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Biomedical subjects

N V Beliaeva

Publications and source records attributed to N V Beliaeva.

At least 19 recordsLinked to original sources
PubMed1991

[Simultaneous flow cytometric analysis of cell cycle and subpopulations of immunocompetent cells in workers participating in the clean up of the Chernobyl Atomic Energy Station accident].

Surface phenotype and cellular cycle of nonstimulated peripheric blood mononuclear cells of 35 cleaner-worker with dose commitment 0.05-0.25 Gy and 12 control persons were studied by means of flow cytometry. Differences in cellular cycle were found, they needed further investigations. The details of the method promoting its reproducibility are described.

Accidents↗
PubMed1991

[Immunological aspects of the study of contingents of population exposed to ionizing radiation effects as the consequence of the Chernobyl AES accident].

The immune system was examined in those who participated in the liquidation of accident sequelae at the Chernobyl Atomic Power Station and the population exposed to ionizing radiation. Alteration in surface antigenic markers of basic regulatory subpopulations of immunocompetent cells and metabolic changes are caused by radiation and co-existent somatic diseases. Typing for HLA antigens and proteins with a genetically determined phenotype revealed characteristic features of their distribution for the general population.

Accidents↗
PubMed1990

[Morphometric analysis of immunocompetent cells].

The authors have developed the technique of morphometric analysis of human peripheral blood immunocompetent cells by means of Laborscal PSA-1, PSL-1 conductometric cytoanalyzer and DBK-010 computer-processing of the resultant histograms. The method was tried in examinations of more than 400 patients with various diseases and in studies of lymphocyte activation changes. Formulae for calculation of cellular diameters and volumes are offered, as is the program for histogram processing.

Cytological Techniques↗
PubMed1990

[The immunological monitoring of patients with acute radiation sickness 12 to 36 months after the accident at the Chernobyl Atomic Electric Power Station].

Immunoassays of the 1st and 2nd levels were investigated in patients with acute radiation disease 12-36 mos. after irradiation. A decrease in the level of helper/inducer T-lymphocytes, a tendency to a decrease in the number of suppressors and an increase in the number of theophylline-stimulated T-cells in patients with acute radiation disease of the 3rd degree were observed. Control of the immune status of this group of patients is recommended.

Accidents↗
PubMed1986

[Experience in isolating Campylobacter jejuni from patients with acute intestinal diseases].

Erythrite agar, a commercial culture medium produced by the Research Institute for Culture Media (Makhachkala, USSR), is suitable for the cultivation of C. jejuni after the addition of hemolized sheep blood. The addition of antibiotics to the medium permits its use for the isolation of C. jejuni from feces. By means of this medium C. jejuni has been isolated from the feces of 10% of patients hospitalized on account of acute infectious intestinal diseases.

Acute Disease↗
PubMedDate not supplied

[Expression of the membrane antigens in native and cryopreserved embryonic precursor cells].

Native and cryoconservated human embryonic liver cells at different stages of gestation (5, 6 and 7 weeks) have been studied. Tissue desagregation was performed by trypsinisation technique. A part of the samples was studied after their trypsinisation, another part - after 3-week storage. Cell viability of all samples was higher than 90%. CD34 antigen expression was highest in 5-week gestation samples. The tendency of the deacrease of CD34 antigen expression was seen in 7-week gestation samples. CD34 antigen expression was higher in the samples after their cryoconservation than in native ones. The CD34 antigen expression afer their cryoconservation was accompanied by an increase in numbers of cells expressing CD38, CD45RA, CD33, CD13 and CD14 antigens as well as markers of erythroid precursor cells -CD71, CD36 and CD45RO. Percentage of alpha-actin positive cells was higher in 6- and 7-week samples. An increase in alpha-actin positive cell fraction has been seen also in samples after their cryogenic conservation.

Antigens, CD↗