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Biomedical subjects

N Z Slinchenko

Publications and source records attributed to N Z Slinchenko.

21 records · Page 2Linked to original sources

[Some aspects of morphological manifestations of chronic gastritis in miners].

Morphology was studied together with the condition of the local cell-bound immunity in 24 patients who were not exposed to occupational hazards in their occupations and in 32 miners with a long length of service. The above subjects underwent esophagogastroduodenoscopy involving taking of gastrobiopsy specimens. In miners there prevailed chronic atrophic gastritis. Immune mechanisms are involved in its pathogenesis, which fact is evidenced by the lymphoid-and-plasmocellular infiltration of the mucous membrane with a plentiful concentration of plasmatic cells and formation of lymphoid folliculi. They run their course against the background of an apparent lowering of local cellular defence, which event determines progression of chronic atrophic gastritis.

Cell Count↗

[The diagnosis of chronic dust-induced bronchitis].

In dust-induced bronchitis, alterations in the pulmonary parenchyma present themselves in the main cellular indices for bronchioalveolar lavage (BAL), thought to be of much importance to its diagnosis. A total of 53 patients with initial and manifest forms of dust bronchitis underwent BAL. There has been found the following: a decrease in the mononuclear phagocyte system cells (MPhS) reflecting the state of local cellular immunity; rise in the amounts of coniophages, suggesting phagocytic activity of alveolar macrophages (AM) and dust blockade of MPhS cells; emergence and augmentation of counts of gigantic Pirogov-Langhans' cells characteristic of tuberculous granulomas, and also decrease in the counts of lymphocytes. There is a striking decrement in the vitality of AM, with polycytosis being commonly seen. Detection of granular forms of Mycobacterium tuberculosis in BAL and Pirogov-Langhans' cells enables a major proportion of "dust-induced bronchitis" to be considered as belonging to the silicotuberculous process.

Bronchitis↗