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Biomedical subjects

R I Ceilley

Publications and source records attributed to R I Ceilley.

At least 37 records · Page 2Linked to original sources
PubMed1981

Auricular malignant neoplasms. When is chemotherapy (Mohs' technique) necessary?

A prospective study of 71 auricular malignant neoplasms was performed to identify lesions with a high risk of recurrence. Previously recommended margins for conventional surgical excision were marked. Then, all lesions were excised by the Mohs' technique. The Mohs' defect was compared with previously marked margins for conventional excision. Conventional excision would have been inadequate in 13% of primary and initially recurrent lesions smaller than 1 cm (clinical examination) and in 27% of primary lesions and 33% of recurrent lesions larger than 1 cm. All cases successfully excised by conventional excision would have resulted in a larger defect than the actual Mohs' defect. Morpheaform basal cell carcinoma was the most common lesion inadequately excised. Either cases of this histologic type or lesions larger than 1 cm or both require consideration for the use of the Mohs' technique.

Adult↗
PubMed1981

Complications of fiber implantation for baldness.

Several methods of fiber implantation have been used to reduce pattern baldness, and similar results have been reported: fiber breakage, foreign-body reaction, infection and scarring. Since one method or another tends to predominate in different geographic areas, the physician often is unable to compare the results of the various methods. The two patients described in this article underwent different methods of fiber implantation; serious complications occurred in both. Fiber implantation is an unsafe technique and must be discouraged.

Adult↗
PubMed1980

Cell-mediated immunity in patients with basal and squamous cell skin cancer.

T and B lymphocyte levels were normal in fifty patients with basal and squamous cell skin cancer. Patients with basal cell carcinomas and small squamous cell carcinomas reacted normally to intradermal antigens and to dinitrochlorobenzene (DNCB). However, patients with large (greater than 3 cm) squamous cell carcinomas appeared to have defective systemic cell-mediated immunity because only 33% of them reacted to at least one intradermal antigen, and only 67% could be sensitized to DNCB. Presently, it is unknown whether this defect is related to the occurrence or behavior of squamous cell carcinoma.

Adult↗
PubMed1980

Stellate excision of malignancies on the auricles.

Primary excision of malignancies on the auricles with the standard "wedge technique" may produce lateral protrusion of the helix. A stellate-type excision eliminates the possibility of this undesirable effect and allows the surgeon to close large defects in the helix. The technique is described in detail.

Ear Neoplasms↗
PubMed1980

Secondary intention healing as an adjunct to the reconstruction of mid-facial defects.

Facial skin cancer has a high incidence during later life. The majority of our patients had been previously treated by a number of different modalities. The recurrence of persistance of their cutaneous neoplasm was often quite extensive and thus required a rather large excision to eradicate the disease. Employment of a number of small operations under local anesthesia in which the patients could return to their home environment provided for a potential reduction in psychological and physical morbidity. The use of delayed healing often allowed reconstruction with a local flap or skin graft that if reconstructed primarily would have necessitated a more extensive operative procedure. Use of local flaps and/or skin grafts avoided excessive blood loss and long periods of immobilization associated with larger regional and distant flaps. Finally the denial of reconstructive surgery because of age should be condemned since fairly small operations in conjunction with delayed wound healing can provide acceptable cosmetic and functional results.

Aged↗
PubMed1980

Amelanotic melanoma presenting as a pyogenic granuloma.

A sixty-two year old man was diagnosed as having an amelanotic of the right great toe after the lesion had been treated for several months as a pyogenic granuloma. Establishment of the correct diagnosis was aided by the finding of a radiolucent defect on a roentgenogram of the toe. Since amelanotic melanoma usually presents as a vascular or ulcerated nodule, rather than as a pigmented nevus, the lesion may be mistaken for a benign tumor. This case illustrates the necessity of histologic confirmation of all presumed pyogenic granulomas. Furthermore, it also stresses that clinical, histologic, and prognostic distinctions must be made between amelanotic melanoma and its pigmented counterpart.

Diagnosis, Differential↗
PubMed1979

Nasal skin cancer:hazard to a uniquely exposed structure.

The nose is one of the most common sites of malignancy on the face, probably because of its unique position of exposure to environmental damage. By far the most common type of nasal tumor is basal cell carcinoma. Squamous cell carcinoma is less common but considerably more aggressive, with a tendency to fast growth and metastasis. Tumors of either type are more likely to invade easily and resist treatment if they are in certain "danger zones." Nasal skin cancer in general has a relatively good prognosis, regardless of the type of treatment selected, ie, surgery, radiotherapy, cryotherapy, or electrodesiccation and curretage. However, tumors that are not eradicated have a long history of recurrences before proving fatal. When ablative surgery is performed, some type of reconstructive procedure is usually necessary.

Basal Cell Carcinoma↗
PubMed1979

Aggressive biologic behavior of basal- and squamous-cell cancers in patients with chronic lymphocytic leukemia or chronic lymphocytic lymphoma.

Three basal- and four squamous-cell carcinomas in seven patients with chronic lymphocytic leukemia or chronic lymphocytic lymphoma recurred repeatedly after conventional treatment, and grew to large sizes. The squamous-cell carcinomas metastasized in all four of the patients so afflicted. Absolute numbers of circulating T lymphocytes were normal in the seven patients, but they had cutaneous anergy to intradermal tests with common antigens and to dinitrochlorobenzene. The following recommendations for management of cutaneous carcinomas in patients with malignant lymphomatoses are made: 1) closer surveillance than for patients with cutaneous cancers but without malignant lymphomatoses, 2) early treatment of actinic keratoses to prevent possible transformation to malignancy, and 3) microscopically controlled excision of basal- or squamous-cell carcinomas larger than 1 cm in diameter.

Aged↗