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Biomedical subjects

R Gao

Publications and source records attributed to R Gao.

119 records · Page 7Linked to original sources
PubMed1991

[Bullous retinal detachment and its classification of fluorescence angiography].

Nineteen cases with (27 eyes) of bullous retinal detachment, male (24 eyes), female (3 eyes), were reported. The age of onset was from 16 to 46, mean 36.7. All of them underwent fundus fluorescence angiography (FFA). According to the results of FFA, it could be divided into two types of fluorescence angiograph changes were seen: type I, multiple pigmental epithelial damage at posterior pole, it consisted of twelve cases (16 eyes); type II, extensive pigmental epithelial damage at posterior pole, it consisted of seven cases (11 eyes). The treatments consist: medicine; medicine and photocoagulation; combined medicine, transscleral drainage and photocoagulation. Among 27 eyes, 20 had their vision improved after treatment, 4 eyes unchanged and 3 eyes decreased in vision. 22 eyes obtained their retinal reattachment (81.4%). The diagnosis, differential diagnosis, classification and treatment are discussed.

Adolescent↗
PubMed1991

[Comparison of Chinese traditional therapy combined with Western medicine and Western medicine alone in the treatment of uveitis].

Seventy nine eyes of 46 patients with uveitis were treated with two therapeutic methods. One was mainly Chinese traditional dialectic therapy combined with western medicine. The other was western medica treatment using mainly corticosteroid. The group treated with combined methods (37 eyes of 22 cases) showed an effective rate of 91.8%. The group treated only with western medicine (42 eyes of 24 cases) showed a 66.6% < effective rate. In a follow-up period of six months to one year. The disease relapsed in 13 eyes out of the 33 eyes in the combined method group with recurrent rate of 39.4%. The recurrent rate of the western medical treatment was 86.4% (19 eyes out of the 22 eyes). It shows the Chinese traditional dialectic therapy combined with eastern medicine is better than the solely western medical treatment.

Adolescent↗
PubMed1991

[Evaluation of clinical criteria of coronary artery recanalization in acute myocardial infarction].

Clinical features of recanalization of infarct-related coronary artery during thrombolytic therapy or emergency PTCA and their correlation with immediate coronary angiography were analysed in 23 patients with acute myocardial infarction (AMI) to evaluate the predictive value of clinical criteria of reperfusion. The coronary angiography was performed before treatment and every 15 to 30 minutes during intravenous (rt-PA) or intracoronary (UK or SK) thrombolysis. Reperfusion was achieved in 16 cases by thrombolysis and in 4 cases by PTCA. The results revealed that in patients with reperfusion chest pain was relieved rapidly at least 70% in a period of 30 minutes, the ST segments fell by 50% or more from their elevated levels during a period of 30 minutes. Transient "paradoxical" increase of ST segment elevation followed by rapid falling was observed in 4 patients. This phenomenon was considered as a reliable marker of reperfusion. The changes in cardiac rhythm and conduction were noticed in 90% of the patients with reperfusion, among them accelerated idioventricular rhythm and disappearance of new-onset AVB and intraventricular conduction defects were useful bedside evidences of reperfusion, and transient significant sinus bradycardia or AVB with or without transient hypotension were useful markers of reperfusion in inferior myocardial infarction. When these clinical criteria were separately used as predictor of infarct-related coronary artery recanalization, the specificity was about 70% to 80%. Using the presence of all 3 criteria, the specificity and predictive value increased to 100% and the sensitivity was 70.6%. The time interval between onset of symptoms and peak CK and CK-MB were significantly shorter in patients with reperfusion than in those without persistent reperfusion.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1990

Studies on medicamentous inhibitory therapy for esophageal precancerous lesions--3- and 5-year inhibitory effects of antitumor-B, retinamide and riboflavin.

Since 1983, we have been conducting inhibitory therapy for precancerous lesions of the esophagus in two regions of Henan Province considered high-risk areas of esophageal carcinoma. Our goal was to effect a 50% reduction in the canceration rate of marked esophageal dysplasia. By means of a cytological survey, 2531 cases of marked esophageal dysplasia and 3393 cases of mild esophageal dysplasia were selected. The former were randomly divided into 3 groups for antitumor-B (ATB, a mixture of Chinese herbs), retinamide (4-ethoxycarbophenylretinamide) and placebo treatment respectively, and the latter into 2 groups treated with riboflavin and placebo respectively. Treatment was continued for 3 or 5 years (administration rate greater than 90% in all groups) and esophageal cytology reexamined (reexamination rates were 94.1% and 92.5% respectively). Our results were as follows: 1) ATB 3- and 5-year subjects saw the canceration rate of marked esophageal dysplasia drop by 52.2% and 47.3% respectively as compared to control (P less than 0.01). 2) Retinamide lowered the canceration rate by 37.3% after a 3-year treatment period, with this reduction reaching 43.2% after an additional 2 years of treatment with increased dosages (P less than 0.05, P less than 0.01). 3) In the riboflavin group, the canceration rate of mild esophageal dysplasia was reduced by 22.2% and 34.8% after 3 and 5 years of treatment respectively, but these differences were not statistically significant. The above results verify the efficacy of medicamentous inhibitory therapy for esophageal precancerous lesions.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

Micro-vitreous surgery combined with scleral encircling for the management of complex retinal detachment.

