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Biomedical subjects

R Krivosic-Horber

Publications and source records attributed to R Krivosic-Horber.

At least 109 records · Page 6Linked to original sources
PubMed1985

[Computerized records for obstetrical epidural analgesia].

An original recording and exploiting data programme has been built. It is in Basic language for Apple II. The data programme allows the care of obstetric peridural analgesic records. The medical interest is the record edition which is possible when the patient comes back. The scientific interest is statistics produced quickly from a great number of records. The record, record edition and statistical edition are described.

Anesthesia, Epidural↗
PubMed1984

[Technics for artificial ventilation of a single lung during thoracotomy].

Different means of limiting the fall in arterial PO2 produced by single artificial ventilation were studied in 60 patients during thoracotomy. Changing from ventilating both lungs to the one healthy lung in the lateral recumbent position, without modifying tidal volume and frequency, brought about a fall in arterial PO2 from 180 +/- 56 to 67 +/- 40 mmHg. The alveolar to arterial oxygen gradient increased to 110 +/- 45 mmHg (the alveolar oxygen pressure being calculated). Reducing the tidal volume so as to keep the inflation pressure at its initial level did not improve the arterial PO2 but slightly increased the arterial PCO2 (2.3 mmHg). The use of 6 to 8 cm H2O positive end-expiratory pressure did not significantly modify the arterial PO2 or PCO2. Increasing the inspired oxygen fraction from 0.5 to 0.7 increased the arterial PO2 from 100 +/- 89 mmHg to 165 +/- 59 mmHg, whilst the alveolar to arterial oxygen gradient increased to 118 +/- 60 mmHg. Clamping the pulmonary artery increased the arterial PO2 and dual lung ventilation restored it to its initial value. Therefore, the only effective means of increasing oxygenation was to increase the inspired oxygen fraction. Unilateral continuous positive airway pressure was not used so as not to impair surgery. Dual lung ventilation may be necessary if the arterial PO2 remains low.

Blood Gas Analysis↗
PubMed1983

[Sodium nitroprusside and coronary surgery].

The anti-hypertensive properties of sodium nitroprusside have been tested in 20 patients undergoing coronary arterial surgery. Were measured the arterial pressure, heart rate, mean right atrial pressure and mean left atrial pressure. The cardiac output, systemic vascular resistance and left ventricular stroke work index were deduced. A dose of 0.8 to 3 micrograms . kg-1 . min-1 sodium nitroprusside was given at the start of surgery, and immediately afterwards. The results showed a decrease of the systemic vascular resistance, a significant drop of arterial pressure, and a significant increase of heart rate as well as a tendency for the cardiac output to fall, probably because of insufficient vascular filing. When the mean left atrial pressure was kept at 14.8 +/- 3 mmHg (1.97 +/- 0.40 kPa), and left ventricular stroke work index fell, whilst cardiac output increased. Sodium nitroprusside seemed to be useful in coronary arterial surgery if used with care.

Adult↗
PubMed1981

[Circulating anticoagulant and open heart surgery (author's transl)].

Two patients presenting an unsettled mitral cardiopathy had to receive a valve replacement under cardiopulmonary by-pass in spite of a circulating anticoagulant with antiprothrombinase activity. A higher risk of thromboembolic trouble required an increase of heparin administration, under a strict biological control. Nevertheless both patients died: the first of coronary thrombosis, the second of cataclysmic bleeding, associated to severe and diffused thrombosis. Thus it is essential to insist upon the risk occurred by those patients and the difficulty of adaptation and control of heparin administration.

Blood Coagulation Disorders↗
PubMed1980

[Severe head-injury of the child. Medical treatment (author's transl)].

The child with a severe head injury requires a three component's treatment: against cerebral edema, against restlessness and vegetative trouble, against shock in case of scalp-hemorrage or attendant traumatism. As there is no agreement neither about the treatment of cerebral edema nor that of sedative treatment, we continue to use systematically artificial ventilation, sometimes corticoids, rarely mannitol. Decerebration is treated by a lytic coktail enclosing always diazepam and in case of failure, sodium gamma-hydroxybutyrate.

Adolescent↗
PubMed1980

[Anesthetic management for delivery of 38 cardiac patients (author's transl)].

The choice of anesthesia is discussed in connection with a serie of 38 women cardiac and pregnant cared from 1976 to 1979, 32 of them having delivered a child. Peridural analgesia improves the labour and the delivery without inconveniene for either mother of child, but general anesthesia must be prefered for cesarean section. Anticoagulant therapy is a contra-indication for peridural analgesia.

Analgesia↗