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R A Cawson

Publications and source records attributed to R A Cawson.

At least 19 recordsLinked to original sources
PubMed1990

The problem of the taxonomy of the fusiform bacillus of acute necrotizing ulcerative gingivitis (Vincent's gingivitis).

The characteristic microscopic appearance of the fusospirochaetal complex in smears from patients with acute necrotizing ulcerative gingivitis has long been regarded as virtually pathognomonic of the disease. Unfortunately there is considerable confusion surrounding the taxonomy of the fusiform organism in the fusospirochaetal complex. The conflicting views appear to be irreconcilable and a re-evaluation of the taxonomy of oral fusiforms is urgently required.

Bacteroidaceae↗
PubMed1990

Oncocytic adenomas and oncocytic hyperplasia of salivary glands: a clinicopathological study of 26 cases.

Twenty-six benign oncocytic lesions of the salivary glands, excluding Warthin's tumours, have been reviewed and criteria for their classification as oncocytoma, multifocal nodular oncocytic hyperplasia, diffuse oncocytosis, pleomorphic adenoma with oncocytic change or oncocytic monomorphic adenoma have been proposed. The histological and clinical features of this heterogeneous group of lesions are discussed. This analysis suggests that the majority of lesions initially categorized as oncocytomas were, in fact, either non-neoplastic or, alternatively, oncocytic change in other types of adenoma.

Adenoma↗
PubMed1989

Infarcted ('infected') adenolymphomas. A clinicopathological study of 20 cases.

From a total of 323 adenolymphomas in the files of the British Salivary Gland Tumour Panel there were 20 cases (6.2%) which showed extensive necrosis, fibrosis and inflammation. The clinical and microscopical features of this distinctive subtype are described and it is suggested that infarction rather than infection is the more probable aetiological factor. In 40% of these infarcted adenolymphomas there was granuloma formation which mimicked tuberculosis or sarcoidosis and this possibility should be borne in mind when examining lesions in the parotid region.

Adenolymphoma↗
PubMed1988

Malignant myoepithelial carcinoma (myoepithelioma) arising in a pleomorphic adenoma of the parotid gland. An immunohistochemical study and review of the literature.

A 66-year-old woman presented with a giant tumor of the parotid gland, which under a light microscope had a sarcomatous appearance with spindle-shaped myoepithelial cells (malignant myoepithelioma). Histochemical examination showed longitudinal fibrils in the cytoplasm of the myoepithelial cells. Immunohistochemical studies showed positive staining for S-100 protein, vimentin, and actin in the myoepithelial cells. Cytokeratin was seen in the ductular epithelial cells and in the periductular myoepithelial cells, but it was absent from malignant myoepithelial cells. Ultrastructurally, these cells contained several longitudinally oriented slender structures resembling myofilaments without dense bodies. A review of the literature confirms the rarity of malignant myoepithelial carcinoma (myoepithelioma) arising in the parotid gland, and we therefore add another case.

Adenoma, Pleomorphic↗
PubMed1988

Nevus unius lateris and intraoral verrucous nevi.

A case of nevus unius lateris and two cases with similar intraoral lesions but no evidence of cutaneous involvement are described. The terminology of papillary intraoral epithelial nevi is discussed, and it is suggested that lesions of this type, confined solely to the mouth, should be called verrucous nevi.

Adolescent↗
PubMed1986

Lymphomas of salivary glands.

Primary lymphomas arising in salivary glands are very uncommon. The histologic classification of 40 cases of lymphomas in salivary gland tissue submitted to the British Salivary Gland Tumour Panel is reported, and, for 30 of the patients for whom adequate information was available, the clinical presentation, management, and outcome have been analyzed. Lymphomas in salivary glands represented 1.7% of all reported salivary neoplasms. The majority developed in the parotid glands of patients aged between 50 and 70 years. Only four cases gave a premorbid history compatible with sicca syndrome. In this series, non-Hodgkin's lymphomas predominated; 23 were Grade I, and 13 were Grade II. Treatment regimens were not uniform, but are outlined. Survival ranged from 5 to 111 months. Median survival for the group was 49 months. Prognosis was not influenced by the clinical stage of disease at presentation. Four cases of lymphoma arising in benign lymphoepithelial lesions are included. None had clinical symptoms of sicca complex. Prognosis for this group was found to be as favorable as the others.

Actuarial Analysis↗
PubMed1986

Warthin's tumor (cystadenolymphoma) of salivary glands. A clinicopathologic investigation of 278 cases.

This article reviews the detailed clinical and pathologic features of 278 cases of Warthin's tumor (cystadenolymphoma) from the files of the British Salivary Gland Tumor Panel. The tumor was found exclusively in the parotid gland, where it accounted for 14% of the total primary epithelial parotid tumors. The male predominance (1.6:1) was lower than in many earlier reports, and this observation is discussed. Some histopathologic features of both epithelium and stroma were semiquantified, and the presence of ciliated epithelium in a few tumors was confirmed. The Warthin's tumors were subclassified according to the scheme proposed by Seifert and colleagues. No examples of metaplastic Warthin's tumor were seen, but a few tumors were extensively necrotic and probably infarcted. The age distribution of patients with stroma-poor Warthin's tumor supported the concept that this variant develops by progressive adenomatous growth of typical Warthin's tumor. The histogenesis of Warthin's tumor is discussed briefly.

Adenolymphoma↗