An analysis is presented of the nature, number and relative molecular mass of the polypeptides of three influenza virus strains-A/Romania 1/73 (H3N2), A/Romania 1/75 (H3N2), and B/Romania 34/74-isolated during different epidemic outbreaks. The results obtained indicate some similarities between the protein subunits of the two influenza A virus strains (as concerns virus surface and nucleocapsid components) and point out the particular properties of the influenza B strain.

Orthomyxoviridae↗

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Estimation of avidin activity by two methods.

The biological activity of avidin was estimated by two different methods. The spectrophotometric method used the avidin titration with biotin in the presence of 4 hydroxiazobenzen-2'carboxilic acid as indicator. In the radioisotopic determination the titration with tritiated biotin was accomplished. Both methods led to the same results, but the spectrophotometric one is less avidin expensive and more rapid, being more convenient.

Animals↗

PubMedDate not supplied

The control of some viral epidemics by antiepidemic programmes elaborated by an expert system.

A base of data for viral epidemiological studies is presented containing correlation between outer symptoms (observable characteristics of the mass morbid phenomena), inner symptoms (characteristics of intensity of elementary processes implied in the virosis propagation) and influencing factors (risk or protective ones). A resolutive nucleus of processing these is divided in to three parts: an inductive one (specification of the mentioned correlations, of the mathematical model and its equation solutions); a deductive one (explaining or prognosing the epidemiological evolution); a decisional one (specifying the antiepidemic services, necessary for a possible or desired reduction of the morbidity).

Disease Outbreaks↗

PubMedDate not supplied

[Biotin-T-(G). Its synthesis and use in virology].

Explore the source record for details and available documents.

Avidin↗

PubMedDate not supplied

[35 years of research and study in radiovirology at the Stefan S. Nicolau Institute of Virology].

The report presents researches conducted in the field of radiovirology, these 35 last years, at the Radiovirology Central Laboratory of the Academy of Medical Sciences: ionizing radiation little dose effects on the evolution of virus infections, virus migration through the infected organism and its stocks in different organs, intracellular synthesis of viruses, radioisotope characterization of viral nucleic acids, studies of viral molecular biology, radioimmunologic diagnosis of virus diseases, virus inactivation and sterilization through ionizing radiation, space virology studies within "Intercosmos" research program.

Academies and Institutes↗

PubMedDate not supplied

[The potentials for immunization against influenza using liposome-incorporated viral surface antigens].

Studies were conducted using uni- and multilamellar liposomes to establish optimum conditions for influenza antigen incorporation in view of their transport to the target cells for experimental influenza prophylaxis in hybrid white mice. Radiometric determinations showed a good level of preparation purification, a good efficiency of incorporation in liposomes of the active biological material, the liposome linked radioactivity distribution among different organs. Charged liposomes induced solid and long lasting resistance against influenza control infection.

Animals↗