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Biomedical subjects

R Bailey

Publications and source records attributed to R Bailey.

28 records · Page 2Linked to original sources
PubMed1978

Long-term consequences of respiratory disease in infancy.

In a study of Kent schoolchildren it has been shown that those who had a history of bronchitis under the age of five were more likely to have reported respiratory symptoms as the age of 11 (Bland et al., 1974). After this finding, it was necessary to test whether these differences would continue or diminish as the children grew older. One thousand three hundred schoolchildren in four areas of Kent were studied by physical examination and parental questionnaire at the ages of 5, 11, and 14. The relative risk of having reported respiratory symptoms for children with a history of early bronchitis, asthma, or pneumonia, compared with other children, was the same at the age of 14 as it was at the age of 11. These relationships could not be explained by social class effects, and were probably not due to parental bias in reporting.

Adolescent↗
PubMed1976

The interaction between prostaglandin E1 and delta 9-tetrahydrocannabinol on intestinal motility and on the abdominal constriction response in the mouse.

The interaction between delta9-tetrahydrocannabinol (THC) and PGE1 was studied using two pharmacological parameters-the rate of passage of a charcoal meal through mouse small intestine and the abdominal constriction response in the mouse. PGE1 administered intraperitoneally produced a dose-dependent decrease in intestinal motility, and this effect was antagonized by low (0.25 mg/kg) doses of THC and potentiated by higher doses of THC (1 mg/kg). Kinetic analysis suggested that the interaction was of a mixed but predominantly competitive type. PGF2alpha produced an increase in intestinal motility but this was not dose-dependent. THC antagonized the effect of PGF2alpha in a dose-dependent manner suggestive of a physiological antagonism. THC (0.25-2 mg/kg) antagonized the dose-dependent PGE1 abdominal constriction response in a fashion which suggested a mixed (though mainly competitive) antagonism. It would ssem, therefore, that on the two pharmacological parameters studied THC appears to be interacting with PGE1 at the same receptor site. Although the doses of THC used are within the range of those used in man, it is not implied that these results are necessarily implicated in the psychoactivity of the drug.

Analgesia↗
PubMedDate not supplied

Trachoma and water use; a case control study in a Gambian village.

Trachoma is prevalent in many arid areas but data assessing the relationship between water use and trachoma are very scarce. This study compared 18 families having one or more active trachoma cases among the children with 16 trachoma-free families in the same village with respect to water use. Potential confounders such as family size, distance to water source, socio-economic indicators, and hygiene behaviour were assessed in the 2 groups. The families with trachoma were found to use significantly less water per person per day for washing children than did the control group (P = 0.033) with no evidence of confounding by the other measured variables. Low amounts of water for washing were also associated with unclean faces and impetigo in the children. If such a relationship can be substantiated it might provide the basis for effective and cheap interventions against trachoma.

Adolescent↗
PubMedDate not supplied

Traumatic amputations. A vietnam experience.

Ninety-two acute combat amputations were performed in 70 casualities of the Vietnam conflict. In the 67 surviving patients with 83 stumps, primary closure was done in 24 limbs (30%) and delayed closure in 11 more. Closed cases were observed 2 weeks and no failures noted. In selected patients early suture of war amputations can be practiced with a satisfactory result.

Adolescent↗
PubMedDate not supplied

Fat embolism syndrome following total hip arthroplasty.

This is a case report of total hip arthroplasty in a healthy 38-year-old woman with the unusual complication of fat embolism with no evidence of hypotension or other intraoperative incidence. Prompt recognition of fat embolism and appropriate supportive therapy resulted in the successful resuscitation of the patient and an excellent functional hip joint.

Adult↗