Inclusion body myositis in a patient with a presumed diagnosis of post-polio syndrome.
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Diagnosis, Differential↗
Biomedical subjects
N Taskos
Publications and source records attributed to N Taskos.
Abducent nerve palsy following transverse fracture of the middle cranial fossa.
Transverse sphenoidal fractures may be associated with a variety of skull base injuries and neural deficits. Among those nerve injuries, oculomotor palsies and particularly sixth cranial nerve palsy, are quite common. Blows on the side of the head in the squamous temporal region may run across the floor of the middle cranial fossa through the greater wing of the sphenoid in the transverse cranial axis. We report three cases of patients who had sustained craniofacial injury which included a transverse fracture of the middle cranial fossa through the sphenoid sinus, extending to the petrous apex and producing abducent, facial, and eighth nerve dysfunction. Spontaneous recovery from diplopia occurred in all cases within 4 months. The management of the patients and the patterns of transverse cranial base fractures and their associated clinical features are discussed.
Abducens Nerve Injury↗
Familial nemaline myopathy: case reports.
Two siblings of two generations in the same family with nemaline myopathy are described. The disease affects all skeletal muscles, especially the facial muscles, producing a typical facial appearance. The diagnosis was made by light microscopy of histologically stained sections of muscle biopsy. The disease in our patients seems to be transmitted in an autosomal dominant manner. The purpose of this article is to emphasize the importance of recognition of the facial appearance by maxillofacial surgeons and the appropriate referral of patients for further neurologic examination.
Adult↗
Regional spinal cord blood flow measurements (r.S.C.B.F.) in spinal cord acute compression caused by an epidural balloon.
Our study was carried out in 34 rabbits which were divided into three groups (A, B, C). In group A (10 animals), a mid-laminectomy of the first lumbar (L1) vertebra was performed and the circulation in the exposed spinal cord segment was examined using both procedures, the videomicroscopy as well as the r.S.C.B.F. measurement (by intraarterial-5th radicular injection of 2.5 mic133 Xe). In group B (10 rabbits) after the performance of L1 vertebra mid-laminectomy, a teflon catheter was introduced through T11-T12 (thoracic) intervertebral foramina and 0.5 ml of metrizamide sodium was injected through the balloon producing, thus, a 36 +/- 1% stenosis in the diameter of the corresponding spinal canal level. Using the procedures described above as well as light microscopy it was shown that, during the period of the 4 hours the experiment lasted, the circulatory disturbances of spinal cord were still reversible. On the contrary, in group C (14 rabbits) where 0.8 ml of metriz amide sodium was injected through the balloon catheter producing, thus, a 52 +/- 1% stenosis in the corresponding spinal canal level, the spinal cord disturbances proved irreversible after the 4-hour period of the experiment's duration.
Acute Disease↗
Improvement of cerebral circulation by extracorporal collateral between the femoral and the external carotid artery in experimentally induced ischaemia.
The purpose of this study was to examine the effect of extracorporal collateral circulation (ECCC) between the femoral and the external artery (ECA) on the cerebral circulation, in experimentally induced ischaemia, in rabbits. The animals were divided in four groups. Seven animals (Group A) were used to determine the injection pressure (150-160 mmHg) at the ECA, necessary to achieve collateral circulation between ECA and internal carotid artery (ICA), after occlusion of ICA. Group B (8 rabbits) was the control group for establishing cerebral ischaemia (CI) by a) ligating the common carotid artery bilaterally, b) coagulating the right vertebral artery and c) exsanguinating the animal (removing 28-30 ml of blood). The induced ischaemia was studied by BP and PCO2 monitoring, CBF measurement, videomicroscopy of surface cerebral vessels, and finally macroscopic and microscopic examination of brain sections. In group C (8 animals)-moderate degree of CI-brain circulation improved in all animals after the application of the ECCC, installed at 135 min after the onset of CI. In 10 animals (group D) with severe and prolonged (225 min) CI, ECCC enhanced the brain circulation in eight animals to a variable degree.
Animals↗
CT findings in temporal arteritis. A report of two cases.
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Aged↗
Focal experimental epilepsy in rabbits.
The present study aimed at producing a chronic model of focal epilepsy in rabbits. In group A (30 rabbits) 0.05 ml alumina gel was injected in the right sensorimotor cortex, while in group B (10 rabbits) normal saline was injected in the same region. The observation period lasted 70 days. All group A animals developed spontaneous focal or focal initiated seizures that continued throughout the study. The rate of seizures varied in different animals. Both interictal and ictal epileptiform activities were recorded in the ECoGs. Histological examination showed a typical alumina granuloma with gliotic reaction adjacent to the granuloma.
Aluminum Hydroxide↗