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Biomedical subjects

P Roll

Publications and source records attributed to P Roll.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Dilatation and tortuosity of episcleral vessels in open-angle glaucoma (author's transl)].

We studied two patients with unilateral open-angle glaucoma and bilateral dilatation and tortuosity of the episcleral vessels; the condition was thought to be congenital. Gonioscopy showed that all the eyes were engorged with blood. Episcleral venous pressure was not measured, but resistance to outflow, measured tonographically, showed a marked increase. The clinical significance of this type of glaucoma is pointed out.

Adult↗
PubMed1980

[Dilatation and tortuosity of episcleral vessels in open-angle glaucoma. II. Electron microscopy study of the trabecular meshwork].

The trabeculectomy specimen from a case of unilateral open-angle glaucoma with dilatations and tortuosities of episcleral vessels was investigated electron-microscopically. The cribriform region and the adjacent trabecular lamellae were densified and fused by extracellular depositions and hyalinization of the trabecular lamellae. These alterations permit the conclusion that the glaucoma was caused by increased outflow resistance in the inner wall of Schlemm's canal.

Dilatation, Pathologic↗
PubMed1979

The trabecular meshwork of a non-glaucomatous eye with the exfoliation syndrome. Electronmicroscopic study.

The trabecular meshwork of a non-glaucomatous eye with the exfoliation syndrome was investigated. The exfoliation material was found mainly in massive deposits in the subendothelial region of the outer and inner wall of Schlemm's canal, in the cribriform area and the uveal meshwork. The other alterations of the trabeculum corneosclerale corresponded to the age of the patient. The concept that the accumulation of exfoliation material is an important pathogenetic factor in the development of glaucoma was not confirmed by this study.

Aged↗
PubMed1979

[Retinal detachment surgery: Incidence and causes of silicone sponge implant rejection].

In 51 patients with retinal detachments silicone sponge implants have been applicated. In 9 of these cases (17,6%) the implants had to be removed 3 weeks to 16 months postoperatively because of inflammatory reactions. The influence of these complications on the healing of the retinal detachment is considered as relatively unimportant. In light- and electron-microscopic examinations we could establish that the reactions are mainly caused by infections (which primarily spread within the caves of the sponge implants). Chronic infections caused by so-called apathogenic bacteria are more frequent than acute infections by so-called pathogenic micro-organisms. A foreign body reaction could be proved only in one case, in which the sponge was loosened and displaced. Defence reactions against the foreign body material probably develop only if mechanical irritation of the tissue is caused by the sponge material.

Adult↗
PubMed1979

[Electronmicroscopic studies of the trabecular meshwork in corticosteroid glaucoma].

The tissue specimen of a 41-year-old patient with cortisonglaucoma, obtained by trabeculectomy, was examined by electronmicroscope. There are massive depositions of band-like and linear arranged structures in the cribriform area and adjacent lamellae of the trabeculum corneosclerale. The pathways for aqueous humor of this region are almost completely obstructed by this material. That is the reason for an increased outflow resistance. The cells of this area show signs of degeneration and are reduced in their numbers. -- The cortisonglaucoma differs from all the other forms of glaucoma especially from glaucoma simplex by these characteristic deposits.

Adult↗
PubMed1978

[Light- and electron-microscopic examinations of deep keratomycosis (aspergillosis) (author's transl)].

Light-microscopic and ultrastructural examinations of a corneal button with deep keratomycosis revealed that keratocytes are partly injured and partly of normal structure. In the cellular reaction, macrophages especially, are found that encircle hyphae with pseudopodia or cover the apical end of the fungi. In many sections, the fungal walls are very resistant to phygocytosis, but, on the contrary, the cytoplasm is damaged earlier and more severely. The cellular reaction in the anterior chamber is massive and intensive with predominance of macrophages.

Aged↗
PubMed1978

[The glaucoma in heterochromic cyclitis Fuchs. Gonioscopic studies and electron microscopic investigations of the trabecular meshwork (author's transl)].

