PubMed Health⌕ Search

Biomedical subjects

R Pyle

Publications and source records attributed to R Pyle.

22 records · Page 2Linked to original sources

The value of urography after angiocardiography. A survey of 300 cases.

Routine films were taken of the kidneys after contrast studies of the heart and great vessels in 300 consecutive patients using the Sircam) 100-mm camera. A significant amount of information was obtained at low cost and with minimal radiation of the patient. A standard was established for normal sizes of kidneys using this format. There were 56 abnormalities, including 26 pairs of kidneys that differed significantly in size (19% and 9%). There were 2 tumors, 2 cysts, 19 congenital abnormalities, 1 renal artery stenosis, 4 renal and 1 biliary stone. One of the tumors, undetected at a previous angiographic examination, was inoperable, and earlier detection would have undoubtedly benefited and may have offered a possible cure to this patient. The authors feel that the addition of this examination, trifling in the expenditure of time and money, is of definite benefit to the patient.

Adult↗

Followup study of possible HIV seropositivity among abusers of parenteral drugs in 1971-72.

Serum specimens obtained from a nationwide sample of parenteral drug abusers (PDAs) during the period 1971-72 had previously been screened for human immunodeficiency virus (HIV) antibodies. Some specimens were considered to be positive to both ELISA and Western blot (WB) analysis. These findings have been a topic of controversy, since HIV was not thought to have penetrated at-risk populations at such an early date. This study was a followup of those PDAs with apparent seropositivity to WB analysis. Of 10 persons followed, only one death (in 1985) was documented, and postmortem findings were inconsistent with HIV infection. Eight of the remaining PDAs were traced and found to be alive and well in 1989. Fresh specimens were obtained from the two persons with the strongest 1971-72 WB staining and were found to be both ELISA and WB negative on retesting. Their T-cell parameters were within normal limits. We concluded that the earlier WB results were most likely false positives and that definitive evidence of HIV infection in the U.S. addict population as early as 1971-72 is still lacking.

Blotting, Western↗