PubMed Health⌕ Search

Biomedical subjects

R Kaneko

Publications and source records attributed to R Kaneko.

At least 73 records · Page 4Linked to original sources
PubMed1986

Giant cell fibroma of the oral mucosa. Report of a case with ultrastructural study.

A case of giant cell fibroma of the oral mucosa found in a 3-year-old female is reported. The lesion was characterized histologically by the presence of numerous large stellate cells and multinucleated giant cells scattered in a loosely arranged collagen-background. The large stellate cells had a large hyperchromatic nucleus, while the cytoplasm was well demarcated and frequently the cells had dendritic-like processes. The multinucleated giant cells had similar morphology and occasionally resembled Langhans' giant cells. Ultrastructural examination suggested that the multinucleated giant cells in the lesion were unusual fibroblasts. This is the first reported case of oral giant cell fibroma in a Japanese patient.

Child, Preschool↗
PubMed1984

Ameloblastic fibrosarcoma in the maxilla, malignant transformation of ameloblastic fibroma.

This report presents a fatal case of ameloblastic fibrosarcoma arising from an ameloblastic fibroma, originating in the maxilla of 19-year-old Japanese male. An analysis of previously reported fatal cases of ameloblastic fibrosarcoma is included. In the course of the disease, the mesenchymal component of ameloblastic fibroma showed a dramatic histopathological transformation into sarcoma following multiple recurrence and the patient died of uncontrollable local infiltration of the cranial base. Although many cases have seemed to show disappearance of the epithelial component as malignant transformation progressed, many benign appearing ameloblastoid epithelial masses were scattered throughout the sarcomatous area even in the fatal stage in the present case. No distant metastases were found at autopsy. During multiple recurrences of the lesion, a little dysplastic dentin which was closely associated with both epithelial and mesenchymal components was found, though it could not be observed in autopsy material. Ultrastructural findings in autopsy material showed that the mesenchymal component consisted of undifferentiated mesenchymal cells, fibroblastic and fibrocytic cells with marked cellular and nuclear pleomorphism and that the epithelial component closely resembled the enamel organ.

Adult↗
PubMed1984

Effect of caerulein administration on portal plasma somatostatin in dogs.

The effect of administration of synthetic caerulein on canine plasma somatostatin concentration in the portal vein was investigated using specific radioimmunoassay of acid-acetone extracted plasma. Gel chromatography revealed that the main component of the plasma somatostatin in the portal vein was identical with somatostatin-14. After administration of caerulein (5 ng/kg), the somatostatin level increased significantly while the gastrin level remained unchanged. These results suggested that caerulein affects D cell function but not gastrin secretion.

Animals↗