathomorphology of lung alterations in calves naturally infected with the virus of infectious rhinotracheitis].

In addition to diphtheroid rhinitis, and tracheitis, the infectious rhinotracheitis in calves has also been accompanied by a catarrhal-and-necrotic pneumonia. The mucous membrane of the bronchi, bronchioles, and alveoli in such cases is edematous with occasional necrotic areas. The necroses are focal and areactive. The peribronchial lymphoreticular system shows no signs of proliferation. The necrotic lesions in the bronchi and alveoli are considered as the porte d'entrée of the bacterial infection that aggravates the course of the disease and fairly often leads to death.

Animals↗
PubMed1976

[Swine infected with atypical mycobacteria].

Pigs spontaneously affected with tuberculosis responded with well expressed signs to avian tuberculin, and weakly to bovine tuberculin. Mycobacterium avium cultures of serotype--2 were isolated from 76.9% of them, and M. avium cultures of serotype -1-from 23.1% of them. The lymph nodes were enlarged, with granulated cross-section area of presenting multiple necroses, some of the latter being in a process of calcification, and some fully capsulated. Histologic changes were also observed characterized by peritrabecular oedemas, decrease in the lymph elements and proliferation consisting of reticular and epitheloid cells. Although rarely there were also tubercules with giant cells of Langerhans type. Pigs given orally Mycobacterium battey (intracellulare), M. fortuitum, M. aquae, M. vaccae, and M. smegmatis responded with an allergic reaction on the 30th day following infection. The skin reactions were better manifested with the use of avian tuberculin. The blood serum of such pigs contained CFT-positive antibodies that were specific for the Mycobacterium genus. The histopathologic changes in the lymph nodes were of proliferative and infiltrative character. Tubercules of giant cells and necroses with calcification were not established.

Animals↗
PubMed1976

[Experimental Q-rickettsiosis in lambs].

The clinical course, serologic response, and morphologic changes were followed up in month-old lambs infected nasally and via the trachea with Rickettsia burneti at the rate of 10,000 ID50/cm3. Rickettsiae were found in the parenchymal organs, the blood clot, the nasal cavity, the trachea, and the feces of the animals killed on the 7th and 21st day of infection. Complement-fixing antibodies were established in the infected lambs with the use of the complement-fixation test from the 5-6th up to the 160th day (period of testing), the highest value of the titer (1:160) being observed on the 32nd day. Demonstrated were changes in the vessels, and degeneration was found in the liver, kidneys, and other viscera along with proliferative changes in the spleen. Guinea pigs and albino mice were successfully made use of to isolate Rickettsia burneti from the infected parenchymal organs, feces, and others of affected lambs.

Animals↗
PubMed1976

[Pathohistological changes in guinea pigs experimentally infected with Yersinia enterocolitica serotype 9].

A total of forty-five guinea pigs were injected subcutaneously with 0.1 cu cm carboneum tetracholoratum each and were infected with Yersinia enterocolitica serotype 9. Part of the animals (31) were treated at the 24th hour following infection with omnopon (a morphine preparation). All infected guinea pigs developed an infectious process manifested by dystrophic and inflammatory changes in the liver, intestine, spleen, lymph nodes and lungs. Those treated with omnopon manifested a more acute infectious process. After the 13--20th day of infection the lesions became more weakly expressed. On the 50th day the inflammatory reaction was observed in the lymph nodes and spleen only. The mortality rate in both groups was about 50 per cent.

Animals↗
PubMed1976

[Studies of the etiology of cystopyelitis in hybrid swine].

Studies were carried out on the etiology, clinical picture, morphologic changes, and methods of prophylaxis of the cystopyelitis in hybrid pigs. It was established that in the cases studied the etiologic part is most probably played by Escherichia coli having pronounced virulence for albino mice. Clinically the disease was manifested with hematuria--the cardinal diagnostic symptom; histologically there were nephritis, pyelonephritis, and strong edemas on the wall of the bladder. When hematuria appeared the affected pigs died (at the rate of 100 per cent) as a result of acute anemia. Prophylactic measures have been especially successful with the use of streptomycin to which the isolated coli strains proved sensitive.

Animals↗
PubMed1976

[Study of one enzootic of viral diarrhea in calves].

Described is the course of a virus diarrhea in calves aged from 40 up to 180 days, the morbidity rate reaching 50 per cent and the mortality rate--28 per cent. The morphologic survey established erosions and inflammatory lesions in the mouth, abomasum, rumen, and intestines. Histologically, there was balooning degeneration of the cells involved as well as karyopycnosis. Virus strains were isolated from the spleen of diseased calves. They were identified as the causative agent of the virus diarrhea-mucosal disease complex. It was found through immunodiffusion that a specific viral antigen exists in the involved mucous membranes of the intestinal tract. The live vaccine was found to be promising of the immunoprophylactic means tested.

Animals↗
PubMed1975

[Study of cows experimentally infected with atypical mycobacteria].

Cows were infected subcutaneously with Mycobacterium aquae, Mycobacterium fortuitum, Micobacterium vaccae, and Mycobacterium smegmatis. The investigations carried out on the thirtieth day following infection revealed allergic reaction in all cows with close variations when avian and bovine tuberculin were used. The complement-fixation test with blood sera pointed to the presence of specific antibodies for the Mycobacterium genus. The histopathologic reaction in the lymph nodes, established after the slaughter of the animals on the 45th day of infection, was a proliferative-infiltrative one, the epitheloid cells being located at the periphery of the trabecules. Giant cells and necroses were missing.

Animals↗