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Biomedical subjects

R Cocchi

Publications and source records attributed to R Cocchi.

At least 55 records · Page 3Linked to original sources
PubMed1979

[Experience with detoxification and weaning of heroin addicts by means of acupuncture, gabergic drugs and psychopharmacologic agents in low doses].

UNLABELLED: Presents extensive reports of detoxification and habit loosing trials in 9 male heroine addicts, 19-26 yr. The therapeutic programs were centered on gabergic drugs, low doses tricyclic antidepressants and benzodiazepines, and acupuncture (main points: 8 GB; nasal GB; 1 GB; 3 L; 4 LI; 36 S; 7 H; auricular Shen men) and were continued weekly at the Mental Health Outpatients Service, after discharge from the hospital. RESULTS: 2 Ss, personally checked, abstinent 6 months after their discharge; 4 Ss heard as abstinent and 3 Ss relapsed. Technique, course and times of the therapeutic program seem to be one of the key factors for success.

Acupuncture Therapy↗
PubMed1978

[Acupuncture, "vital" drugs and psychotropic agents in psychiatric patients. 50 cases].

A therapeutical trial by means of acupuncture and "vital" drugs (1-glutamine and N-dipropylacetic acid) in 23 out of 50 psychiatric chronic patients basically depressive, and by means of acupuncture, vital drugs and psychodrugs in the remaining 27 similar patients, is carefully reported. 49 of this patients got improvement, 41 of them in a middle degree. The different neurochemical curcuits (GABA-ergic, glutamergic, adrenergic, noradrenergic, serotoninergic and dopaminergic) put in balance by such therapeutical association have been discussed.

Acupuncture Therapy↗
PubMed1977

[Acupunctura, "vital" drugs and psychopharmacological agents in the treatment of psychiatric patients with deep depressive disorders, with considerations on the probable neurophysiological mechanisms of the synergism of action].

Personal clinical experience in 36 psychiatric patients with true or masqued depression, receiving a combined treatment of acupuncture (in traditional and auricolar suprarenalic points), "vital" drugs (DPA 300-900 mg/die; l-glutamine 250-500 mg/die) and psycho-drugs (amitryptiline 50 mg/die; clomipramine 10-30 mg/die; diazepam 2-20 mg/die; haloperidol 2 mg/die) is described. 35 out of 36 cases improved by such therapy. Possible synergic mechanisms leading to a considerable reduction of usual phychodrugs, and attenuating or eliminating various side effects are finally discussed.

Acupuncture Therapy↗
PubMed1977

[Psychological dependence? A possible different formulation of the problem for a therapeutic rearrangement in chronic drug addictions].

Disputing the concept of "psychic dependence", the Authors review six motivations to use addictive drugs, four of which pertain to the moment to assume the habit, although the latter two, which are identifiable with physical and psychic dependence, depend on te breaking the habit. While physical dependence is linked to withdrawal syndrome, psychic dependence, on the Author's opinion, is related to a long-standing previous state of true or masked endogenous depression (in this case it would be well termed as "neuropsychological dependence"), and the drug taking is only a maladaptive self-medication. This thesis is substantiated by the literature, reporting, in chronic drug addicts the use of the whole series of antidepressants (i.e. tricyclics, doxepine, lithium, etc.), with noticeable therapeutical success. According with other reports and with personal experience, the Authors maintain a great importance to drugs acting, directly or not, on GABA, i.e. l-glutamine, piracetam, and, particularly, N-dipropilacetic acid.

Antidepressive Agents↗
PubMed1977

Psychic dependence? A different formulation of the problem with a view to the reorientation of therapy for chronic drug addiction.

Disputing the concept of "psychic dependence", the authors review six motivations to use addictive drugs, four of which pertain to the moment of assumption of the habit, and two of which, identifiable with physical and psychic dependence, depend on breaking of the habit. While physical dependence is linked to withdrawal syndrome, psychic dependence, in the authors' opinion, is related to a longstanding previous state of true of masked endogenous depression (in this case it would be well termed "neuropsychological dependence"), and the drug taking is only a maladaptive self-medication. This thesis is substantiated by the literature reporting, in chronic drug addicts, the use of the whole series of antidepressants (i.e. tricyclics, doxepine, lithium, etc.) with noticeable therapeutical success. In accordance with other reports and with personal experience, the authors assign great importance to the drugs acting, directly or indirectly, on GABA, i.e. L-glutamine, piracetam, and, particularly, N-dipropylacetic acid.

Aminobutyrates↗
PubMed1977

[1-glutamine and dipropylacetic acid as subsidiary psychotropic agents in the treatment of psychiatric in-patients. Effect on the neuroleptic consumption].

In a division of the neuropsychiatric hospital of Racconigi, with acute and chronic inpatients, the use of 1-glutamine and N-dipropylacetic acid as subsidiary psychodrugs, after one year follow-up, showed to have reduced the whole administration of neuroleptics, without diminishing the therapeutic efficacity. This administration, during the four sampler months (December, March, June and September), face with the sames of the preceding year, has been lesser than 29,04% (lesser than 38,21%, if we take into consideration the last two months). Such result has been confirmed by a corresponding diminution of orphenadrine, the drug used to counteract the neuroleptic syndrome, which during the last two months considered in this research, respectively subsided of 28,57% and 36,36%.

Clinical Trials as Topic↗
PubMed1975

[Studies on the diagnostic value of various enzymatic activties in icterogenic hepatitis of infancy. II. Sorbitol dehydrogenase, guanase and argininosuccinate lyase].

The AA. have determined the levels of argininesuccinatolyase (ASAL), sorbitoldehydrogenase (SDH) and guanase (GUA) in 65 cases of hepatitis of infancy, by comparison with the corresponding levels of transaminases. Of all the enzymes examined, transaminases were the most sensitive sign of liver damage, not only because of their more pronounced rise in the earlier stages of the disease, but also in consideration of their slower regression to normal values. The AA. nevertheless believe that a special significance can be assigned to the determination of SDH for its persistency to levels higher than the normal ones in prolonged hepatitis, and for its quick increase in the recurrences; its regression to normal values may be assumed as an early and clear sign for the demonstration of the stages indicative of recovery.

Adolescent↗
PubMedDate not supplied

Longitudinal assessment of body composition in CAPD patients using bioelectric impedance analysis. A comparison with hemodialysis patients.

The utility of bioelectric impedance analysis was assessed for longitudinal evaluation of body composition in two groups of uremic patients, one on CAPD and one on hemodialysis treatment, with no clinical marks of hyperhydration or infection. Nineteen CAPD patients (11 men 8 women) and 21 HD patients (12 men 9 women) were studied with bioelectric impedance analysis for a period of 12 months; total body water, fat free mass, and fat mass were calculated from bioelectric impedance analysis data of resistance and reactance at time 0 and 12 months later. No significant differences in body composition were found in the two groups at time 0 and 12 months later, with a similar trend for total body water, fat free mass, and fat mass. In CAPD, a significant increase in body weight was observed due mainly to a rise in fat mass, particularly evident in women with uremia. Bioelectric impedance analysis appears to be an instrument easily repeatable and reliable in CAPD and HD patients, reflecting at the same time body composition, the dialytic adequacy of a technique, and the patient's well being.

Adipose Tissue↗