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Biomedical subjects

O Staindl

Publications and source records attributed to O Staindl.

46 records · Page 3Linked to original sources

[Head and neck manifestations of lymphogranulomatosis X (author's transl)].

Immunoblastic lymphadenopathy was first described in the german literature in 1975 by Lennert as "Lymphogranulomatosis X." The disease is characterized by generalized lymphadenopathy, hepatosplenomegaly, dysproteinemia, fever and hyperergic reactions such as pruritus, skin rush and eosinophilia. The first ORL occurrence of the disease in Waldeyer's ring and cervical lymph nodes is reported. The histologic picture is characterized by a vascular proliferation with immunoblasts, plasma cells and interstitial amorphous acidophilic material but without Sternberg cells. The origin of the disease from primary malignant neoplasia or hyperergic reactions has not yet been defined. Although prognosis is uncertain and therapy limited, the best management involves small doses of corticoids, supplemented by antibiotics.

Aged↗

[Tissue adhesion using highly-concentrated human fibrinogen on the example of free, autologe skin-grafting (author's transl)].

A report is given about the clinical experiences, made with a biological adhesive-system, consisting in thrombin, native human fibrinogen and clotting factor XIII. We used this adhesive-system in 28 cases of free skin-grafts, without any other kinds of skin-fixation. The highly adhesive properties, the good tissue compatibility recommend this system for using in free skin grafting. Possibilities for use in other kinds of operations in O.R.L. are discussed.

Aged↗

[Saunders-plasty in case of hereditary teleangiectasia using highly-concentrated human fibrinogen for tissue-adhesion (author's transl)].

A report is given about the Saunders-plasty in a case of Morbus Osler. A 66-year-old female patient had been successfully treated with this method after a ligature of the external carotid artery had to be performed due to heavy bleeding from the teleangiectasia of the bilaterally mucous membrane of the nose. To apply the split thickness skin graft a method of tissue-adhesion, using highly-concentrated human fibrinogen was used. Human fibrinogen, thrombin and blood-clotting factor XIII make an effective physiological tissue glue.

Aged↗

[Rhabdomyosarcoma of the skin].

Rhabdomyosarcomas are malignant tumors, and especially occur in childhood. In adults they are extremely rare. A pleomorphe rhabdomyosarcoma of the skin, localized on the nose of an 85-year old female patient, is reported. After surgical removal the defect was reconstructed with a full skin graft. The four histologic types of rhabdomyosarcoma (pleomorphic, alveolair, embryonal, botryoid) are discussed.

Aged↗

[The extreme flat nose, its formation and correction (author's transl)].

The extremely flat nose is a handicap because of nasal airway obstruction, and its consequences, and cosmetic unsightliness. This problem which is rarely discussed in the literature is considered to be inherited. We feel that it is also traumatic in origin. Two patients are presented in whom trauma to the nose is known to have occurred at birth by obstetric forceps. The surgical correction of the flat nose should restore normal function and produce a cosmetically satisfactory result.

Adult↗

Tissue adhesion with highly concentrated human fibrinogen in otolaryngology.

This paper summarizes a tissue adhesive system consisting of highly concentrated human fibrinogen and thrombin. The addition of blood-clotting factor XIII stabilizes the adhesive system against fibrinolysis. Although the adhesion system cannot and should not replace surgical suture, it provides valuable assistance in tissue synthesis and in local hemostasis, particularly in cases where conventional suture methods are especially difficult to apply. In addition to good adhesion, an elastic consistency, and good tissue compatibility, the adhesive is completely absorbed and, therefore, preferable to conventional tissue adhesives based on cyanoacrylate. The system has been used successfully in split thickness skin graft application, myringoplasty, repair of dural defects, hemostasis after tonsillectomy, and achieving an airtight seal in tracheoplasty.

Animals↗

Surgical management of rhinophyma.

The author's methods for the treatment of rhinophyma is described. Nasal lesions are removed in a three-step procedure. The resultant wound surfaces are sealed with fibrin sealant, consisting of highly concentrated human fibrinogen which is clotted with a thrombin solution. The resultant fibrin clot adheres firmly to the wound surface. Spot-bleeding from numerous small vessels is controlled by sealant application. Postoperative wound healing is accelerated and cosmetic results are excellent.

Humans↗