Biomedical subjects

R Gao

Publications and source records attributed to R Gao.

At least 109 records · Page 6Linked to original sources

PubMed1993

[Fundus fluorescein angiographic findings of sympathetic ophthalmia].

Eight cases of sympathetic ophthalmia diagnosed by histopathologic examinations of the enucleated exciting eyes were collected and the fundus fluorescein angiographic (FFA) findings of the sympathized eyes in acute stages were analyzed. The manifestations of the FFA were divided into three types. We suggest that if one eye has a history of trauma and the other eye loses visual acuity rapidly accompanied with uveitis signs after certain incubation period, the fundus fluorescein angiography should be examined to achieve a clinically objective diagnostic basis so that the patients are treated in time.

Adult↗

PubMed1993

[Observation on the relation between propagated sensation along meridians and the therapeutic effect of acupuncture on myopia of youngsters].

Nine hundred and ninety two eyes suffering from various degrees of myopia in 536 youngsters were treated with acupuncture. A method of exciting propagated sensation along meridians (PSM) and making it travel toward the affected region was employed in treatment. Bilateral Hegu (LI4) and Taichong (LR3); and bilateral Waiguan (ST5) and Guangming (GB37) were punctured on alternate days. The results showed that after 1-3 periods of treatment, the vision of 868 eyes (87.5%) were improved in various extent. Among them, the vision completely recovered in 131 eyes (13.31%), and the diopter decreased-0.75 to -1.00 D.S. in 13 eyes after acupuncture treatment. The therapeutic effect of acupuncture seemed to be considerably satisfactory and stable in two years following up. The extent of distinctness of PSM raised markedly with the increase of times of acupuncture. There was a close relation between the extent of distinctness of PSM and effectiveness of acupuncture. The more striking the centripetal PSM, the better was therapeutic effect of acupuncture. The excellent effect was always achieved when PSM arrived at the affected eye. Since PSM arrived at a large number of eyes in the subjects in younger year and so the better therapeutic effect was also achieved.

Acupuncture Therapy↗

PubMed1993

Study on application of the silicone oil in the reattachment of complicated retinal detachment.

Sixty eyes with complicated retinal detachment were treated by vitrectomy combined with silicone oil tamponade (27 eyes of PVR grade D, 15 eyes of giant retinal tears with posterior flat folded-over, 13 eyes of posterior or macular hole, 5 eyes of traumatic PVR). After 3-24 months follow-up, the study showed retinal anatomic reattachment in 48 eyes in which the visual acuity of 32 eyes was 0.05 or better. The authors consider that vitrectomy and peeling make the silicone oil tamponade perfect the vitreous surgery and improve the successful rate. The theory of silicone oil tamponade, the indications, advantages and disadvantages of silicone oil tamponade are discussed in this paper.

Adolescent↗

PubMed1992

Misclassification of exposure in a case-control study: the effects of different types of exposure and different proxy respondents in a study of pancreatic cancer.

This investigation addressed three questions about misclassification in a case-control study of risk factors for pancreatic cancer in which all exposure data were obtained from proxy respondents. These questions were: (1) To what degree was misclassification dependent on the type of exposure? (2) To what degree did misclassification vary by the type of proxy? (3) What was the magnitude of the effect of proxy misclassification on odds ratios measured across several levels of exposure? To answer these questions, we interviewed 163 control (index) subjects and next-of-kin (proxy) respondent pairs. Each of the controls and their respective proxies reported the control's use of coffee, cigarettes, and alcohol and weekly exposure to beef, milk, bacon, fruits, and vegetables. Nonspouse proxies misclassified exposures more than spouse proxies with the exception of cigarettes. Cigarette use was the most accurately reported exposure, followed by alcohol, coffee, and foods. For nondifferential misclassification between cases and controls, the slope of a dose-response curve was decreased from 6.6% to 100% depending on the exposure and the type of proxy respondent. Investigators conducting studies using proxy respondents need to recognize that misclassification is a function of multiple factors, including both the type of exposures under study and the type of proxies available.

Adult↗

PubMed1992

The electrophysiology in idiopathic senile macular hole.

