The VER: a status report. An experimental but not clinically significant tool.
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Afferent Pathways↗
Biomedical subjects
R M Burde
Publications and source records attributed to R M Burde.
Central origin of oculomotor parasympathetic neurons in the monkey.
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Animals↗
Bilateral optic nerve sheath meningiomas.
A 35-year-old man was initially seen following the incidental discovery of swollen optic disc in both eyes. Over a subsequent 15-year period, the patient experienced an inexorable loss of vision in both eyes, characterized by normal neuroradiologic findings and the presence of opticocillary shunt vessels on both discs. A craniotomy ultimately demonstrated the presence of bilateral optic nerve sheath meningiomas that appeared to have arisen multifocally.
Adult↗
Binocular diplopia associated with subretinal neovascular membranes.
A series of patients were seen with binocular diplopia secondary to subretinal neovascular membrane in one eye. The pathophysiology underlying the diplopia is the establishment of rivalry between central and peripheral fusional mechanisms. This diplopia is not relieved by appropriate prism therapy.
Adult↗
Bilateral optic atrophy caused by chronic oral ingestion and topical application of hexachlorophene.
A 31-year-old woman ingested hexachlorophene (pHisoHex) over a ten-month period. She developed bilateral optic atrophy with no other systemic evidence of neurotoxicity. This cases supports pathologists' findings that the optic nerve and chiasm are particularly sensitive to the poisonous effects of hexachlorophene.
Administration, Oral↗
Disappearing opticociliary shunt vessels and pseudotumor cerebri.
In two patients opticociliary venous shunts occurred in association with pseudotumor cerebri. One patient underwent bilateral optic nerve sheath fenestrations, after which her papilledema resolved, and the opticociliary venous shunts were noted to be markedly decreased in caliber.
Adult↗
Accommodation defect in Wilson's disease.
A 22-year-old man with Wilson's disease had blurred vision caused by a defect of accommodation that we believed to be supranuclear in origin.
Accommodation, Ocular↗
Optic disk edema in sarcoidosis.
A 24-year-old woman had bilateral optic disk edema. A granulomatous uveitis and macular edema subsequently ensued. Histologic examination of a biopsy specimen taken from an area of marked hilar adenopathy revealed noncaseating epithelioid cell tubercles. No other associated systemic findings were noted, and after a course of topical and systemic corticosteroid therapy, the ocular manifestations disappeared.
Adult↗
Headache and the ophthalmologist.
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Anxiety↗
Cell-mediated immunity and sex.
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Animals↗
Cataracts induced by topical dexamethasone in diabetics.
Eleven diabetic patients were treated with unilateral topical dexamethasone for 14 to 36 months in an attempt to control their retinopathy. Cataracts developed in the treated eye of nine patients, compared with only one cataract in an untreated eye.
Administration, Topical↗
Cytomegalovirus in juvenile iridocyclitis.
We cultured cytomegalovirus from lens material aspirated from the eye of a 4-year-old boy who had a severe bilateral iridocyclitis and secondary cataracts. There were neither systemic manifestations of congenital disease nor chorioretinitis.
Child, Preschool↗
Clinician's guide to the pupil.
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Eye Movements↗
Experimental internuclear ophthalmoplegia.
A midline experimental lesion separating the medial longitudinal fasciculi at and below the level of the abducens nuclei without damaging either fasciculus at the level of the nuclei has produced defects of ocular motility resembling those of clinical internuclear ophthalmoplegia. Electromyographic recordings during lateral gaze demonstrate: (1) lack of inhibition of the lateral rectus muscle in the adducting eye, (2) delayed inhibition of the medial rectus muscle in the abducting eye, and (3) occasional evidence of excitation of the medial rectus muscle of the abducting eye probably associated with pupillary constriction. The presumed physiologic mechanisms involved in conjugate gaze movements are discussed in the light of the experimental findings.
Animals↗
Management of dysthyroid optic neuropathy.
The diagnosis of dysthyoid ophthalmopathy is based on clinical observation of characteristic ophthalmic abnormalities. Proper diagnosis and initiation of treatment should not be delayed because a patient is found to be euthyroid. Although visual problems in dysthyroid ophthalmopathy are uncommon this disorder can result in permanent severe visual loss if optic neuropathy is not detected early and managed properly. Oral corticosteroid therapy and surgical decompression both seem to have a place in the treatment of dysthyroid ophthalmopathy with optic neuropathy.
Adrenal Cortex Hormones↗
Visual recovery after central retinal artery occlusion: two cases.
Two cases of central retinal artery occlusion of prolonged duration (greater than 6 hours) were treated with retrobulbar anesthesia, anterior chamber paracentesis, and high-dose carbon dioxide and oxygen inhalation. Both cases recovered excellent vision and illustrate that visual recovery after relatively prolonged central retinal artery occlusion is possible.
Anesthesia, Local↗