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Biomedical subjects

N Z Slinchenko

Publications and source records attributed to N Z Slinchenko.

At least 19 recordsLinked to original sources

[The role of cytological studies in the clinical management of dust-induced occupational diseases].

Mineral dusts induced immunopathies in silicosis patients can be traced through changes in the composition, quantity and activity of the mononuclear phagocytic system detected in broncho-pulmonary secretions. It was established that the development of chronic non-specific pulmonary diseases and dust bronchites were caused by local immunopathies. A cytologic test for pulmonary and bronchial local protection was proposed through determining the degrees of pathologic developments, gravity of bronchitis, its predominant syndromes, and surveillance of the therapeutic course.

Dust↗

[The morphological determination of immune reactivity in coniotuberculosis].

A study was performed on the immune reactivity of coniotuberculosis cases among iron-ore miners from initial to developed stages by means of a postmortem morphometric analysis of the pathologic changes. It was revealed that the disease was characterized by a marked decrease in immune reactivity which progressed along with the disease. It was established that the process was influenced by the age, the ferrum oxide (III) and cremnium dioxide content in the lungs, and the TB infection as such. Much influence was also caused by other sporadic environmental factors.

Adult↗

[Diagnostic errors in silicotuberculosis (clinical-autopsy comparisons)].

Basing on 42 post-mortem examinations of silicotuberculosis cases, the contributors display the most frequently encountered errors in diagnosing this disease. Silicotuberculous bronchadenitis, conglomerate-cirrhotic lower-lobe silicotuberculosis and their complications (e.g. concomitant pericarditis and endobronchitis) are the most difficult cases for detection. To avoid diagnostic errors, a most detailed case history study is needed, along with a complex clinico-functional and tomography examinations, a wide use of endoscopy and bacteriological techniques.

Autopsy↗

[Bronchoscopic diagnosis of pulmonary tuberculosis in miners].

Two hundred and thirty nine records of bronchoscopic examination of miners from iron ore mines, including 114 patients with active pulmonary tuberculosis were studied and the frequency of specific and nonspecific endobronchitis and functional, anatomical and hemocirculatory disorders was determined. Qualitative estimation of the endoscopic symptoms and computer-assisted analysis enabled one to validate the direct and probabilistic bronchoscopically evident signs of active tuberculosis. The data on the mature, frequency and diagnostic value of some endoscopic signs should be considered in differentiation of tuberculosis in miners (without pneumoconiosis).

Adult↗

[Risk factors for the development of siderosilicotubeculosis].

The main risk factors on siderosilicotuberculosis developing in conditions of modern ore mining industry are high tuberculosis infestation of miners and patients with siderosilicosis, presence of residual changes in the lungs of pneumoconiosis and unspecific character. Siderosilicotuberculosis is diagnosed, as a rule, in miners and patients with siderosilicosis at the age of 45 years with 15 year length of work in the mine.

Adult↗