Of 12 patients with idiopathic senile full-thickness macular hole, 3 had bilateral involvement, 9 had monocular macular hole. Flash ERG and pattern VEP were performed in the bilateral eyes of all patients. The abnormal rate of the pattern VEP was 93.3% when we used 15' checkboard stimulus, the changes of the VEP appeared as delayed latencies, reduced amplitudes or malformation of P100. The abnormal rate of the flash ERG was 53.3%, showing primary characteristics of reduced amplitudes of cone response b-wave. There was statistically significant difference between the abnormal rates of the VEP and the ERG (P < 0.05). The halo diameters of the macular hole were significantly related to the latencies of P100 (P < 0.01), but there was no correlation between the hole diameter and the latencies of P100. In 9 fellow eyes which did not form macular hole, 3 eyes had the abnormal pattern VEP, including one eye having formed macular cyst. The results show that, in idiopathic senile macular hole, the pattern VEP provides more functional information than does the ERG, and prompts the importance of close follow-up of fellow eye.

Aged↗

PubMed1992

[Microvitreoretinal surgery for management of giant retinal tears with posterior flat folded-over].

Twelve cases (12 eyes) of giant retinal tears with posterior flat folded-over were treated using vitrectomy, membrane peeling, and air or silicone oil tamponade. The operations were successful in 4 of the 5 cases of silicone oil tamponade group and in 2 of the 7 cases of air tamponade group. All the successfully operated eyes (6 eyes) had a visual acuity of 0.05 or better. We believe that vitrectomy makes it possible for the folded-over and fixed retina to recover mobilization and return to its normal anatomic position.

Adolescent↗

PubMed1992

[Vitreous surgery for retinal detachment with severe proliferative vitreoretinopathy and probe of failed cause].

Eighty-one cases (81 eyes) of retinal detachment with severe proliferative vitreoretinopathy were treated using vitrectomy, scleral buckling and air or silicone oil tamponade technique. After a follow-up period of 6-28 months, 54 cases obtained anatomic retinal attachment (66.7%). For the serious cases of PVR D3, we also gained a success rate of 50%. Vision improved in 50 cases, whereas 34 cases got a vision better than 0.05. For the failed cases, cause that prevent the retina from attachment was probed. We think that vitrectomy is an essential and important procedure for retinal detachment with severe PVR, membrane peeling is the key of success and prevention of reproliferation can avoid recurrent retinal detachment and further raise the success rate of treatment. A new classification is recommended in this article.

Adolescent↗

PubMed1992

[Micro-vitreoretinal surgery for failed common retinal detachment repair].

In this paper we analyzed 49 cases (49 eyes) of micro-vitreoretinal surgery for failed common retinal detachment repair. Reattachment was achieved in 37 cases (75.51%) and final visual acuity of 10/200 or better was attained in 32 cases (65.31%). It was suggested that common operation failure in these patients was due to PVR. Cryopexy, diathermy and repeat operation can render the formation of the PVR. Micro-vitreoretinal surgery should be performed on these patients. There was a linear relationship between the effectiveness and the degree of PVR. It is best to perform the surgery 3 months after common operation. Finally, the authors discuss the reasons for failure of vitreoretinal surgery and conclude that the anterior PVR and the invalid fixing are the main reasons for failure of vitreoretinal surgery.

Adolescent↗

PubMed1992

[The operation treatment for the age-related macular degeneration wet-type eyes and its complications].

Age-related macular degeneration (AMD) is one of the important causes for blindness in elderly population. The effect of the treatments by laser and vitrectomy in AMD wet-type eyes, which subretinal neovascularization is existed in or have vitreous hemorrhage, is reported and discussed. Using laser photocoagulation, 65% of the affected eyes had marked cicatrization and 31% were partially improved. Among the 4 AMD eyes with vitreous hemorrhage, three cases were successful after vitrectomy. It has a certain significance for rescuing the vision and controlling the development in AMD wet-type eyes.

Aged↗

PubMed1992

Hemodynamic observation and treatment approach for patients with angina decubitus.

In order to investigate the mechanism and treatment of angina decubitus, 20 patients (18 men and 2 women aged 36-70 years) were studied during hospitalization. All patients were found to have an increased heart rate x systolic blood pressure product before the onset of angina decubitus, indicating that this type of angina pectoris belongs to the category of effort angina. Of the 11 patients investigated by continuous hemodynamic monitoring, 3 had significant progressive increases in pulmonary artery systolic pressure (PASP) and pulmonary artery diastolic pressure (PADP) before onset: their episodes of angina could not be completely controlled by digoxin and diuretics, but quickly subsided after beta blockers were added. Among the other 8 patients, PADP increased slightly in 5 and remained unchanged in 3 cases before onset: these patients had no manifestations of LV dysfunction, and beta blockers combined with coronary vasodilators produced satisfactory effects. These results indicate that LV failure is not a major factor in the pathogenesis of angina decubitus. The LV diastolic dysfunction seen in 8/11 cases may have been related to LV hypertrophy caused by long-term hypertension or chronic persistent ischemia.

