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Biomedical subjects

N R Farnsworth

Publications and source records attributed to N R Farnsworth.

At least 109 records · Page 6Linked to original sources
PubMed1981

Biological and phytochemical investigation of plants XVI: Strumpfia maritima (Rubiaceae).

An aqueous extract of the flowering tops of Strumpfia maritima exhibited antifertility activity in female rats. The extract also contained the flavonol glycoside narcissin. This article represents the first reported isolation of this flavonoid from the Rubiaceae, as well as the first reported phytochemical and pharmacological investigation of the genus Strumpfia.

Animals↗
PubMed1981

An approach utilizing information from traditional medicine to identify tumor-inhibiting plants.

The search for effective tumor inhibitors for human use from higher plants requires a well-organized, cost and time efficient system for the initial evaluation of plants for potential antitumor activity. Three fundamental approaches currently being employed for the selection of the 750 000 candidate species are discussed. These include random selection screening, the use of information from traditional medicine to gain an insight from existing indigenous preparations, and a review of published experimental data that indicate antitumor activity for extracts of plants. In addition, a fourth approach, involving a combination of the aforementioned methods is proposed. This approach is modeled after a program initiated by the World Health Organization for the purpose of screening and investigating indigenous plants for fertility regulation.

Animals↗
PubMed1980

What is odoratin?

Explore the source record for details and available documents.

Lactones↗
PubMed1980

The development of pharmacological and chemical research for application to traditional medicine in developing countries.

The resolution of the 31st WHO Assembly requests: (1) a complete inventory of medicinal plants, (2) evaluation of efficacy and safety of the plants, (3) standardization of the plants. This involves a great effort, not only from developing but also from industrialized countries, being a task which will take many years and the full-time dedication of many researchers. Any research on the use of plants in traditional medicine should be developed in the framework of the activity of WHO. An example of this type of collaboration is the organization of research on fertility regulating plants in which six universities in different regions of th world are interested. This work must be done in such a way that industry should play a role, because of its greater knowledge of modern technologies, which may lead to a better utilization of plants and their extracts, and its funding and marketing abilities.

Animals↗
PubMed1979

South American plants II: taspine isolation and anti-inflammatory activity.

Croton lechleri L. (Euphorbiaceae), a plant from the Upper Amazon Valley of Peru, yielded the alkaloid taspine. The anti-inflammatory activity of taspine hydrochloride was studied using the carrageenan-induced pedal edema method, the cotton pellet-induced granuloma method, and the adjuvant polyarthritis model.

Alkaloids↗
PubMed1977

Flavonoid constituents from Eupatorium altissimum L. (Compositae).

An aqueous ethanol extract of Eupatorium altissimum L. (Compositae) showed confirmed activity in the P-388 lymphocytic leukemia assay in mice, and the chloroform solubles showed both cytotoxic activity in the 9KB carcinoma of the nasopharynx cell culture assay and antitumor activity in the P-388 lymphocytic leukemia assay. Two flavones, eupatorin and 5-hydroxy-3',4',6,7-tetramethoxyflavone, were isolated and identified. Both were devoid of cytotoxic and antitumor activity.

Animals↗