Seven patients suffering from heterochromic cyclitis Fuchs had been investigated by gonioscopy after paracentesis of the anterior chamber. Independent to previous intraocular pressure and tonographical results parts or all of the canal of Schlemm were filled with blood, followed by haemorrhage into the trabecular meshwork on several sites and bleeding into the anterior chamber. Three of the patients were operated on because of a chronic secundary glaucoma and the dissected trabecular meshwork was investigated by electron microscopy. Atrophy of the inner--and outer wall of the canal of Schlemm as well as missing of the endothelium of the trabecular meshwork was to be observed. Discussing the gonioscopical observations and electron-microscopical results the glaucoma in heterochromic cyclitis Fuchs seems to be caused by a collapse of the canal of Schlemm and not by increasing resistance in trabecular meshwork by sclerosis or hyaline membranes.

Aged↗
PubMed1977

[Experimentally induced immonological reaction of the eye after keratoplasty. I. Lightmicroscopy (author's transl)].

After sensitization of a rabbit with soluble human cornea proteins a hetero-keratoplasty (man-rabbit) is performed with exactly determined antibody titer. Light-microscopic investigations showed that the epithelium of the transplant is involved in this severe humoral immune-reaction mainly. In the area between receptor's and donor's cornea impressive changes could be observed.

Animals↗
PubMed1977

[Experimentally induced immunological reaction of the eye after keratoplasty. II. Ultrastructural changes of the receptor's cornea (author's transl)].

Ultrastructural changes of the receptor's cornea of a rabbit by experimentally induced immune-reaction were communicated. The finding of plasma-cells proves the generation of humoral antibodies. Granulocytic elements are shown in the transplant or react with diffusing antigen-antibody-complexes already in the stroma of the receptor's cornea.

Animals↗
PubMed1976

[Ultrastructure of macular corneal dystrophy (Groenouw II): investigations of paracentral deep corneal layers (author's transl)].

Electron microscopic studies proved, that in cases of macular corneal dystrophy (Groenouw II) abnormal deposits of acid mucopolysaccharide are demonstrable in the different layers of the cornea in a polymorphic form. Because of the investigations now performed it can be established, that the opacities of the paracentral, deep corneal layers result from both dispersed vesicular and plaque-like deposits of storage material in the border area of the stroma and Descemet's membrane.

Collagen↗
PubMed1976

[Silicon sponge: ultrastructural examinations in chronic infection (author's transl)].

Ultrastructural examinations of a silastic sponge implant (which was removed with the clinical diagnosis rejection against the silicon material) revealed massive infiltration of so called apothogenic bacteria and macrophages. The results of this examination support the idea that in most of the cases with symptoms of inflammation, there is not a rejection against the sponge material itself but acute or chronic bacterial infection. In the bradytrophic area of the sponge socalled apathogenic bacteria may grow and lead to considerable reactions, because antibodies are decreased.

Bacteria↗
PubMed1976

[Ultrastructure of the granulomatous reaction against Descemet's membrane (author's transl)].

Ultrastructural findings in regard to the so-called granulomatous reaction against Descemet's membrane indicate that the membrane is phagocytized in the form of small clumps. Basically epithelial cells and, to a lesser extent giant cells, participate in the phagocytosis. In addition to the connective tissue, the epithelium is fairly actively involved in the regeneration of the cornea.

Adult↗
PubMed1975

[Electron microscopic investigations of vitreous collagen after treating the vitreous with liquefying substances (author's transl)].

By electron microscopic studies collagenase, hyaluronidase, HCl, ascorbic acid, and iron ions have been found to attack the collagen fibers of bovine vitreous. Because of the possible role of ascorbic acid in collagen synthesis and the ability of ascorbic acid to degrade hyaluronic acid and collagen we suggest that the ascorbic acid of the vitreous essentially participates in construction and metabolism of the vitreous body.

Animals↗