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Biomedical subjects

R Hensley

Publications and source records attributed to R Hensley.

8 recordsLinked to original sources
PubMed1995

In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus.

Human immunodeficiency virus type 1 (HIV-1)-infected patients (n = 335) in the US Air Force HIV Natural History Program were followed for 3 years (mean) after skin testing, immunophenotyping of CD4+ cell subsets, and measurement of in vitro interleukin-2 production after stimulation by phytohemagglutinin, alloantigens, tetanus toxoid, and influenza A virus. The T cell functional assay predicted survival time (P < .001) and time for progression to AIDS (P = .014). Skin testing for tetanus, mumps, and Candida antigen and the total number of positive tests (P < .001 for each) stratified patients for survival time. In a multivariable proportional hazards model, the T cell functional assay (P = .008), the absolute number of CD4+ T cells (P = .001), the percentage of CD4+ CD29+ cells (P = .06), and the number of reactive skin tests (P < .001) predicted survival time. Thus, cellular immune functional tests have significant predictive value for survival time in HIV-1-infected patients independent of CD4+ cell count.

Acquired Immunodeficiency Syndrome↗
PubMed1993

Developing community-based program alternatives for the seriously and persistently mentally ill elderly.

The deinstitutionalization movement in the United States has traditionally neglected the rehabilitation potential of the seriously mentally ill elderly. With the proliferation of the elderly population, unique programs and community-based settings must be created and expanded to meet the mental health needs of this population in a cost-effective and humane manner. The mental health continuum presented is a model composed of programs that target the seriously mentally ill elderly in a variety of community placements including residential treatment facilities, nursing homes, retirement homes, and permanent housing.

Aged↗
PubMed1989

An examination of the relationship between childhood depression and social competence amongst primary school children.

Forty-three primary school children who scored in the clinical range of the Children's Depression Inventory were compared with 43 children who were categorized as fearful but not depressed and a control group of 43 children who were classed as nondepressed-nonfearful. Subjects were matched across groups on the basis of grade and sex. The analyses were performed twice, initially with a depressed sample that excluded any depressed-fearful children and again with a depressed group that included such children. The results revealed that, independent of whether the depressed category included children who were also fearful, the depressed group reported lower levels of assertiveness and greater submissiveness, less adequate social skills performance, received lower ratings of peer popularity, fewer positive nominations from peer sociometry and more negative nominations. Depressed children were much more likely to be rejected or isolated by their peers than were their fearful or control counterparts.

Child↗
PubMed1989

Distorting patient or distorting instrument? Body shape disturbance in patients with anorexia nervosa and bulimia.

Three current techniques for estimating body size (Image Marking, Visual Size Estimation, and Distorting Video techniques) were compared. Anorexia nervosa and bulimic patients and normal control subjects were required to make size judgments of the way they 'knew' they looked, the way they 'felt' they looked, and of the width of an inanimate control object. Results from the three techniques were not the same, thus implying that research findings can no longer be cross-compared. Moreover, while all subjects were similar in the accuracy of their estimation of a control object, anorexia nervosa and bulimic patients overestimated their own body size significantly more than normal controls. This difference was even more marked when affective instructions were compared.

Adolescent↗
PubMed1978

Paired associate learning in early infantile autism and receptive developmental aphasia.

A comparative study of nonverbal MA matched groups of five autistic, five aphasic, five normal and five retarded children was made on an auditory-visual and a visual-visual paired-associate learning task. The results showed that, although the autistic and receptive aphasic children were both unable to associate sounds with their visual counterparts at the same rate as normal children, the aphasic children overcame this deficit at a significantly faster rate than autistic children. This study pinpoints one dysfunction that could subsume the severe verbal comprehension defect in autistic and aphasic children.

Adolescent↗