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Biomedical subjects

R Buchholz

Publications and source records attributed to R Buchholz.

At least 55 records · Page 3Linked to original sources
PubMed1977

[Studies on the dependence of intrafollicular pressure on the pressure in the intraovarian-vascular-system and tissue, carried out in vitro on human ovaries (author's transl)].

The intrafollicular, intraovarian and intraarterial hydrostatic pressures were measured in vitro on human ovaries in the vollicular ripening phase. It has been established that in the vascular system as well as in the intraovarian tissues pressure variations occur spontaneously. Thus for example under, the influence of epinephrine, norepinephrine, prostaglandine F2 alpha and oxytocine, the tonicity of the vascular system increases and does so the number of spontaneous contractions rather noticeably, particularly under the influence of prostaglandine F2alpha, and under the various catecholamines an increase of frequency and amplitude has been observed. Any increase of pressure in the intraovarian vascular system and tissues will effect all the follicles not yet in the preovulatorian phase, in which they cause a similar pressure increase. However, follicles imminently preovulatorian have not shown such pressure increase because the increase of the "liquor folliculi" runs parallel to the increasing elasticity of the follicle walls. The findings are discussed in this article with a particular view of the biophysical aspects of ovulation.

Adult↗
PubMed1977

[Ultrasonics of ovarian changes under gonadotrophine stimulation (author's transl)].

It is known that there are difficulties in timing of ovulation induction under gonadotrophines. The reason is that investigation parameters used so far only permit indirect quantitative statements. Ultrasonics permit the direct presentation of ovaries, cystic structure-follicles, registration of their number and size as well as control of the further development. Using an typical case, possibilities with ultrasonics are demonstrated. Ovulation was induced when one follicle (0 23 mm) dominated over two others (0 17 mm), and a corpus-luteum-cyst and the pregnancy were observed. Two gestational-sacs perished during bleedings in the 9th week of pregnancy. The normal pregnancy was controlled with ultrasonics until delivery. Ultrasonic equipment was Vidoson 635 S by Siemens and Diasonograph NE 4102/B by Nuclear Enterprises.

Chorionic Gonadotropin↗
PubMed1976

Investigations into the preservation of human ovaries by means of a cryoprotectivum.

Human ovaries in the phase of follicular ripening were treated by means of a cryoprotectivum immediately after their removal. They were kept at --18degrees C for up to 8 weeks. After having gradually been thawed the ovaries were in vitro connected to a perfusion system. When completely revitalized they were examined in the steady-state for their metabolic behaviour. It was found that in comparison with the untreated controls, depending on the period of preservation, the oxygen consumption and the estrogen secretion had decreased, while the glucose absorption and lactate production had increased. As a morphological substrate a minor oedema was established in the tissue in the histological control after a preservation period of 2 months. This was mainly localized around the arteries. The method can be regarded as suitable for the preservation of ovaries for a limited period of time. It is possible to maintained a metabolism that can still be regarded as functioning.

Adult↗