Adrenergic beta-Antagonists↗

PubMed1992

Clinical evaluation of 99mTc-MIBI myocardial tomography for detecting coronary artery disease.

To evaluate the clinical efficacy of 99mTc-MIBI myocardial tomography for detecting coronary artery disease, 34 consecutive patients who underwent both 99mTc-MIBI study and coronary arteriography were included in the present study. Ten without and 24 with significant coronary artery disease were documented by coronary arteriography. The overall sensitivity and specificity of 99mTc-MIBI study for detecting coronary artery disease were 91.8% (22/24) and 80.0% (8/10), respectively. In subset studies, 16 of 17 (94.1%) patients with previous myocardial infarction and 6 of 7 (85.7%) patients with significant CAD but without MI were identified as abnormal. Reversible perfusion abnormalities were shown in 4 of 5 patients undergoing both exercise and rest studies. Rest perfusion abnormalities were shown in 2 patients with unstable angina pectoris who underwent only rest study. In conclusion, 99mTc-MIBI myocardial tomography provides a reliable method for detecting coronary artery disease. Rest study has high sensitivity for identifying patients with MI, and exercise/rest study can identify patients with significant CAD but without MI.

Coronary Disease↗

PubMed1992

Quantitative assessment of regional wall motion abnormalities with 2DE in cases of myocardial infarction.

The severity, extent and localization of regional wall motion abnormalities (RWMA) were quantitatively assessed with apical biplane two-dimensional echocardiography (2DE) using a fixed-axis system, ten-segment division area method in 56 patients with old myocardial infarction (OMI). RWMA were found to be more severe in the anterior wall MI (AWMI) group than in the inferoposterior wall MI (IWMI) group and most severe in the extensive AWMI with ventricular aneurysm (EAWMI with VA) group; the extent of RWMA was smallest in the IWMI group, significantly larger in the AWMI group, and largest in the EAWMI with VA group. The location of the RWMA segments showed group-specific tendencies. For example, both coronal and sagittal apices were much more frequently involved in both the EAWMI with VA and the AWMI groups than in the IWMI group (100%, 87% and 0%, respectively, all P < 0.001). The results demonstrated that quantitative analysis of RWMA using 2DE in cases of MI is accurate and feasible.

Echocardiography↗

PubMed1992

[Reperfusion arrhythmias in acute myocardial infarction].

Twenty-seven patients with acute myocardial infarction (AMI), in whom infarct-related coronary artery was occluded and thrombolytic therapy or PTCA were performed, were studied. Reperfusion confirmed by immediate coronary angiography was achieved in 24 patients. Reperfusion arrhythmias (RA) occurred in 19(79.2%) of the patients, including ventricular arrhythmias in 13 (54.2%). Ventricular fibrillation (VF) and sustained ventricular tachycardia (VT) developed in 2(8.4%), and accelerated idioventricular rhythm in 5(20.8%); the latter showed a reliable indicator of coronary artery recanalization. Transient sinus bradycardia or AV block occurred in 10 (66.7%) of the 15 patients with inferior-posterior MI, which was an indicator of recanalization of coronary artery and salvage of myocardium in inferior-posterior MI. The occurrence of RA was not correlated with the duration of ischemia; ventricular RA was not related to the location of AMI and the occurrence and severity of ischemic arrhythmias before reperfusion. The patients with RA were treated with ordinary antiarrhythmic therapy, VF and sustained VT in 2 patients were converted by electric defibrillation. No death related to RA occurred. RA couldn't be prevented by lidocaine.

Aged↗

PubMed1991

Comparative epidemiology of cancers of the colon, rectum, prostate and breast in Shanghai, China versus the United States.

