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P Audoly

Publications and source records attributed to P Audoly.

At least 19 recordsLinked to original sources
PubMed1979

Cutaneous T-cell lymphoma in association with a monoclonal gammopathy.

Monoclonal gammopathies and other abnormalities of immunoglobulin production may characterize or frequently be associated with B-cell lymphoproliferative disorders. We describe a patient with a T-cell cutaneous lymphoma, expressed clinically as Sézary's syndrome, in association with an immunoglobulin A type kappa M-component monoclonal gammopathy. No evidence for the coincident presence of a malignant plasma dyscrasia was found. This clinical association may lend clinical support to the concept that Sézary's syndrome is a T-helper-cell malignant proliferation. A colonic carcinoma was also present, possibly representing a second manifestation of a functionally abnormal cellular immune system.

Aged↗
PubMed1978

[Allergic granulomatous angitis. A report on 4 cases (author's transl)].

The authors describe four new cases of allergic granulomatous angiitis presenting symptoms of bronchopneumonia with asthma, weight loss, and persistent fever. There was associated eosinophilia in each case, and the outcome was rapidly fatal. Autopsy confirmed the presence of characteristic lesions; necrotizing angitis, vein involvement, and extra-vascular granulomatous infiltration, mainly in the lungs and heart. The characteristic clinical, biological, and histological changes seen in Churg and Strauss's syndrome should enable differentiation from other granulomatous angititis affections, especially PAN. A different diagnostic approach is needed, however, as surgical biopsy of the lungs, and/or needle biopsy of the liver is necessary.

Adult↗
PubMed1977

[Angio-immunoblastic lymphadenopathy with dysproteinemia. Apropos of 5 cases].

Angio-immunoblastic lymphadenopathies with dysproteinemia represent a new entity characterised clinically by superficial lymphadenopathy splenomegaly more frequent than hepatomegaly, marked general signs and skin manifestations often triggered off by drugs. The laboratory disturbances include immue disorders, polyclonal dysproteinemia, anti-red cell autoimmunity. It is above all the histology which makes this entity original: polymorphic cellular proliferation with immunoblasts, plasmablasts and plasma cell disturbing the normal lymph node architecutre, intense vascular neogenesis and deposits of extra-cellular amorphous substances. This histology corresponds to a non-sarcomatous lymph node hyperplasia, probably due to a deficit in T suppressive function on the production of antibodies.

Aged↗
PubMed1976

Miniature chromatography of haemoglobin A2 and heterozygous beta thalassemia.

172 beta thalassemias are detected by applying a new method of haemoglobin A2 determination: Miniature chromotography on DEAE cellulose. This procedure is simple, fast, accurate and there is no significant difference with macro-chromatography. It is proposed as standard method for determination of hemolgobin A2. This study was made on 400 patients suspected of beta thalassemia, the majority of which presented with a considerable microcythemia.

Adolescent↗