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Biomedical subjects

R Choux

Publications and source records attributed to R Choux.

At least 91 records · Page 5Linked to original sources

[Light and electron microscopy in one case of herpes zoster keratitis (author's transl)].

One case of herpes zoster keratitis studied after corneal graft is described. Light and electron microscopy investigations show severe pathological changes under the coneal epithelium: Bowman's layer disruption, superficial stromal alterations, sub-epithelial phagocyte proliferation with lipid and mucopolysaccharid vacuolar deposits, abnormal vascularization of the posterior stroma. The authors stress on this interesting ultrastructural study because of very rare cases of the same disease reported in the literature.

Cornea↗

[Craniostenoses].

Explore the source record for details and available documents.

Age Factors↗

Inorganic cytoplasmic inclusions in alveolar macrophages. The role of cigarette smoking.

A case of tobacco-associated pulmonary fibrosis, with the results of histological, ultrastructural, and spectrometric analysis is reported. Abnormalities of the alveolar macrophages, which are particularly affected by tobacco inhalation were found. The size of the macrophages was increased and many large, polymorphous inclusions, including fat vacuoles and granular deposits, which were either homogeneous or electron lucent vacuoles, were seen in the cytoplasm. A few laminar structures were observed. All of these lesions are frequently found in cigarette smokers. Still more interesting was the discovery of numerous fiber-, needle-, or laminar-like inclusions that varied in size from 0.2 to more than 2 mu. The digestions of the inclusions with potassium hydroxide confirmed the presence of various metals, such as sodium, magnesium, potassium, iron, sulfur, and especially, aluminum, and silicon; these last two elements correspond to the presence of kaolinite in the tissue, as has been previously described, and can be considered as evidence of the use of tobacco.

Aged↗

[Synovialo-sarcoma of the laryngopharynx: electron microscopic study (author's transl)].

The authors report a new case of synovialo sarcoma of the laryngo-pharynx by optic and electron microscopy. Ultrastructural features were similar to those of joint synovialo-sarcoma, i-e, showing glandular like and spindle cell componments. Both of these shared several ultrastructural characteristics, favouring the hypothesis of a common origin. The site and the fine structure of this tumor are discussed according to the literature.

Adult↗

[Olfactory esthesioneurocytoma: ultrastructural study of a case (author's transl)].

One case of malignant tumour of the left nasal cavity is reported in a woman 56 year old, affected by the disease 24 years. Numerous recurrences appeared and various histological diagnoses were performed. At the last surgery, the tumour invaded the ethmoid and was a typical olfactory esthesioneurocytoma. By electron microscopy, mature ganglion cells with dense cored vesicles (neurosecretory granules) were densely packed. Neuritic processes with microtubules were rarely normal in size and their content was most often abnormal; furthermore dystrophic axons were noted in great number.

Axons↗

[Cerebral hemangiopericytoma. Ultrastructural study of one case].

The authors report electron-microscopic observations upon a primitive cerebral haemangiopericytoma. The vascular appearance of the tumour is due to the presence of abundant extracellular material which has a structure like that of vascular basement membranes. The fact that the tumour cells are pericytes is confirmed by the existence of intracytoplasmic microfilaments of 60-80 A in diameter, sometimes gathered into osmiophilic aggregations and forming simple cellular junctions (zonulae adherentes). Stress is laid upon the importance of differentiating this rare tumour from an angioblastic meningioma; the haemangiopericytoma is more rapidly growing and carries a more serious prognosis.

Adult↗

Diagnostic and therapeutic problems concerning tumors of the vault.

We observed 36 tumors of the cranial vault in children (11 epidermoid and dermoid cysts, 3 meningiomas, 3 malignant tumors, 11 vascular tumors, 6 eosinophilic granulomas, 2 osteomas). The common clinical finding enabling us to include all 36 tumors in this study is a large tumefaction of the cranial vault, without our being able to determine its anatomical starting point or histological nature. These observations are described according to whether they have a bony, dural or cutaneous origin, differentiating tumors of embryological origin. In the majority of cases, internal and external carotid angiography was performed to help surgery, which remains the only cure.

Adolescent↗

[Benign asbestosic pleurisies (apropos of 3 cases)].

Report is made on three cases of benign asbestosic pleural effusions that occured in subjects of more than 60 years in age that had had moderate but long occupational contact with asbestos (between 18 and 40 years). We are dealing here with pleural effusions that have an insidious onset and a chronic course, serofibrinous in nature for the three cases, moderately exsudative, with a relatively few accelerated blood sedimentation rate, a level of protids between 34 and 58 g/l and a level of dextrose between 0,70 and 1,15 g/l. Relapses were noted in two of the patients. In two of these cases existed associated pleural calcifications. Important sequelae persist after the cure that consist in pachypeuritis, and one of these cases was submitted to surgery. Confirmation of the diagnosis was found in the surgical material that contained asbestosic bodies; the sputum of the same patient contained also ferruginous bodies. The research of an occupational contact with asbestos has to be systematically performed in the case of subjects that exhibit, after a certain age, an apparently cryptogenetic pleural effusion.

Aged↗

[Pleural biopsies: complications and current value of Abram's needle biopsy. Apropos of 1,000 samples. Value of pleuroscopic biopsy].

The frequency of incidents resulting from Abrams needle biopsy is very low provided certain contraindications are respected : pneumothorax, 3.1% of cases ; hemorrhages, 1.3% ; neoplastic contamination of the bioptic tract, 1.9%. Serious accidents are rare. We only observed 2 serious hemorrhages, one in 1964, the other in 1968. In the latter case, the pleural hemorrhage caused a very serious respiratory insufficiency. The delayed functional reaction is still not well known. However the occurrence of immediate accidents could reflect on radiological sequelae. The value of this examination seems today to decrease slightly at the same time as the frequency of pulmonary tuberculosis decreases. Indeed pulmonary tuberculosis is the main indication for this method because of the history and because of the possibility of culture on Loewenstein medium. In cancer, needle biopsy has two drawbacks, that of being blind and yielding only small samples, while pleuroscopy is free of them. In a series of 77 examinations including 45 cancers, the positivity reached 80%. In only 2 cases did pleuroscopy give a falsely positive result. In the remaining cases there was no neoplastic invasion of the pleura.

Biopsy, Needle↗