Incidence rates of cancers of the colon, rectum, female breast, and prostate were compared among native Chinese (Shanghai), Chinese-American, and American populations. Americans had fourfold higher age-adjusted rates of colon cancer, and twofold higher rates of rectal cancer than Chinese, which is consistent with elevated per capita intake of fat and lower intake of cereals and vegetables in the US. Incidence rates of colon and rectal cancers in Chinese-Americans were nearly equal to the American rates, suggesting that the risk for tumour development in the lower intestinal tract is rapidly increased with transition to the US diet. Rates of prostate cancer and postmenopausal breast cancer were 26-fold and tenfold higher in Americans than in Chinese, whereas the rates for Chinese-Americans were intermediate. Environmental factors such as dietary fat apparently had a more gradual effect in promoting cancers of the breast and prostate relative to their influence on neoplasms of the lower intestinal tract.

Breast Neoplasms↗

PubMed1991

Intravenous recombinant tissue-type plasminogen activator in acute myocardial infarction.

The efficacy and safety of intravenously administered recombinant tissue-type plasminogen activator (rt-PA, Boehringer Ingelheim Corp.) was investigated in 10 patients with acute myocardial infarction (AMI). rt-PA was given as a 10 mg bolus dose followed by infusions of 50 mg, 20 mg and 20 mg in three successive hours. All patients underwent baseline coronary angiography before thrombolytic therapy. Ninety minutes after the initiation of rt-PA infusion, recanalization of infarct-related coronary arteries as confirmed by angiography was achieved in 7 patients. The largest reduction in circulating fibrinogen was observed 4 to 6 h after the start of rt-PA infusion--14.3%. Moderate hemorrhage at the sites of arterial puncture occurred in 2 cases, probably as a result of heparin anticoagulation. No other side effects occurred. So rt-PA is an effective and safe thrombolytic agent.

Aged↗

PubMed1991

Secondary prevention of myocardial reinfarction with low dose aspirin.

A clinical trial of secondary prevention of reinfarction with low dose aspirin is reported. 50 mg aspirin per day was administered in 216 case. 211 cases did not take aspirin or any other antiplatelet agents as a control group. The follow-up periods in the two groups were 19.4 +/- 12.6 mon and 20.7 +/- 13.0 mon, respectively. There were 175 males in the aspirin group and 137 males in the control group. The incidence of reinfarction was reduced by 65% and platelet aggregation was inhibited obviously in the aspirin group as compared to the control group in men, whereas no significant trends were observed in women.

Aged↗

PubMed1991

[Intravenous recombinant tissue-type plasminogen activator in acute myocardial infarction].

The efficacy and safety of intravenous administration of recombinant tissue-type plasminogen activator (rt-PA, made by Boehringer Ingelheim Corp.) was investigated in 10 patients with acute myocardial infarction (AMI). The rt-PA was given as a bolus dose of 10 mg followed by an infusion of 50 mg, 20 mg and 20 mg in successive hours. Heparin and aspirin were given to all the patients. The time interval from the onset of chest pain to thrombolysis was from 2.3 to 6.1 h with mean of 3.9 h. Coronary angiography, performed before administration of rt-PA and every 30 minutes thereafter, demonstrated total coronary occlusion (grade O) in 9 patients and grade 1 in 1 at baseline study. The infarct-related coronary artery were LAD in 5, RCA in 3 and LCX in 2. At 90 minutes after infusion of rt-PA reperfusion of the infarct-related artery was observed in 7 patients, the success rate was 70%. In one case the infarct-related LCX was not opened at 90 minutes, but it was reperfused at 170 minutes, after intracoronary administration of 10 mg of rt-PA. The total dose in this case was 130 mg. During 30 days of hospitalization death occurred in only one case with cardiogenic shock, in whom the infarct-related RCA was not reperfused by rt-PA but was successfully recanalized by PTCA. The patient died from rupture of the left ventricle on the 4th day. No patient had clinical evidence of reinfarction. Follow-up angiography in 2 patients showed that the arteries reperfused initially were patent.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

PubMed1991

[Vitrectomy for nondiabetic vitreous hemorrhage].

Fifty cases (fifty-three eyes) of nondiabetic vitreous hemorrhage underwent vitrectomy. The visual acuity improved in 39 eyes (73.6%) postoperatively. Twenty seven eyes obtained a visual acuity of 0.05 or better. The postoperative vision was related to the etiology and macular function. Vitreous hemorrhage due to blunt trauma responded best. All of them had vision improved. Eales's disease also had a good result. 77% was improved in vision postoperatively. The main complications of surgery were recurrent vitreous hemorrhage and secondary glaucoma, especially hemolytic glaucoma (4/6). The timing for vitrectomy, degree of cutting and hemolytic glaucoma were briefly discussed.

Adolescent↗