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Biomedical subjects

R Ruseva

Publications and source records attributed to R Ruseva.

At least 19 recordsLinked to original sources
PubMed2000

[Hyperplastic and metaplastic changes of the endometrium].

The hyperplastic and metaplastic changes of the endometrium most often coexist and are associated with hyperestrogenic status--exogenous hormones, hormoneproducing ovarian tumors, persisting anovylatory cycles, PCOS. The correct histologic diagnosis of metaplasia and the differential diagnosis with atypical hyperplasia and some types of endometrial carcinomas, especially in cases of pre-operative curettage specimen, are of greatest importance for the consecutive therapeutic approach.

Anovulation↗
PubMed1999

[The corticosteroid therapy of premature rupture of the fetal membranes].

Antenatal corticosteroids are now administered for the purpose of hastening maturation of the preterm infant's organs and tissues, thus reducing neonatal mortality and the incidence of respiratory distress syndrome (RDS). Our purpose was to determine the efficacy of maternal corticosteroid therapy on fetal maturation in cases with preterm premature rupture of the membranes. The rates of RDS and survival in low birth weight infants treated with corticosteroids is influenced by the duration of the premature rupture of the membranes and the duration of the corticosteroid therapy, as well as by the gestational age.

Adult↗
PubMed1999

[The dry period in preterm birth and premature rupture of the fetal membranes].

It is widely believed that premature rupture of membranes accelerates fetal pulmonary maturity. The purpose of our study was to determine the duration of the latent phase, in the cases of premature rupture of membranes, required to achieve this effect. Retrospective analysis of our database yielded a group of 42 patients, who were delivered between 26 and 34 weeks gestation. The results of this study suggest that pulmonary maturation continues but is not accelerated after premature rupture of membranes. Delaying delivery for more than 72 hours after rupture of membranes is more likely to result in chorioamnionitis than accelerated pulmonary maturation.

Adolescent↗
PubMed1999

[The preoperative preparation of the vagina with Betadine before abortion on demand].

Recent evidence has associated bacterial vaginosis and trichomoniasis with several postoperative complications. We carried out a prospective study aiming to estimate the frequency of vaginitis in women wanting to make an artificial abortion and the possibility to influence this infections by local application of vaginal BETADINE suppositories in all forms of infectious vaginitis: Candida albicans, trichomonas vaginalis and bacterial vaginosis.

Abortion, Legal↗
PubMed1999

[Second trimester pregnancy termination with and without prostaglandins].

The effectiveness of three methods for second trimester pregnancy termination [TOP) was compared. A retrospective analysis was made in 34 cases with TOP by intraamniotic saline instillation and 19 cases with extra-amniotic appreciation of y ballon-catheter, followed by stimulation of uterine contractions by intravenous oxytocin infusion. The results were compared with the ones in 13 prospectively studied cases in which the extra-amniotic appreciation of the ballon-catheter was preceded by treatment of the cervix with 0.5 mg prostin E2 intracervically. In nulliparous patients the treatment of the cervix with y single dose prostaglandins did not shorten the mean abortion time neither reduced the percentage of unsuccessful and prolonged abortions. In parous patients the abortion time was significantly reduced. No failed or prolonged abortions were registered.

Abortifacient Agents↗
PubMed1997

[Fetal diaphragmatic hernia. Concomitant anomalies].

According to different investigations congenital diaphragmatic hernia (CDH) is associated with other anomalies in 29% to 53%. The aim of our study was to present our experience with the prenatal diagnosis of CDH and to analyse the associated anomalies. For a ten-year period there were 18 fetuses born after 24 gestational week with CDH. The associated anomalies were found in 66.7%, most common they involved the nervous system, the heart and the kidneys. Our results confirm that there is a concentration of the most severe and with the worst prognosis cases of CDH in the bid neonatal centers.

Abnormalities, Multiple↗
PubMed1997

[The prognostic indices in congenital diaphragmatic hernia. Its management].

The reported mortality for prenatally detected congenital diaphragmatic hernia is high. We retrospectively reviewed 18 cases of congenital diaphragmatic hernia diagnosed prenatally in our hospital and analyzed several high-risk factors adversely affecting outcome. The diagnosis before 32 weeks gestation is associated with high mortality than in cases detected later. Polyhydramnios and underdevelopment of left-side cardiac structures were found to be helpful prognostic factors. These should be taken into account when the management of these cases is planed.

Bulgaria↗
PubMed1997

[The effect of the duration of the dry period and of the use of antibiotics on the development of congenital infection in the newborn infant during premature rupture of the fetal membranes].

A retrospective study including 41 patients with preterm premature rupture of the membranes (PPROM) was carried out to investigate the influence of some factors (interval between PPROM and delivery, antibiotic administration) on the development of congenital infections of the newborn. When the PPROM--delivery interval exceeds 168 hours the infection rate is very high. The latter is lower when cephalosporin antibiotics instead of ampicillin are administered to the pregnant patient with PPROM.

Anti-Bacterial Agents↗
PubMed1996

[Fetal diaphragmatic hernia. Its incidence and outcome after a 5-year period].

The reported mortality of the newborns with congenital diaphragmatic hernia is high. We retrospectively reviewed 10 cases of congenital diaphragmatic hernia (CDH), which were born in the University Maternal Hospital in Sofia for a five year period. Three of the fetuses died before birth, five died in the first 30 minutes after birth and two underwent operation for the correction of the diaphragmatic defect. Pulmonary hypoplasia is without doubt associated with CHD and is responsible for the high mortality. There is no doubt a degree of pulmonary hypoplasia precludes survival, but it is difficult to define this degree.

Bulgaria↗
PubMed1995

[Defects of the anterior abdominal wall--their prenatal management].

The rate of the congenital malformations: gastroschisis and omphalocele, the prenatal management and the clinical issue were analyzed in a retrospective study during a period from January 1990 till October 1994 in the State Maternity Hospital "Maĭchin dom". The aim of the study was to establish the accuracy of the prenatal sonographic diagnosis of the defects of abdominal wall, the gestational age they were found out, and the perinatal issue of the affected newborn infants. The rate of the abdominal walls defects was 1:1525. They were diagnosed prenatally in 52% of the cases. The fatality rate among the alive-born infants with these malformations was 77%. The frequency of the associated anomalies with defects of the abdominal wall was 71%, which exceeds the mean frequency in Europe and presents one of the most important factors determining the high fatality rate.

Abdominal Muscles↗
PubMed1995

[The location of the placenta in pregnant women with one or more past cesarean sections].

We examined 282 pregnant women who have had one or more previous cesarean sections. The localization of placenta was done with ultrasound after 32 weeks of gestation. The control group consists of 1560 pregnant women without previous operative births. Placenta praevia is found in 3.9% in patients with previous cesarean sections and in 0.45% in the control group. The bleeding in the group of placenta praevia after previous operative births is observed in 44.4% against 28.5% when the placenta praevia is in intact uterus. A significant dependence was found between the number of sections and the risk of placenta praevia and bleedings in the following pregnancy. Placenta praevia shows preference to the anterior uterine wall in 67% in scared uterus and in 33% in intact uterus. A very poor is the combination of febrile postoperative period with endometritis and very short interval to the next pregnancy. These conclusions are important for the prognosis and management of such pregnancies.

Adult↗