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Biomedical subjects

R B Towbin

Publications and source records attributed to R B Towbin.

At least 91 records · Page 5Linked to original sources
PubMed1985

Precocious puberty following severe head trauma.

True precocious puberty is frequently secondary to intrinsic central nervous system pathology, but is rare following external head trauma. We describe two children who developed precocious puberty within three months of severe exogenous head trauma. Infusion of luteinizing hormone releasing factor induced a prompt rise in circulating gonadotropin concentrations and established that their sexual precocity was the result of premature activation of the hypothalamic-pituitary axis. While the precise mechanism by which exogenous head trauma causes precocious puberty remains unknown, the clinical features of these children's disorders are consistent with the hypothesis that extra-hypothalamic areas restrain pituitary gonadotropin secretion before puberty and that damage to these areas can result in precocious puberty.

Child↗
PubMed1985

Nonsurgical cure of brain abscess in a neonate.

A 7-day-old girl was found to have meningitis due to Staphylococcus aureus and a left parietal brain abscess. Six weeks treatment with intravenous methicillin resulted in resolution of her right hemiparesis and brain abscess. This is one of the youngest patients successfully treated by medical therapy alone. The case suggests that in carefully selected, closely monitored infants, medical therapy alone can be successful.

Brain Abscess↗
PubMed1985

Stubbed finger osteomyelitis.

Forceful hyperextension of the distal phalanx may result in a Salter II fracture. Due to the anatomic relationship of bone and nail, a 'stubbed finger' injury may result in an inapparent compound fracture. When nail bedding is associated with a distal phalangeal fracture, antibiotics should be instituted.

Adolescent↗
PubMed1985

Direct sagittal computed tomography of the head.

Direct sagittal computed tomography (CT) scanning of the cranium and face was facilitated using a fabricated to maintain the position of an adult patient's head on the scanner. A sponge was designed to fulfill the same purpose for children. Sagittal CT scanning of the head is easy to perform using these devices, and the additional equipment is inexpensive.

Adult↗
PubMed1985

Percutaneous aspiration, drainage, and biopsies in children.

Percutaneous aspiration, drainage, and biopsy techniques can be performed safely and effectively in infants and children. Over the past 4 years we performed 11 aspiration, nine drainage, and 14 biopsy procedures in patients aged 1 day to 17 years. Success was achieved in 88% and 93% of drainages and biopsies, respectively. Our experience suggests that aspiration and drainage procedures are effective in the diagnosis and management of fluid collections and are often the only procedure required and that percutaneous biopsy techniques are applicable to the pediatric population.

Abscess↗
PubMed1981

Retained fetal lung fluid in two neonates with congenital absence of the pulmonary valve and tetralogy of Fallot.

Chest radiographs obtained at birth in two neonates with absent pulmonary valve and tetralogy of Fallot demonstrated asymmetrical lung aeration. This finding was attributed to delay in resorption of fetal lung fluid. It is postulated that in the initial hours of life, the dilated pulmonary artery compressed the bronchus and delayed egress of fetal lung fluid. Over a 24-hour interval, the fluid was resorbed, resulting in the more typical pattern of hyperinflated lung and markedly dilated pulmonary artery. These cases are presumably the first of their kind to be reported.

Body Fluids↗
PubMed1981

Pediatric Legionnaires' disease: diagnosis by direct immunofluorescent staining of sputum.

Legionnaires' disease occurred in a 3-year-old boy with Down's syndrome. His illness was characterized by bilateral pneumonia, high fever, and response to erythromycin. The diagnosis was made by demonstrating Legionella pneumophila, serogroup 1, in sputum with a direct fluorescent antibody stain. L pneumophila antigen was detected in urine by an enzyme-linked immunospecific assay. The diagnosis was confirmed by a more than fourfold rise in serum antibody titer. Although Legionnaires' disease appears to be uncommon in children, it should be included in the differential diagnosis of pneumonia in the immunocompromised child.

Antibodies, Bacterial↗
PubMed1981

Tuberculosis in pregnancy with fatal congenital infection.

An unusual case of miliary tuberculosis which presented as fever and a tubo-ovarian abscess in a postpartum patient is described. Fatal congenital tuberculosis was also diagnosed in the mother's premature infant. The difficulties encountered in diagnosing the tuberculosis in these patients are summarized, and the need for early recognition and therapy is emphasized. Epidemiologic follow-up of the premature infant's exposed contacts was thorough and revealed no new cases of tuberculosis among the infants or the personnel who were exposed to the infected baby.

Abscess↗