[ADH detection in human blood cells].
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Biomedical subjects
Publications and source records attributed to O Grüner.
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The applicability of the ethanol dilution (ED) technique for total body water (TBW) determination in uremic patients was studied. 73 TBW measurements were performed on 28 patients. As the basic parameters underlying the ED technique showed nearly normal values (Widmark factor r = 0.722 plus or minus 0.0786, normal = 0.710 plus or minus 0.090 g/kg; beta 60 = 0.121 plus or minus 0.037, normal = 0.140 plus or minus 0.018 g/kg x 60 min; "rectilinear' course of the blood ethanol elimination curve), the ED technique for TBW measurements is well applicable to uremic patients. Subclinical hyperhydration was diagnosed (TBW = 57.88 plus or minus 8.08% of body weight, normal = 52.6 plus or minus 5.4%) in 61% of the cases.
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A good correlation between the actual phenotype distribution of esterase D and the expected distribution was found in the analysis of a random sample of 2028 unrelated persons, 54 umbilical cord blood samples, 406 mother/child comparisons, 24 family investigations, one fraternal and 32 identical twin investigations. The assume gene frequencies in Northern Germany were calculated for Es D1 =0.8935 and Es D2 =0.1065 for an aggregate sampling. Gene defects were not observed, and one family exhibited the variant Es D4 in the father (Es D 4--1) and son (Es D 4--2). Likewise, these phenotypes distinctly distinguish themselves by electrofocusing from the phenotypes Es D 1, Es D 2--1, and Es D 2.
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The photographic identification of a skull through the well-known superprojection technique can be modified and decisively improved by the use of a video-tape system. The identification method based on electronic photo composition is methodically simple to use. It offers the examiner the possibility to recognize the relationship between bone and soft part proportions, and the structure of the bone surface and the details of the soft part shape, as a concrete, tangible characteristic of identity to a substantially greater extent. The large number of controllable characteristics inherent in the ihgh degree of individuality of the skull offers not just an either/or "The skull fits"/ "It does not fit" into a photograph, but achieves proof of disproof of identity.
Skull identification by electronic photo-composition can, with the help of a video-animation compositor, be further developed beyond the pure superprojection technique into an animated picture difference image. The employment of this combined technique to be recommended on account of the improved possibilities of control to be realized in the congruity of the superprojection composite picture.
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