[Therapeutic effects of hydroquinidine in atrial fibrillation].
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Biomedical subjects
Publications and source records attributed to R Sandri.
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In most regimens proposed for the depletive management of cirrhosis of the liver, spirolactone is associated with other diuretics. Treatment of 28 patients with uncompensated forms by means of spirolactone only, using high, protracted doses determined essentially in accordance with the depletion obtained, is described. The disappearance of signs of water retention was gradual and unattended by difficulties. Normalisation of the urinary Na/K ratio preceded the diuretic response; Increased diuresis led to a slight increase in urinary potassium/day. Higher doses were used in patients with lower urinary Na/K ratios. Here a critical diuretic response was only obtained around the 5th day. Transient low blood sodium and chlorine and high blood potassium were noted; the last parameter was not related to the drug dose, nor to changes in Bun; No marked changes in blood uric acid, calcium, ammonium, bilirubin or sugar were observed.
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Notes on the anatomical and physiological features of the circulation are followed by a description of the main physiopathological aspects of the terminal circulation of the lower extremities. Reference is made to the pathogenesis and clinical and instrumental diagnosis of plantar ulcers in alcoholic polyneuritis, along with the symtoms constantly observed in a series of some 30 cases.
A case of fatal, diffused plasmacytoma is presented. The picture also included leukaemia and is felt to be an example of plasma-cell leukaemia, as opposed to plasmacytoma in the light of the anatomical and clinical features of the onset and course: high and very pronounced plasma-cell leukocytosis, diffuse proliferation of the plasma cell series in the bone marrow, spleen and lymph nodes, infiltration of plasma cells in the parenchymal organs, extremely rapid progress with serious anaemia, haemorrhage, general organic involvement, high fever, and infection.
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