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O N Chernysheva

Publications and source records attributed to O N Chernysheva.

23 records · Page 2Linked to original sources

[Status of the lipid phase of plasma membranes of the rat heart after repeated exposure to an alternate magnetic field of 50 Hz frequency].

The concentration of lipids and spectrum of phospholipids in plasma membranes of hearts of rats exposed for 15 times to intermittent (1:2) alternative magnetic field of 50 Hz and 9.4 mT were measured. This exposure lead to accumulation of lipids and increase of free fatty acids, triacylglycerides, cholesterol esters and phospholipids (although to a smaller extent). The cholesterol/phospholipids ratio decreased significantly. The spectrum of phospholipids was similar to that in the controls, except for phosphatidyl inositol whose content grew.

Animals↗

[Effect of an alternating magnetic field of industrial frequency on the lipid composition of the rat liver].

Multiple application (15 runs for 5 hours a day) of an alternative magnetic field of industrial frequency causes changes in lipid spectrum and phospholipid fractional composition of mitochondria and postmitochondrial fraction in rat liver. A decrease in the level of free fatty acids, triglycerides and cholesterol esters in mitochondria is registered, which presumably indicates an increase of the fats use in the cell's energetics. Changes in the phospholipid composition of mitochondria are negligible. In contrast to mitochondria, accumulation of lipids--triglycerides, cholesterol and its esters against a background of disbalance in phospholipid composition is established, which may presumably be one of the reasons for development of destructive infringements in the liver parenchyma during application of the alternating magnetic field.

Animals↗

[Peculiarities of carbohydrate energy and nitrogen metabolism in rat brain affected by magnetic fields of commercial frequency].

Carbohydrate oxidation, the coupling of oxidation with phosphorylation and the level of nucleic acids in the brain tissue were studied as affected by variable magnetic fields of commercial frequency (50 Hz) depending on intensity and regime of generation. A repeated effect (15-seances) of the 32 kA/m continuous magnetic field decreases the content of glycogen, creatine phosphate, intensity of oxygen uptake and etherification of inorganic phosphate, glutamine and increases the DNA content. The 7.5 kA/m continuous magnetic field has no effect on the studied metabolic indices in the brain whereas the interrupted field (1s impulse duration, 2s interimpulse interval) of the same intensity and exposition lowers the amount of glycogen, glucose, creatine phosphate, the RNA and DNA exposition lowers the amount of glycogen, glucose, creatine phosphate, the RNA and DNA levels, activates the oxidation processes, intensifies their coupling with phosphorylation.

Animals↗