[Neurocardiogenic syncope].
Explore the source record for details and available documents.
Adrenergic alpha-Agonists↗
Biomedical subjects
R Cai
Publications and source records attributed to R Cai.
[Primary non-Hodgkin's malignant lymphoma of bone in 5 patients].
The authors report here 5 cases of primary non-Hodgkin's malignant lymphoma of bone. All bones of the body can be involved, but the commonly inflicted ones are pelvis and femur. This kind of lymphoma possesses no special clinical features and X-ray manifestation, so it is very difficult to be diagnosed and easily misdiagnosed. The diagnosis can be made with the following 5 items: (1) local significance; (2) X-ray manifestation; (3) bone origination; (4) the no proof of originating from other tissues; and (5) pathological examination. This kind of lymphoma is mainly treated with radiotherapy, and adjuvant surgical treatment and chemotherapy are sometimes given.
Adult↗
[Experimental study on in vivo hematopoietic regulation of interleukin-6 gene therapy].
Interleukin-6 (IL-6), a pleiotropic cytokine, is involved in extensive immune regulation and hematopoietic regulation. We observed the effect of fibroblast mediated human IL-6 gene therapy on hematopoiesis. The platelet counts started to increase at day 4 after implantation of IL-6 highly secreting fibroblast cells and peaked at day 10 and lasted at high level for 22 days. The neutrophil counts were elevated after their implantation, but WBC did not show any remarkable increase. The CFU-GM and CFU-MK in bone marrow and spleen were also increased significantly. The results demonstrated that fibroblasts mediated human IL-6 gene therapy can significantly augment in vivo hematopoietic functions in bone marrow and spleen and elevate the number of nuetrophils and platelets. This study provides a new approach to treat thrombopenia and chemotherapy or radiotherapy-induced hematopoietic suppression.
3T3 Cells↗
Photokilling of T-24 human bladder cancer cells with titanium dioxide.
A photoexcited titanium dioxide surface has a strong ability to decompose water into hydrogen and oxygen. We have studied this effect in order to use it to kill cancer cells in vitro and in vivo. A distinct cell killing effect was observed on cultured T-24 human bladder cancer cells treated with titanium dioxide particles and 300-400 nm UV light irradiation. Titanium dioxide plus UV light also dramatically suppressed the tumour growth of T-24 cells that were implanted in nude mice. Cells cultured on the titanium dioxide electrode were also killed under UV irradiation when the electrode was anodically polarised, suggesting that photogenerated holes are involved in the cell killing. The cell killing effect caused by titanium dioxide particles plus UV light irradiation was significantly hampered in the presence of L-cysteine and catalase, scavengers of hydroxyl radicals and hydrogen peroxide respectively. Transmission electron microscopic observations showed the titanium dioxide particles to be distributed on the cell surface and inside the cells. These results suggest that titanium dioxide particles under UV light irradiation produced photogenerated holes on the surface yielding hydroxyl radicals and hydrogen peroxide inside or outside the cells and the cells were then killed by the action of these highly oxidising molecules. The possible application of photoexcited titanium dioxide particles to cancer treatment as a new anti-cancer modality is discussed.
Catalase↗
[Isolation, purification and the characteristics of 70 KD pronucleation glycoprotein in the bile].
In recent years, the great achievement in the etiology of cholelithiasis is the discovery of pro- and anti-nucleating factors in human bile. Using Con-A affinity chromatography combined with Sephadex G-200 molecular sieve technique, we have isolated and purified a strong pronucleating glycoprotein in gallbladder bile. Its molecular weight is 70KD, the quantity ratio of neutral hexose to protein in this glycoprotein is 15.88%. One molecule has about 640 amino acid residues. Its N-terminal amino acid sequence is N-Ser-His-Gly-Met-Arg-Gln-Tyr-Tyr-Met-Lys. The pathogenic and biological significance of this glycoprotein in the pathogenesis of gallstone were discussed.