50 cases (50 eyes) of various complex retinal detachments (RD) were treated with a combination of vitrectomy, membrane peeling, intraocular air tamponade and scleral encircling. RD with opaque media, RD with proliferative vitroretinopathy, traction RD due to trauma or other factors, RD with posterior breaks, and giant tears were included. During the follow-up periods of 3-12 months, 27 cases (54%) obtained anatomic reattachment, 23 failed (46%). Of the successful case, 24 eyes achieved improvement, 2 eyes remained unchanged, and one eye became worse in their vision. The surgery complications were: retinal haemorrhage, choroidal haemorrhage, iatrogenic tears, and the development of cataract.

Adolescent↗
PubMed1990

[Iatrogenic central artery embolism].

This paper presented 3 cases of central retinal artery embolism (CRAE) caused by the drug injection at the head and neck. In two of the three cases, the emboli were formed by the suspended drug which entered CRA resulting in the occlusion. Another case was caused by the large amount of meglucamini diatrizoas which was injected too quickly during angiography. The CRA was filled up with fluorescein in a very short time, which lead to ischemia and hypoxia of the retina. This paper stressed the importance of early diagnosis and prompt treatment. The authors also Discussed the method of drug injection at the head and neck.

Adolescent↗
PubMed1990

[Obliterative peripheral retinal vascular disease in children].

Obliterative peripheral retinal vascular disease in children is a rare disease. Only 4 cases had been reported abroad. No case of this disease was reported in China before. This paper reported a 13-year-old girl suffering from this disease in both eyes. Neovascular glaucoma of her left eye has developed and that of her right eye was still in early stage. Fluorescein angiography changes, diagnosis and differential diagnosis, pathogenesis and treatment of the disease were discussed.

Adolescent↗
PubMed1990

[New approach for management of retinal detachment with macular hole].

Three kinds of unconventional methods were used to treat retinal detachment with macular hole in 17 cases (17 eyes). A combination of vitrectomy, transscleral drainage and intraocular air injection was used for the cases of retinal detachment with macular hole and evident vitreous traction. Transscleral drainage combined with air injection was used for those of macular hole without vitreous traction. For the cases of combined peripheral and macular holes, we treated only peripheral holes, ignoring the macular hole. After a 3-16 months follow-up, 15 out of the 17 eyes obtained retinal anatomic reattachment (88.2%), 10 eyes had their vision improved, 4 eyes remained unchanged, 9 eyes obtained a visual acuity of better than 0.05 postoperatively. Compared with the conventional method of macular buckling, these procedures have the advantages of less damage to macula, less complications and more satisfactory visual improvement.

Adult↗
PubMed1990

[A study on treatment of retinal detachment with unseen retinal breaks].

64 cases (66 eyes) of retinal detachment in which no breaks can be found were treated with pars plana vitrectomy, scleral buckling or encircling procedures. The selection of operation depended on the shape and size of retinal detachment, the position of peripheral retinal lattice degeneration, phakia or aphakia, traumatic situation and the appearance of proliferative vitreoretinopathy. The results showed that the detached retina was successfully reattached in 53 eyes (80.3%), 4 eyes were improved (6%), only 9 eyes failed (16.7%). The technic of operation and application are discussed. We consider that suitable active surgical treatment for this kind of cases is encouraging.

Adolescent↗
PubMedDate not supplied

Evaluation of the clinical value of combination of 99mTc-MIBI myocardial SPECT and 18F-FDG PET in assessing myocardial viability.

PURPOSE: To evaluate the value of 18F-FDG PET metabolic imaging and 99mTc-MIBI SPECT in the identification of myocardial viability in patients with previous myocardial infarction and left ventricular dysfunction. METHODS: 18F-FDG PET (made in China) and 99mTc-MIBI SPECT were performed in 60 patients (pts) (age 54+/-9 yr) with myocardial infarction before revascularization. Before and after revascularization, LVEF and wall motion were measured with echocardiography in 36 pts (Group A), and myocardial perfusion was evaluated in 24 pts (Group B). RESULTS: According to the interpretation of perfusion and metabolic images, myocardial segments were classified into mismatch (MM): reduced myocardial perfusion and normal FDG uptake or match (M): reduced perfusion and FDG uptake. Out of 264 segments with hypoperfusion, 145 (54.9%) were MM, suggesting viable myocardium (G-A1 and G-B1), 119 (45.1%) were M, suggesting necrosis (G-A2 and G-B2). After revascularization, LVEF was increased in G-A1 (49+/-15% vs. 59+/-7%, p<0.05), and in G-B1 (50+/-8% vs. 59+/-12%, p<0.05), but was not improved in G-A2 and G-B2. LVEDD was decreased in G-A1 and G-B1 (p<0.05) and was unchanged in G-A2 and G-B2. The positive predictive value (PPV) of FDG PET for improvement of regional wall motion after revascularization was 88%, and the negative predictive value (NPV) was 72.6%. The PPV for improvement of perfusion was 84.1%, NPV was 85%, and accuracy was 84.4%. CONCLUSION: 18F-FDG imaging with Chinese PET has clinical value for assessing myocardial viability and identifying patients who will benefit from revascularization.

Evaluation Studies as Topic↗