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Biomedical subjects

R Günther

Publications and source records attributed to R Günther.

At least 217 records · Page 12Linked to original sources

[Results of post mortem thyroid gland phlebography (author's transl)].

The anatomic course and variation of the thyroid veins used for retrograde thyroid phlebography were studied in 70 post mortem thyroid phlebograms. Comparison with pathological and anatomical findings showed good agreement in benign diseases of the thyroid with lesions of more than 1 cm. Infiltrating malignant changes could not be delineated with certainty and a post mortem proven parathyroid adenoma was also missed. The practical clinical significance of thyroid phlebography is therefore confined to the localisation of parathyroid tumours in primary hyperparathyroidism by selective parathoromone measurements.

Adenoma↗

[Thyroid phlebography and selective venous sampling for parathormone estimations in primary hyperparathyroidism (author's transl)].

Selective venous sampling for parathormone estimations has become an important method in the diagnosis of primary hyperparathyroidism and, together with thyroid phlebography, is an accurate means for localising hormone active parathyroid tissue. Thirty-three patients were examined by this technique and in 25 of these an exploration was carried out subsequently. Twenty-one had primary hyperparathyroidism. In one case hormone analysis lead to a false positive finding. In 18 of these 21 patients, the hormone-active parathyroid tissue was correctly localised. Phlebography showed evidence of an adenoma in five patients, but is of most use for localising the source of the hormone.

Adenoma↗

[The results of transvenous cholangiography (contrast media)].

Transvenous cholangiography is a method for the direct demonstration of the biliary passages described by Hanafee and Weiner; its main indication is in the investigation of obstructive jaundice. This method, which does not require immediate subsequent operation, was used in 41 patients. In three patients catheterisation of hepatic veins was unsuccessful. Of the remaining 38 patients, puncture of a bile duct was successful in 20. In 29 patients biliary obstruction was present, and this was demonstrated in 19. In the absence of obstruction the procedure was successful in only one case. The main complications were a sub-capsular liver haematoma, with rupture into the abdominal cavity and one case of haemobilia.

Catheterization↗

[Localization diagnosis of epithelial-body tumors through selective determination of parathyroid hormone. Surgical sequelae of a new method].

A new method for the localisation of abnormal parathyroid tissue is reported. This is carried out by selective venous blood sampling from the thyroid veins and the large veins of the neck. Parathyroid hormone levels are measured by radioimmunoassay. The peak hormone level indicates the site of the tumor suspected. Parathyroid venous blood was taken in 15 patients with primary hyperparathyroidism. In 12 patients localisation of the parathyroid tumor was achieved pre-operatively. The procedure is especially valuable in patients with previous unsuccessful parathyroid surgery. There are no complications or contraindications to the method.

Adenoma↗

[Technique and results in adrenal phlebography (author's transl)].

Following a brief description of the anatomy of the adrenal gland the technique of adrenal phlebography is explained. So far this method has been used in 118 patients. This examination is indicated in cases with suspected hormon - active disease of the adrenal glands and to rule out spaceoccupying lesions as well as metastases in the adrenal gland. Characteristic radiologic findings are demonstrated. Causes for complications of this method and their possible prevention are discussed.

Adenocarcinoma↗

[Selective parathormone determination for localizing parathyroid tumors].

A method for localization of parathyroid tumors by selective venous blood sampling and measurement of parathyroid hormone is reported. The blood samples are taken after catheterization of the femoral vein from the veins of the neck and the thyroid gland. Parathyroid hormone levels are measured by radioimmunoassay. By this method localisation of 13 parathyroid adenomas in 15 patients was achieved. Parathyroid venous sampling seems to be more effective than any other localisation method used.

Adenoma↗