Amino Acid Sequence↗
Clinical assessment of biplanar transesophageal echocardiography--a report of 125 cases.
One hundred and twenty-five patients with cardiovascular disease were examined by biplanar transesophageal echocardiography (BTEE), including 67 with rheumatic heart disease (7 monitored during operation), 22 with aortic diseases, 20 with congenital heart diseases, and 16 with other kinds of heart disease. The results showed that BTEE was not influenced by corpulent and pulmonary emphysema and was better than transthoracic echocardiography at imaging the interatrial septum, left atrium and left atrial appendage, thoracic aorta, and mitral artificial valve and at intraoperative monitoring. BTEE was also better than single-plane transesophageal echocardiography, because BTEE could be used to observe the heart and thoracic aorta in transverse and longitudinal planes, thus enlarging the transmission "window" as well as allowing the entire lesion to be imaged. This study suggests that BTEE will have good prospects in clinical application.
Adolescent↗
Induction of cytotoxicity by photoexcited TiO2 particles.
Photoexcited TiO2 particles can drive various chemical reactions due to their strong oxidizing and reducing ability. To investigate the possible use of this effect for cancer treatment, the antitumor activity of photoexcited TiO2 particles was studied in vitro and in vivo. HeLa cells cultured in vitro were completely killed in the presence of TiO2 (50 micrograms/ml) with 10-min UV irradiation by a 500-W-Hg lamp. In contrast, very little cell death was observed from TiO2 treatment without UV irradiation. Photoexcited TiO2 particles also significantly suppressed the growth of HeLa cells implanted in nude mice, compared with those receiving TiO2 alone or UV irradiation alone. The cell death caused by photoexcited TiO2 particles was significantly protected in the presence of L-tryptophan and catalase. These molecules are quenchers of hydroxyl radicals and scavengers of hydrogen peroxide, respectively, suggesting that the cells were killed by the OH. and H2O2 produced from photoexcited TiO2 particles.
Animals↗
Prolongation of pancreaticoduodenal allograft survival in rats by treatment with FK 506.
Explore the source record for details and available documents.
Animals↗
Effects of genetic factors and dietary electrolytes on blood pressure of rural secondary school students in Hanzhong.
In this study, 24-h urine specimens were collected on 3 consecutive days from 181 adolescents (94 boys and 87 girls), aged 12-16 years, in a rural district--Hanzhong, Shaanxi Province, and sodium, potassium, calcium and magnesium levels were determined. Dietary intake of the four electrolytes and blood pressure were measured in children and their parents on the same consecutive days. The results were as follows: urinary output of calcium and magnesium might not be an appropriate index to reflect intake; after adjusting for age, sex, BMI, heart rate, and parental blood pressure, the ratio of dietary calcium to total calories was negatively related to diastolic blood pressure in the whole group, and the ratio of urinary calcium to creatinine was positively related to systolic blood pressure in girls; not only blood pressure but also its relation to electrolytes are affected by parental blood pressure after adjusting for age, sex, BMI and heart rate.
Adolescent↗
[Study on correction of abnormal fetal position by applying ginger paste at zhihying acupoint A. Report of 133 cases].
Applying fresh ginger paste at Zhihying acupoint before retiring, we treated 133 pregnant women (28 to 38 weeks' gestation) with breech position. There were 118 primigravidas. 238 untreated pregnant women (28 to 32 weeks' gestation) with breech position made up the control group. 113 out of the treated pregnant women had normal fetal position after treatment with 77.4% of correction rate. 48 out of the 113 pregnant women whose fetal position corrected by treatment only received once therapy, accounting for 42.5% of cured cases. Spontaneous correction of fetal position happened in 123 pregnant women of the control group with 51.6% of correction rate. There was a significant difference in the correction rate between study and control groups. (P less than 0.01), suggesting that this therapy is easy, economical, safe, and suitable to popularization at the basic level.
Acupuncture Points↗