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Biomedical subjects

R O Greer

Publications and source records attributed to R O Greer.

At least 37 records · Page 2Linked to original sources
PubMed1985

Primary malignant melanoma of the oral cavity. A review of 177 cases.

Malignant melanoma of the oral cavity is rare, accounting for about 1% to 8% of all melanomas. There have been no prospective studies of melanoma in this location, and all previous papers have reported small numbers of cases or have retrospectively reviewed case reports from the literature. The authors report six new cases and review 171 cases published since the last major review in 1975. The classification of oral melanomas with radial growth phases is discussed.

Adult↗
PubMed1983

Oral tissue alterations associated with the use of smokeless tobacco by teen-agers. Part I. Clinical findings.

The use of smokeless tobacco appears to be finding its way onto middle school, high school and college campuses as a socially acceptable and popular habit. Numerous reports in the literature have described the oral changes that appear to be associated with the use of smokeless tobacco in adults. Such information is unavailable for the lower age groups. A study was therefore undertaken to determine the prevalence and frequency of oral hard- and soft-tissue alterations associated with the use of smokeless tobacco in a teen-age population. High school students in grades 9 to 12 were evaluated on a random basis. From a total sample of 1,119 students, 117 users of smokeless tobacco were identified. Four distinct lesions associated with smokeless tobacco use were identified clinically: (1) hyperkeratotic or erythroplakic lesions of the oral mucosa, (2) gingival or periodontal inflammation, (3) a combination of oral mucosal lesions and periodontal inflammation, and (4) cervical erosion of the teeth. Among the smokeless tobacco users, 113 were boys and 4 were girls. Fifty-seven (48.7 percent) of the users had soft-tissue lesions and/or periodontal inflammation or erosion of dental hard tissues. Ninety-nine of the 117 users were Caucasian, 6 were Hispanic, 1 was black, 1 was Asian, 1 was an American Indian, and 6 failed to identify an ethnic origin. Use ranged from one to twenty "dips" per day, with an average time per dip of 30 minutes. Most users had been dipping for an average of 2 years, and twelve different tobacco brands were identified.

Adolescent↗
PubMed1983

Adenomatoid odontogenic tumor: clinicopathologic and ultrastructural concepts.

Two cases of adenomatoid odontogenic tumor have been presented, along with a review of the literature. One tumor had a rather typical presentation, occurring in a 12-year-old in association with an impacted canine tooth. Subsequent electron microscopic evaluation of this case provided corroboration of other recently published findings. In this case there was a striking accumulation of what could have been secretory granules at the pole of the cell nearest a "duct-like" space. This cell had ultrastructural characteristics in common with a preameloblast. The second case occurred in a more unusual situation, the patient being a 32-year-old man, with the AOT developing in the mandible between the roots of the canine and first premolar. Both patients were treated successfully by simple enucleation of the lesion.

Adult↗
PubMed1982

The incidence of Sjögren's sicca complex in a population of patients with keratoconjunctivitis sicca.

A prospective study was performed on patients who came to a university ophthalmology outpatient clinic with the complaint of dry eyes and who were documented to have keratoconjunctivitis sicca (KCS). Of 45 patients studied 1 had primary amyloidosis, and another 10 had KCS with a previously diagnosed connective tissue disease. Of the remaining 34 patients, 19 had KCS alone without xerostomia, and the remaining 15 had KCS in association with subjective or objective xerostomia. Eight of these 15 patients were subsequently shown to have clinical Sjögren's syndrome--sicca complex, and for the majority, serologic and biopsy findings supported this diagnosis.

Adult↗
PubMed1979

Focal odontodysgenesis of the maxillary second premolars in a child.

A few months before her sixth birthday, a Caucasian girl suffered progressively worse episodes of painful, nontender, erythematous swellings of the palate lingual to apparently healthy primary second molars. Neither of the developing maxillary second premolars was discerned clearly in radiographs, but, upon surgical exploration, incomplete crowns were found in both follicles. All the other premolars appeared to be developing normally. Histologic, histochemical, and chemical analyses showed that the enamel was hypocalcified, apparently as a result of hypomaturation; the dentin was essentially normal; and morphogenesis had ceased when the heights of contour of the crowns had not yet been reached. This pattern of developmental defects differs from those of well-characterized odontogenic disorders, such as regional odontodysplasia and amelogenesis imperfecta. We suggest that focal odontodysgenesis might be an appropriate term for it. The bilateral symmetry suggests a genetic component in the etiology.

Bicuspid↗
PubMed1978

Osteoblastoma of the jaws: current concepts and differential diagnosis.

A review of previously documented cases of osteoblastoma has been presented and an additional case has been reported. Although the clinical and histologic distinctions for fibrous-osseous lesions cover a wide spectrum, several means of differentiating osteoblastoma from similar lesions have been discussed. A larger series of cases will allow us to further delineate clinical, histologic, and biologic variables of osteoblastoma.

Adolescent↗
PubMed1977

Differential diagnosis of some simple osseous lesions associated with sickle-cell anemia.

Sickle-cell disease is characterized by chronic hemolytic anemia, rapid destruction of defective erythrocytes, with consequent circulatory disturbances. Thromboses and infarctions with resultant osseous manifestations tend to be localized in the ends of the long bones or in the medullary area, the latter often becoming apparent in the jaws. Three case reports are presented to illustrate osseous changes observed in the jaws of these sickle-cell patients. The radiographic findings demonstrate the adaptive mechanisms of bone metabolism in response to vascular infarction, infection, or both in some sickle-cell anemia patients. A differential diagnosis is suggested for osseous lesions observed in the jaws of these patients.

Adolescent↗
PubMed1977

Primary intraoral sarcoidosis.

A case of sarcoidosis manifesting primarily in the oral cavity has been documented and clinicopathological findings are discussed. The diagnosis of sarcoidosis can nearly always be established by an assessment of the clinical picture in combination with the histologic features of an adequate biopsy specimen. The Kveim test is a useful tool in clinical diagnosis, but is not always positive in patients with sarcoidosis. The clinician should also be aware that false positives can occur. Scalene node biopsy can also be a useful diagnostic adjunct. The current case emphasizes that biopsy of an intraoral lesion, scalene node biopsy, and Kveim testing are useful in establishing a diagnosis of sarcoidosis.

Diagnosis, Differential↗