Biomedical subjects

R Pautrizel

Publications and source records attributed to R Pautrizel.

57 records · Page 4Linked to original sources

PubMedDate not supplied

[Affinity of concanavalin A for "trypanosoma equiperdum": purification of the antigenic type specific glycoprotein fraction (author's transl)].

Binding of concanavalin A by different clones of Trypanosoma equiperdum was checked by its ability to agglutinate living trypanosomes. The clones differ by their agglutinability, showing differences in the distribution of the binding sites. However, the property of concanavalin A to form precipitates with the crude antigen preparations of all the clones studied, allowed to isolate by affinity chromatography the glycoprotein fraction responsible for the antigenic variation and to enter upon its physicochemical study.

Agglutination↗

PubMedDate not supplied

[Seroepidemiological survey on toxoplasmosis in Guadeloupe and Martinique (author's transl)].

The examination of 9,950 serums in Guadeloupe and Martinique has revealed the importance and the precocity of infestation by Toxoplasma: 56,9% of the population has complement fixing antibodies, 65,6% haemagglutinating antibodies and from the very first age groups onwards, nearly half the population is found to be infested. Although the consumption of insufficiently cooked meat is most frequently invoked, it would seem that this manner of contamination should not be incriminated in Guadeloupe and Martinique where the population traditionally lives on fish and well-cooked meat. Moreover, the great variability in the rates of infestation observed in the different localities studied leads one to envisage the invtervention of climatic factors favoring the survival of the oocysts born of the sexed multipilication of the parasite in the external environment.

Adolescent↗

PubMedDate not supplied

[Experimental trypanosomiasis in rabbits infected by Trypanosoma equiperdum: some aspects of immune response and coagulation disorders (author's transl)].

Some aspects of immune response and coagulation disorders are investigated on rabbits infected by two strains of Trypanosoma (Trypanozoon) equiperdum giving diseases with different clinical expression. The study of antibodies to trypanosomes emphasizes the high immunogenicity of specific antigenic type glycoprotein, antigenicity of which seems to inhibit common antigens expression. Significant increase of anti-fibrinogen antibodies is discussed in relation with the presence of autoantibodies frequently discovered along trypanosomiasis. As IgM they contribute to the classical hypermacroglobulinemia of these diseases. Their casual contribution in the contribution in the casual contribution in the observed disorders is argued. The meaning of fibrinolytic system activation which is shown by FDP significant increase is equally argued: secondary fibrinolysis or Hageman Factor activation mediated by immune complexes.

Animals↗