PubMed Health⌕ Search

Biomedical subjects

Patricia Price

Publications and source records attributed to Patricia Price.

61 records · Page 4Linked to original sources
PubMedDate not supplied

The molecular and clinical impact of hepatocyte growth factor, its receptor, activators, and inhibitors in wound healing.

Wound healing involves a number of cellular and molecular events, many of which are controlled by soluble growth factors. In the process of healing, hepatocyte growth factor, a cytokine known to act as mitogen, motogen, and morphogen, has been postulated to play multiple roles during several stages of this complex biological process. Produced primarily by stromal fibroblasts, hepatocyte growth factor regulates angiogenesis, vascular permeability, cell migration, matrix deposition and degradation, and other biological processes. The current article discusses recent progress in understanding the multiple roles played by this growth factor in tissue repair.

Hepatocyte Growth Factor↗
PubMedDate not supplied

Living with venous leg ulceration: issues concerning adherence.

Compression therapy is advocated for the treatment of chronic venous leg ulceration and the proportion of patients whose ulcers heal appears to be directly related to adherence (Moffatt, 2004). The aim of this study was to examine patients' understanding of adherence, in terms of their own experiences of compression bandage systems. Following full ethical approval, a purposeful sample of 6 participants was recruited to take part in a focus group. Free-flowing conversation was encouraged so that the participants could discuss issues that were important to them, although a series of prompts were available to stimulate the conversation when necessary. Four major themes were identified using a phenomenological approach: frustration with the healthcare system leading to a feeling of complacency with primary healthcare teams; functional limitations leading to adaptation of everyday life situations (e.g. bathing and coping with pain); emotional reactions affecting well-being and body image, and perception of others; and avoidance of transport, shopping and holidays.

Activities of Daily Living↗
PubMedDate not supplied

Survey comparing clinicians' wound healing knowledge and practice.

A cross-sectional design in the form of a self-administered postal questionnaire was sent to 238 staff of a general hospital to compare wound healing knowledge and practice. Seventy-four questionnaires were returned (response rate = 31.09%). No significant statistical differences were identified between the groups. Wound care practices demonstrated a lack of evidence-based care along with the continued use of outdated and hazardous practices. Knowledge was primarily sourced from colleagues and personal experience, with journals and courses favoured by the specialized clinicians. The clinicians rated pre-graduate training as inadequate. Medical staff dominated decision-making in specialized groups, while the responsibility was shared between the nurse and the tissue viability nurse in non-specialized areas. The clinicians identified clinical effectiveness and availability as influencing their dressing choices.

Attitude of Health Personnel↗
PubMedDate not supplied

Unrestricted access to mental health services.

BACKGROUND: This study examines referrals to a nurse-led, community-based, acute psychiatric assessment and treatment centre in the north west of England which operates an open referral system. Data were collated over 12 months and the total number of assessments was 1,544. It focused on the appropriateness of emergency assessments, which accounted for 29 per cent (n = 446) of the total. In considering 'appropriateness' the authors examined each assessment by source, risk, diagnosis and outcome. CONCLUSION: The results show that professionals and non-health professionals, such as the patient themselves, carers or a voluntary group, are equally likely to make inappropriate referrals, but, overall, open access was used efficiently by both groups. The results also indicate that open access to the service enabled early intervention for high-risk client groups. Implications for professionals and services are discussed.

Community Health Centers↗
PubMedDate not supplied

Evaluating the effectiveness of Tegapore wound-contact material.

During wound healing, new-forming granulation tissue is often extremely fragile and can be easily disrupted during dressing changes. This can lead to a delay in the completion of wound healing and increased pain and discomfort for the patient (European Wound Management Association, 2002; Fear, 2002).

Aged↗
PubMedDate not supplied

Assessing pain at wound dressing-related procedures.

This article is an abstract from a new guide, Principles of Best Practice: Minimising Pain at Wound Dressing-Related Procedures. It is an educational initiative of the World Union of Wound Healing Societies (WUWHS). The guide has been inspired by two seminal documents: the European Wound Management Association's position document, Pain at Wound Dressing Changes (EWMA, 2002), and Practical Treatment of Wound Pain and Trauma: A Patient-centred Approach (Reddy et al, 2003). As an international educational initiative, the WUWHS document is aimed at anyone involved in dressing-related procedures anywhere in the world. This article summarises the section on best practice in the assessment of wound pain.

Bandages↗